IFNB1 (interferon, beta 1, fibroblast)

Identity

Other names	IFB
	IFF
	IFNB
	MGC96956
HGNC	IFNB1
Location	9p22
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	IFNB1   5434
Entrez_Gene	IFNB1  3456  interferon, beta 1, fibroblast
	Cards
GeneCards	IFNB1
Ensembl	IFNB1 [Search_View]   ENSG00000171855 [Gene_View]
Genatlas	IFNB1
GeneLynx	IFNB1
eGenome	IFNB1
euGene	3456
	Genomic and cartography
GoldenPath	IFNB1  -  9p22   chr9:21067104-21067943 -  9p21.3   [Description]    (hg18-March_2006)
Ensembl	IFNB1 - 9p21.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	IFNB1
	Gene and transcription
Genbank	BC069314 [ ENTREZ ]
Genbank	BC096150 [ ENTREZ ]
Genbank	BC096151 [ ENTREZ ]
Genbank	BC096152 [ ENTREZ ]
Genbank	BC096153 [ ENTREZ ]
RefSeq	NM_002176 [ SRS ]    NM_002176 [ ENTREZ ]
RefSeq	AC_000052 [ SRS ]    AC_000052 [ ENTREZ ]
RefSeq	AC_000141 [ SRS ]    AC_000141 [ ENTREZ ]
RefSeq	NC_000009 [ SRS ]    NC_000009 [ ENTREZ ]
RefSeq	NT_008413 [ SRS ]    NT_008413 [ ENTREZ ]
RefSeq	NW_001839149 [ SRS ]    NW_001839149 [ ENTREZ ]
RefSeq	NW_924062 [ SRS ]    NW_924062 [ ENTREZ ]
AceView	IFNB1 AceView - NCBI
Unigene	Hs.93177 [ SRS ]    Hs.93177 [ NCBI ]     HS93177 [ spliceNest ]
Fast-db	3331 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P01574 [ SRS]    P01574 [ EXPASY ]     P01574 [ INTERPRO ]     P01574 [ UNIPROT ]
Prosite	PS00252 INTERFERON_A_B_D [ SRS ]    PS00252 INTERFERON_A_B_D [ Expasy ]
Interpro	IPR012351 4_helix_cytokine_core [ SRS ]    IPR012351 4_helix_cytokine_core [ EBI ]
Interpro	IPR015588 IFNb [ SRS ]    IPR015588 IFNb [ EBI ]
Interpro	IPR000471 Interferon_abd [ SRS ]    IPR000471 Interferon_abd [ EBI ]
CluSTr	P01574
Pfam	PF00143 Interferon [ SRS ]    PF00143 Interferon [ Sanger ]    pfam00143 [ NCBI-CDD ]
Smart	SM00076 IFabd [EMBL]
Prodom	PD000550 Interferon_abd[INRA-Toulouse]
Prodom	P01574 IFNB_HUMAN [ Domain structure ]   P01574 IFNB_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P01574
PDB	1AU1 [ SRS ]    1AU1 [ PdbSum ],   1AU1 [ IMB ]   1AU1 [ RSDB ]
HPRD	00972
	Protein Interaction databases
DIP	P01574
IntAct	P01574
	Polymorphism : SNP, mutations, diseases
OMIM	147640    [ map ]
GENECLINICS	147640
SNP	IFNB1 [dbSNP-NCBI]
SNP	NM_002176 [SNP-NCI]
SNP	IFNB1 [GeneSNPs - Utah]  IFNB1] [HGBASE - SRS]
HAPMAP	IFNB1 [HAPMAP]
HGMD	IFNB1
	General knowledge
Family Browser	IFNB1 [UCSC Family Browser]
SOURCE	NM_002176
SMD	Hs.93177
SAGE	Hs.93177
GO	interferon-alpha/beta receptor binding [Amigo]  interferon-alpha/beta receptor binding
GO	extracellular region [Amigo]  extracellular region
GO	extracellular space [Amigo]  extracellular space
GO	induction of apoptosis [Amigo]  induction of apoptosis
GO	caspase activation [Amigo]  caspase activation
GO	caspase activation [Amigo]  caspase activation
GO	cell surface receptor linked signal transduction [Amigo]  cell surface receptor linked signal transduction
GO	negative regulation of cell proliferation [Amigo]  negative regulation of cell proliferation
GO	response to virus [Amigo]  response to virus
GO	natural killer cell activation [Amigo]  natural killer cell activation
GO	B cell proliferation [Amigo]  B cell proliferation
GO	defense response to bacterium [Amigo]  defense response to bacterium
GO	positive regulation of innate immune response [Amigo]  positive regulation of innate immune response
GO	regulation of MHC class I biosynthetic process [Amigo]  regulation of MHC class I biosynthetic process
GO	negative regulation of virion penetration into host cell [Amigo]  negative regulation of virion penetration into host cell
BIOCARTA	Cytokine Network    [Genes]
BIOCARTA	Dendritic cells in regulating TH1 and TH2 Development    [Genes]
BIOCARTA	IFN alpha signaling pathway    [Genes]
BIOCARTA	Signal transduction through IL1R    [Genes]
BIOCARTA	Cytokines and Inflammatory Response    [Genes]
BIOCARTA	Bone Remodelling    [Genes]
KEGG	Cytokine-cytokine receptor interaction
KEGG	Toll-like receptor signaling pathway
KEGG	Jak-STAT signaling pathway
KEGG	Natural killer cell mediated cytotoxicity
PubGene	IFNB1
TreeFam	IFNB1
CTD	3456 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	IFNB1 Related clones (RZPD - Berlin)
	PubMed
PubMed	103 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Sep 29 18:04:15 2008