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IFNL4 (interferon lambda 4 (gene/pseudogene))

Identity

Alias_symbol (synonym)IFNAN
Other alias
HGNC (Hugo) IFNL4
LocusID (NCBI) 101180976
Atlas_Id 56497
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 39246314 and ends at 39248856 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFNL4   44480
Cards
Entrez_Gene (NCBI)IFNL4  101180976  interferon lambda 4 (gene/pseudogene)
AliasesIFNAN
GeneCards (Weizmann)IFNL4
Ensembl hg19 (Hinxton)ENSG00000272395 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000272395 [Gene_View]  chr19:39246314-39248856 [Contig_View]  IFNL4 [Vega]
ICGC DataPortalENSG00000272395
TCGA cBioPortalIFNL4
AceView (NCBI)IFNL4
Genatlas (Paris)IFNL4
WikiGenes101180976
SOURCE (Princeton)IFNL4
Genetics Home Reference (NIH)IFNL4
Genomic and cartography
GoldenPath hg38 (UCSC)IFNL4  -     chr19:39246314-39248856 -  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFNL4  -     19q13.2   [Description]    (hg19-Feb_2009)
EnsemblIFNL4 - 19q13.2 [CytoView hg19]  IFNL4 - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBIIFNL4 [Mapview hg19]  IFNL4 [Mapview hg38]
OMIM615090   
Gene and transcription
Genbank (Entrez)JN806225 JN806226 JN806227 JN806228 JN806229
RefSeq transcript (Entrez)NM_001276254
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFNL4
Cluster EST : UnigeneHs.745579 [ NCBI ]
CGAP (NCI)Hs.745579
Alternative Splicing GalleryENSG00000272395
Gene ExpressionIFNL4 [ NCBI-GEO ]   IFNL4 [ EBI - ARRAY_EXPRESS ]   IFNL4 [ SEEK ]   IFNL4 [ MEM ]
Gene Expression Viewer (FireBrowse)IFNL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)101180976
GTEX Portal (Tissue expression)IFNL4
Human Protein AtlasENSG00000272395-IFNL4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtK9M1U5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtK9M1U5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProK9M1U5
Splice isoforms : SwissVarK9M1U5
PhosPhoSitePlusK9M1U5
Domains : Interpro (EBI)INF_lambda   
Domain families : Pfam (Sanger)IL28A (PF15177)   
Domain families : Pfam (NCBI)pfam15177   
Conserved Domain (NCBI)IFNL4
DMDM Disease mutations101180976
Blocks (Seattle)IFNL4
SuperfamilyK9M1U5
Human Protein Atlas [tissue]ENSG00000272395-IFNL4 [tissue]
Peptide AtlasK9M1U5
Protein Interaction databases
DIP (DOE-UCLA)K9M1U5
IntAct (EBI)K9M1U5
FunCoupENSG00000272395
BioGRIDIFNL4
STRING (EMBL)IFNL4
ZODIACIFNL4
Ontologies - Pathways
QuickGOK9M1U5
Ontology : AmiGOcytokine activity  extracellular space  cytoplasm  innate immune response  positive regulation of immune response  regulation of T cell activation  defense response to virus  
Ontology : EGO-EBIcytokine activity  extracellular space  cytoplasm  innate immune response  positive regulation of immune response  regulation of T cell activation  defense response to virus  
NDEx NetworkIFNL4
Atlas of Cancer Signalling NetworkIFNL4
Wikipedia pathwaysIFNL4
Orthology - Evolution
OrthoDB101180976
GeneTree (enSembl)ENSG00000272395
Phylogenetic Trees/Animal Genes : TreeFamIFNL4
HOVERGENK9M1U5
HOGENOMK9M1U5
Homologs : HomoloGeneIFNL4
Homology/Alignments : Family Browser (UCSC)IFNL4
Gene fusions - Rearrangements
Tumor Fusion PortalIFNL4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFNL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFNL4
dbVarIFNL4
ClinVarIFNL4
1000_GenomesIFNL4 
Exome Variant ServerIFNL4
ExAC (Exome Aggregation Consortium)ENSG00000272395
GNOMAD BrowserENSG00000272395
Genetic variants : HAPMAP101180976
Genomic Variants (DGV)IFNL4 [DGVbeta]
DECIPHERIFNL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFNL4 
Mutations
ICGC Data PortalIFNL4 
TCGA Data PortalIFNL4 
Broad Tumor PortalIFNL4
OASIS PortalIFNL4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIFNL4
BioMutasearch IFNL4
DgiDB (Drug Gene Interaction Database)IFNL4
DoCM (Curated mutations)IFNL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFNL4 (select a term)
intoGenIFNL4
Cancer3DIFNL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615090   
Orphanet20569   
DisGeNETIFNL4
MedgenIFNL4
Genetic Testing Registry IFNL4
NextProtK9M1U5 [Medical]
TSGene101180976
GENETestsIFNL4
Target ValidationIFNL4
Huge Navigator IFNL4 [HugePedia]
snp3D : Map Gene to Disease101180976
BioCentury BCIQIFNL4
ClinGenIFNL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD101180976
Chemical/Pharm GKB GenePA166049147
Clinical trialIFNL4
Miscellaneous
canSAR (ICR)IFNL4 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFNL4
EVEXIFNL4
GoPubMedIFNL4
iHOPIFNL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:17:21 CET 2017

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