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IFNL2 (interferon lambda 2)

Identity

Alias_namesIL28A
interleukin 28A
interleukin 28A (interferon, lambda 2)
Alias_symbol (synonym)IL-28A
Other alias
HGNC (Hugo) IFNL2
LocusID (NCBI) 282616
Atlas_Id 45886
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 39268517 and ends at 39270092 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFNL2   18364
Cards
Entrez_Gene (NCBI)IFNL2  282616  interferon lambda 2
AliasesIL-28A; IL28A
GeneCards (Weizmann)IFNL2
Ensembl hg19 (Hinxton)ENSG00000183709 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183709 [Gene_View]  chr19:39268517-39270092 [Contig_View]  IFNL2 [Vega]
ICGC DataPortalENSG00000183709
TCGA cBioPortalIFNL2
AceView (NCBI)IFNL2
Genatlas (Paris)IFNL2
WikiGenes282616
SOURCE (Princeton)IFNL2
Genetics Home Reference (NIH)IFNL2
Genomic and cartography
GoldenPath hg38 (UCSC)IFNL2  -     chr19:39268517-39270092 +  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFNL2  -     19q13.2   [Description]    (hg19-Feb_2009)
EnsemblIFNL2 - 19q13.2 [CytoView hg19]  IFNL2 - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBIIFNL2 [Mapview hg19]  IFNL2 [Mapview hg38]
OMIM607401   
Gene and transcription
Genbank (Entrez)AY129148 AY184373 AY336715 BC113581 BC113583
RefSeq transcript (Entrez)NM_172138
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFNL2
Cluster EST : UnigeneHs.567792 [ NCBI ]
CGAP (NCI)Hs.567792
Alternative Splicing GalleryENSG00000183709
Gene ExpressionIFNL2 [ NCBI-GEO ]   IFNL2 [ EBI - ARRAY_EXPRESS ]   IFNL2 [ SEEK ]   IFNL2 [ MEM ]
Gene Expression Viewer (FireBrowse)IFNL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)282616
GTEX Portal (Tissue expression)IFNL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZJ0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZJ0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZJ0
Splice isoforms : SwissVarQ8IZJ0
PhosPhoSitePlusQ8IZJ0
Domains : Interpro (EBI)INF_lambda   
Domain families : Pfam (Sanger)IL28A (PF15177)   
Domain families : Pfam (NCBI)pfam15177   
Conserved Domain (NCBI)IFNL2
DMDM Disease mutations282616
Blocks (Seattle)IFNL2
SuperfamilyQ8IZJ0
Human Protein AtlasENSG00000183709
Peptide AtlasQ8IZJ0
HPRD09586
IPIIPI00218010   
Protein Interaction databases
DIP (DOE-UCLA)Q8IZJ0
IntAct (EBI)Q8IZJ0
FunCoupENSG00000183709
BioGRIDIFNL2
STRING (EMBL)IFNL2
ZODIACIFNL2
Ontologies - Pathways
QuickGOQ8IZJ0
Ontology : AmiGOmucosal immune response  receptor binding  cytokine activity  extracellular region  extracellular space  intracellular  JAK-STAT cascade  innate immune response  positive regulation of immune response  regulation of T cell activation  defense response to virus  defense response to virus  
Ontology : EGO-EBImucosal immune response  receptor binding  cytokine activity  extracellular region  extracellular space  intracellular  JAK-STAT cascade  innate immune response  positive regulation of immune response  regulation of T cell activation  defense response to virus  defense response to virus  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway   
NDEx NetworkIFNL2
Atlas of Cancer Signalling NetworkIFNL2
Wikipedia pathwaysIFNL2
Orthology - Evolution
OrthoDB282616
GeneTree (enSembl)ENSG00000183709
Phylogenetic Trees/Animal Genes : TreeFamIFNL2
HOVERGENQ8IZJ0
HOGENOMQ8IZJ0
Homologs : HomoloGeneIFNL2
Homology/Alignments : Family Browser (UCSC)IFNL2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFNL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFNL2
dbVarIFNL2
ClinVarIFNL2
1000_GenomesIFNL2 
Exome Variant ServerIFNL2
ExAC (Exome Aggregation Consortium)IFNL2 (select the gene name)
Genetic variants : HAPMAP282616
Genomic Variants (DGV)IFNL2 [DGVbeta]
DECIPHERIFNL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFNL2 
Mutations
ICGC Data PortalIFNL2 
TCGA Data PortalIFNL2 
Broad Tumor PortalIFNL2
OASIS PortalIFNL2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIFNL2
BioMutasearch IFNL2
DgiDB (Drug Gene Interaction Database)IFNL2
DoCM (Curated mutations)IFNL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFNL2 (select a term)
intoGenIFNL2
Cancer3DIFNL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607401   
Orphanet
MedgenIFNL2
Genetic Testing Registry IFNL2
NextProtQ8IZJ0 [Medical]
TSGene282616
GENETestsIFNL2
Target ValidationIFNL2
Huge Navigator IFNL2 [HugePedia]
snp3D : Map Gene to Disease282616
BioCentury BCIQIFNL2
ClinGenIFNL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD282616
Chemical/Pharm GKB GenePA134934396
Clinical trialIFNL2
Miscellaneous
canSAR (ICR)IFNL2 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFNL2
EVEXIFNL2
GoPubMedIFNL2
iHOPIFNL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:56:04 CEST 2017

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