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IFNA5 (interferon alpha 5)

Identity

Alias_namesinterferon
Alias_symbol (synonym)IFN-alphaG
Other aliasIFN-alpha-5
INA5
INFA5
leIF G
HGNC (Hugo) IFNA5
LocusID (NCBI) 3442
Atlas_Id 56374
Location 9p21.3  [Link to chromosome band 9p21]
Location_base_pair Starts at 21304614 and ends at 21305313 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFNA5   5426
Cards
Entrez_Gene (NCBI)IFNA5  3442  interferon alpha 5
AliasesIFN-alpha-5; IFN-alphaG; INA5; INFA5; 
leIF
GeneCards (Weizmann)IFNA5
Ensembl hg19 (Hinxton)ENSG00000147873 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147873 [Gene_View]  chr9:21304614-21305313 [Contig_View]  IFNA5 [Vega]
ICGC DataPortalENSG00000147873
TCGA cBioPortalIFNA5
AceView (NCBI)IFNA5
Genatlas (Paris)IFNA5
WikiGenes3442
SOURCE (Princeton)IFNA5
Genetics Home Reference (NIH)IFNA5
Genomic and cartography
GoldenPath hg38 (UCSC)IFNA5  -     chr9:21304614-21305313 -  9p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFNA5  -     9p21.3   [Description]    (hg19-Feb_2009)
EnsemblIFNA5 - 9p21.3 [CytoView hg19]  IFNA5 - 9p21.3 [CytoView hg38]
Mapping of homologs : NCBIIFNA5 [Mapview hg19]  IFNA5 [Mapview hg38]
OMIM147565   
Gene and transcription
Genbank (Entrez)BC093755 BC093757 V00541
RefSeq transcript (Entrez)NM_002169
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFNA5
Cluster EST : UnigeneHs.37113 [ NCBI ]
CGAP (NCI)Hs.37113
Alternative Splicing GalleryENSG00000147873
Gene ExpressionIFNA5 [ NCBI-GEO ]   IFNA5 [ EBI - ARRAY_EXPRESS ]   IFNA5 [ SEEK ]   IFNA5 [ MEM ]
Gene Expression Viewer (FireBrowse)IFNA5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3442
GTEX Portal (Tissue expression)IFNA5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01569   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01569  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01569
Splice isoforms : SwissVarP01569
PhosPhoSitePlusP01569
Domaine pattern : Prosite (Expaxy)INTERFERON_A_B_D (PS00252)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Interferon_alpha/beta/delta   
Domain families : Pfam (Sanger)Interferon (PF00143)   
Domain families : Pfam (NCBI)pfam00143   
Domain families : Smart (EMBL)IFabd (SM00076)  
Conserved Domain (NCBI)IFNA5
DMDM Disease mutations3442
Blocks (Seattle)IFNA5
SuperfamilyP01569
Human Protein AtlasENSG00000147873
Peptide AtlasP01569
HPRD00953
IPIIPI00003077   
Protein Interaction databases
DIP (DOE-UCLA)P01569
IntAct (EBI)P01569
FunCoupENSG00000147873
BioGRIDIFNA5
STRING (EMBL)IFNA5
ZODIACIFNA5
Ontologies - Pathways
QuickGOP01569
Ontology : AmiGOadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  c9toiine activity  cytokine receptor binding  type I interferon receptor binding  extracellular region  extracellular space  humoral immune response  blood coagulation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  innate immune response  defense response to virus  type I interferon signaling pathway  regulation of type I interferon-mediated signaling pathway  
Ontology : EGO-EBIadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  cytokine activity  cytokine receptor binding  type I interferon receptor binding  extracellular region  extracellular space  humoral immune response  blood coagulation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  innate immune response  defense response to virus  type I interferon signaling pathway  regulation of type I interferon-mediated signaling pathway  
Pathways : KEGG   
NDEx NetworkIFNA5
Atlas of Cancer Signalling NetworkIFNA5
Wikipedia pathwaysIFNA5
Orthology - Evolution
OrthoDB3442
GeneTree (enSembl)ENSG00000147873
Phylogenetic Trees/Animal Genes : TreeFamIFNA5
HOVERGENP01569
HOGENOMP01569
Homologs : HomoloGeneIFNA5
Homology/Alignments : Family Browser (UCSC)IFNA5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFNA5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFNA5
dbVarIFNA5
ClinVarIFNA5
1000_GenomesIFNA5 
Exome Variant ServerIFNA5
ExAC (Exome Aggregation Consortium)IFNA5 (select the gene name)
Genetic variants : HAPMAP3442
Genomic Variants (DGV)IFNA5 [DGVbeta]
DECIPHERIFNA5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFNA5 
Mutations
ICGC Data PortalIFNA5 
TCGA Data PortalIFNA5 
Broad Tumor PortalIFNA5
OASIS PortalIFNA5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFNA5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFNA5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFNA5
DgiDB (Drug Gene Interaction Database)IFNA5
DoCM (Curated mutations)IFNA5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFNA5 (select a term)
intoGenIFNA5
Cancer3DIFNA5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147565   
Orphanet
MedgenIFNA5
Genetic Testing Registry IFNA5
NextProtP01569 [Medical]
TSGene3442
GENETestsIFNA5
Target ValidationIFNA5
Huge Navigator IFNA5 [HugePedia]
snp3D : Map Gene to Disease3442
BioCentury BCIQIFNA5
ClinGenIFNA5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3442
Chemical/Pharm GKB GenePA29665
Clinical trialIFNA5
Miscellaneous
canSAR (ICR)IFNA5 (select the gene name)
Probes
Litterature
PubMed68 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFNA5
EVEXIFNA5
GoPubMedIFNA5
iHOPIFNA5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:12:47 CEST 2017

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