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IFNA4 (interferon alpha 4)

Identity

Alias_symbol (synonym)MGC142200
IFN-alpha4a
Other aliasINFA4
HGNC (Hugo) IFNA4
LocusID (NCBI) 3441
Atlas_Id 56418
Location 9p21.3  [Link to chromosome band 9p21]
Location_base_pair Starts at 21186619 and ends at 21187599 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFNA4   5425
Cards
Entrez_Gene (NCBI)IFNA4  3441  interferon alpha 4
AliasesIFN-alpha4a; INFA4
GeneCards (Weizmann)IFNA4
Ensembl hg19 (Hinxton)ENSG00000236637 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000236637 [Gene_View]  chr9:21186619-21187599 [Contig_View]  IFNA4 [Vega]
ICGC DataPortalENSG00000236637
TCGA cBioPortalIFNA4
AceView (NCBI)IFNA4
Genatlas (Paris)IFNA4
WikiGenes3441
SOURCE (Princeton)IFNA4
Genetics Home Reference (NIH)IFNA4
Genomic and cartography
GoldenPath hg38 (UCSC)IFNA4  -     chr9:21186619-21187599 -  9p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFNA4  -     9p21.3   [Description]    (hg19-Feb_2009)
EnsemblIFNA4 - 9p21.3 [CytoView hg19]  IFNA4 - 9p21.3 [CytoView hg38]
Mapping of homologs : NCBIIFNA4 [Mapview hg19]  IFNA4 [Mapview hg38]
OMIM147564   
Gene and transcription
Genbank (Entrez)BC074965 BC074966 BC113640 BC113642 HQ258102
RefSeq transcript (Entrez)NM_021068
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFNA4
Cluster EST : UnigeneHs.1510 [ NCBI ]
CGAP (NCI)Hs.1510
Alternative Splicing GalleryENSG00000236637
Gene ExpressionIFNA4 [ NCBI-GEO ]   IFNA4 [ EBI - ARRAY_EXPRESS ]   IFNA4 [ SEEK ]   IFNA4 [ MEM ]
Gene Expression Viewer (FireBrowse)IFNA4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3441
GTEX Portal (Tissue expression)IFNA4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05014   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05014  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05014
Splice isoforms : SwissVarP05014
PhosPhoSitePlusP05014
Domaine pattern : Prosite (Expaxy)INTERFERON_A_B_D (PS00252)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Interferon_alpha/beta/delta   
Domain families : Pfam (Sanger)Interferon (PF00143)   
Domain families : Pfam (NCBI)pfam00143   
Domain families : Smart (EMBL)IFabd (SM00076)  
Conserved Domain (NCBI)IFNA4
DMDM Disease mutations3441
Blocks (Seattle)IFNA4
SuperfamilyP05014
Human Protein AtlasENSG00000236637
Peptide AtlasP05014
HPRD00952
IPIIPI00291465   
Protein Interaction databases
DIP (DOE-UCLA)P05014
IntAct (EBI)P05014
FunCoupENSG00000236637
BioGRIDIFNA4
STRING (EMBL)IFNA4
ZODIACIFNA4
Ontologies - Pathways
QuickGOP05014
Ontology : AmiGOadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  cytokine activity  type I interferon receptor binding  protein binding  extracellular region  extracellular space  humoral immune response  blood coagulation  response to virus  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  innate immune response  defense response to virus  type I interferon signaling pathway  regulation of type I interferon-mediated signaling pathway  
Ontology : EGO-EBIadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  cytokine activity  type I interferon receptor binding  protein binding  extracellular region  extracellular space  humoral immune response  blood coagulation  response to virus  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  innate immune response  defense response to virus  type I interferon signaling pathway  regulation of type I interferon-mediated signaling pathway  
Pathways : KEGG   
NDEx NetworkIFNA4
Atlas of Cancer Signalling NetworkIFNA4
Wikipedia pathwaysIFNA4
Orthology - Evolution
OrthoDB3441
GeneTree (enSembl)ENSG00000236637
Phylogenetic Trees/Animal Genes : TreeFamIFNA4
HOVERGENP05014
HOGENOMP05014
Homologs : HomoloGeneIFNA4
Homology/Alignments : Family Browser (UCSC)IFNA4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFNA4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFNA4
dbVarIFNA4
ClinVarIFNA4
1000_GenomesIFNA4 
Exome Variant ServerIFNA4
ExAC (Exome Aggregation Consortium)IFNA4 (select the gene name)
Genetic variants : HAPMAP3441
Genomic Variants (DGV)IFNA4 [DGVbeta]
DECIPHERIFNA4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFNA4 
Mutations
ICGC Data PortalIFNA4 
TCGA Data PortalIFNA4 
Broad Tumor PortalIFNA4
OASIS PortalIFNA4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFNA4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFNA4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFNA4
DgiDB (Drug Gene Interaction Database)IFNA4
DoCM (Curated mutations)IFNA4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFNA4 (select a term)
intoGenIFNA4
Cancer3DIFNA4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147564   
Orphanet
MedgenIFNA4
Genetic Testing Registry IFNA4
NextProtP05014 [Medical]
TSGene3441
GENETestsIFNA4
Target ValidationIFNA4
Huge Navigator IFNA4 [HugePedia]
snp3D : Map Gene to Disease3441
BioCentury BCIQIFNA4
ClinGenIFNA4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3441
Chemical/Pharm GKB GenePA29664
Clinical trialIFNA4
Miscellaneous
canSAR (ICR)IFNA4 (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFNA4
EVEXIFNA4
GoPubMedIFNA4
iHOPIFNA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:12:47 CEST 2017

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