Identity
HGNC
LOCATION
21q22.11
LOCUSID
ALIAS
AVP,IFN-alpha-REC,IFNAR,IFNBR,IFRC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3454
MIM: 107450
HGNC: 5432
Ensembl: ENSG00000142166
Variants:
dbSNP: 3454
ClinVar: 3454
TCGA: ENSG00000142166
COSMIC: IFNAR1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37973454 | 2024 | Detection of interferon alpha and beta receptor subunit 1 (IFNAR1) loss-of-function Glu386∗ variant by tri-allelic genotyping. | 1 |
| 37973454 | 2024 | Detection of interferon alpha and beta receptor subunit 1 (IFNAR1) loss-of-function Glu386∗ variant by tri-allelic genotyping. | 1 |
| 37028439 | 2023 | Association of IFNAR1 and IFNAR2 with COVID-19 severity. | 3 |
| 37028439 | 2023 | Association of IFNAR1 and IFNAR2 with COVID-19 severity. | 3 |
| 34713375 | 2022 | A Case of Autosomal Recessive Interferon Alpha/Beta Receptor Alpha Chain (IFNAR1) Deficiency with Severe COVID-19. | 34 |
| 35048182 | 2022 | ZBTB28 inhibits breast cancer by activating IFNAR and dual blocking CD24 and CD47 to enhance macrophages phagocytosis. | 9 |
| 35288721 | 2022 | Ifnar gene variants influence gut microbial production of palmitoleic acid and host immune responses to tuberculosis. | 9 |
| 35339044 | 2022 | Expression analysis of IFNAR1 and TYK2 transcripts in COVID-19 patients. | 4 |
| 35442418 | 2022 | A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes. | 19 |
| 35708626 | 2022 | Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia. | 49 |
| 35816776 | 2022 | Beyond fusion: A novel role for ERVW-1 in trophoblast proliferation and type I interferon receptor expression. | 3 |
| 35985475 | 2022 | CK1α upregulates the IFNAR1 expression to prompt the anti-HBV effect of type I IFN in hepatoma carcinoma cells. | 1 |
| 36063748 | 2022 | Correlation between IFNAR1 expression in peripheral blood T lymphocytes and inflammatory cytokines, tumor-infiltrating lymphocytes, and chemosensitivity in patients with colorectal cancer. | 1 |
| 34713375 | 2022 | A Case of Autosomal Recessive Interferon Alpha/Beta Receptor Alpha Chain (IFNAR1) Deficiency with Severe COVID-19. | 34 |
| 35048182 | 2022 | ZBTB28 inhibits breast cancer by activating IFNAR and dual blocking CD24 and CD47 to enhance macrophages phagocytosis. | 9 |
Citation
Dessen P
IFNAR1 (interferon alpha and beta receptor subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40922/ifnar1
