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IFNA8 (interferon alpha 8)

Identity

Alias_namesinterferon
Alias_symbol (synonym)IFN-alphaB
Other alias
HGNC (Hugo) IFNA8
LocusID (NCBI) 3445
Atlas_Id 56254
Location 9p21.3  [Link to chromosome band 9p21]
Location_base_pair Starts at 21409147 and ends at 21410185 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFNA8   5429
Cards
Entrez_Gene (NCBI)IFNA8  3445  interferon alpha 8
AliasesIFN-alphaB
GeneCards (Weizmann)IFNA8
Ensembl hg19 (Hinxton)ENSG00000120242 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120242 [Gene_View]  chr9:21409147-21410185 [Contig_View]  IFNA8 [Vega]
ICGC DataPortalENSG00000120242
TCGA cBioPortalIFNA8
AceView (NCBI)IFNA8
Genatlas (Paris)IFNA8
WikiGenes3445
SOURCE (Princeton)IFNA8
Genetics Home Reference (NIH)IFNA8
Genomic and cartography
GoldenPath hg38 (UCSC)IFNA8  -     chr9:21409147-21410185 +  9p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFNA8  -     9p21.3   [Description]    (hg19-Feb_2009)
EnsemblIFNA8 - 9p21.3 [CytoView hg19]  IFNA8 - 9p21.3 [CytoView hg38]
Mapping of homologs : NCBIIFNA8 [Mapview hg19]  IFNA8 [Mapview hg38]
OMIM147568   
Gene and transcription
Genbank (Entrez)BC104828 BC104830 K01900 V00545 V00550
RefSeq transcript (Entrez)NM_002170
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFNA8
Cluster EST : UnigeneHs.73890 [ NCBI ]
CGAP (NCI)Hs.73890
Alternative Splicing GalleryENSG00000120242
Gene ExpressionIFNA8 [ NCBI-GEO ]   IFNA8 [ EBI - ARRAY_EXPRESS ]   IFNA8 [ SEEK ]   IFNA8 [ MEM ]
Gene Expression Viewer (FireBrowse)IFNA8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3445
GTEX Portal (Tissue expression)IFNA8
Human Protein AtlasENSG00000120242-IFNA8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP32881   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP32881  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP32881
Splice isoforms : SwissVarP32881
PhosPhoSitePlusP32881
Domaine pattern : Prosite (Expaxy)INTERFERON_A_B_D (PS00252)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Interferon_alpha/beta/delta   
Domain families : Pfam (Sanger)Interferon (PF00143)   
Domain families : Pfam (NCBI)pfam00143   
Domain families : Smart (EMBL)IFabd (SM00076)  
Conserved Domain (NCBI)IFNA8
DMDM Disease mutations3445
Blocks (Seattle)IFNA8
SuperfamilyP32881
Human Protein Atlas [tissue]ENSG00000120242-IFNA8 [tissue]
Peptide AtlasP32881
HPRD00955
IPIIPI00031075   
Protein Interaction databases
DIP (DOE-UCLA)P32881
IntAct (EBI)P32881
FunCoupENSG00000120242
BioGRIDIFNA8
STRING (EMBL)IFNA8
ZODIACIFNA8
Ontologies - Pathways
QuickGOP32881
Ontology : AmiGOadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  cytokine activity  cytokine receptor binding  type I interferon receptor binding  extracellular region  extracellular space  humoral immune response  blood coagulation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  innate immune response  defense response to virus  type I interferon signaling pathway  regulation of type I interferon-mediated signaling pathway  
Ontology : EGO-EBIadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  cytokine activity  cytokine receptor binding  type I interferon receptor binding  extracellular region  extracellular space  humoral immune response  blood coagulation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  innate immune response  defense response to virus  type I interferon signaling pathway  regulation of type I interferon-mediated signaling pathway  
Pathways : KEGG   
NDEx NetworkIFNA8
Atlas of Cancer Signalling NetworkIFNA8
Wikipedia pathwaysIFNA8
Orthology - Evolution
OrthoDB3445
GeneTree (enSembl)ENSG00000120242
Phylogenetic Trees/Animal Genes : TreeFamIFNA8
HOVERGENP32881
HOGENOMP32881
Homologs : HomoloGeneIFNA8
Homology/Alignments : Family Browser (UCSC)IFNA8
Gene fusions - Rearrangements
Tumor Fusion PortalIFNA8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFNA8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFNA8
dbVarIFNA8
ClinVarIFNA8
1000_GenomesIFNA8 
Exome Variant ServerIFNA8
ExAC (Exome Aggregation Consortium)ENSG00000120242
GNOMAD BrowserENSG00000120242
Genetic variants : HAPMAP3445
Genomic Variants (DGV)IFNA8 [DGVbeta]
DECIPHERIFNA8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFNA8 
Mutations
ICGC Data PortalIFNA8 
TCGA Data PortalIFNA8 
Broad Tumor PortalIFNA8
OASIS PortalIFNA8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFNA8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFNA8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFNA8
DgiDB (Drug Gene Interaction Database)IFNA8
DoCM (Curated mutations)IFNA8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFNA8 (select a term)
intoGenIFNA8
Cancer3DIFNA8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147568   
Orphanet
DisGeNETIFNA8
MedgenIFNA8
Genetic Testing Registry IFNA8
NextProtP32881 [Medical]
TSGene3445
GENETestsIFNA8
Target ValidationIFNA8
Huge Navigator IFNA8 [HugePedia]
snp3D : Map Gene to Disease3445
BioCentury BCIQIFNA8
ClinGenIFNA8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3445
Chemical/Pharm GKB GenePA29668
Clinical trialIFNA8
Miscellaneous
canSAR (ICR)IFNA8 (select the gene name)
Probes
Litterature
PubMed72 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFNA8
EVEXIFNA8
GoPubMedIFNA8
iHOPIFNA8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:17:18 CET 2017

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