Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3458
MIM: 147570
HGNC: 5438
Ensembl: ENSG00000111537
Variants:
dbSNP: 3458
ClinVar: 3458
TCGA: ENSG00000111537
COSMIC: IFNG
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000111537 | ENST00000229135 | P01579 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713366 | Tumor necrosis factor alpha (TNF-alpha) inhibitors | Chemical | ClinicalAnnotation | associated | PD | 24776844 | |
| PA443815 | Crohn Disease | Disease | ClinicalAnnotation | associated | PD | 24776844 | |
| PA446116 | Inflammatory Bowel Diseases | Disease | ClinicalAnnotation | associated | PD | 24776844 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37625543 | 2024 | ISG15-USP18 Dysregulation by Oxidative Stress Promotes IFN-γ Secretion from CD8+ T Cells in Vitiligo. | 2 |
| 37874649 | 2024 | Association between interferon-gamma (IFN-γ) gene polymorphisms and tuberculosis susceptibility: a systematic review and meta-analysis. | 0 |
| 38011610 | 2024 | Increased age-associated B cells in patients with acquired aplastic anemia correlate with IFN-γ. | 0 |
| 38101155 | 2024 | Evaluation of the presence of Th1 response through T-bet and IFN-gamma immunohistochemical expression in lower lip and oral tongue squamous cell carcinomas. | 0 |
| 38247871 | 2024 | Tryptophanyl-Transfer RNA Synthetase Is Involved in a Negative Feedback Loop Mitigating Interferon-γ-Induced Gene Expression. | 0 |
| 38286270 | 2024 | Cytokines signatures and susceptibility to cutaneous leishmaniasis in patients from Sistan and Baluchestan province of Iran. | 0 |
| 38300916 | 2024 | Human alveolar macrophages display marked hypo-responsiveness to IFN-γ in both proteomic and gene expression analysis. | 0 |
| 38368695 | 2024 | Effect of SARS-CoV-2 and Toxoplasma gondii co-infection on IFN-γ and TNF-α expression and its impact on disease severity. | 0 |
| 38381822 | 2024 | Spontaneous, persistent, T cell-dependent IFN-γ release in patients who progress to Long Covid. | 9 |
| 38406824 | 2024 | Implications of IFNγ SNP rs2069705 in primary Sjögren's syndrome: transcriptional activation and B cell infiltration. | 1 |
| 38424104 | 2024 | IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway. | 0 |
| 38488034 | 2024 | IFN‑γ induces apoptosis in gemcitabine‑resistant pancreatic cancer cells. | 1 |
| 38622605 | 2024 | Interferon-γ-induced GBP1 is an inhibitor of human papillomavirus 18. | 0 |
| 38627796 | 2024 | Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone mice. | 1 |
| 38675991 | 2024 | Association of the IFNG +874T/A Polymorphism with Symptomatic COVID-19 Susceptibility. | 0 |
Citation
Dessen P
IFNG (interferon gamma)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40925/ifng
