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IFT88 (intraflagellar transport 88)

Identity

Alias_namesTTC10
tetratricopeptide repeat domain 10
intraflagellar transport 88 homolog (Chlamydomonas)
Alias_symbol (synonym)hTg737
Tg737
D13S1056E
MGC26259
Other aliasDAF19
TG737
HGNC (Hugo) IFT88
LocusID (NCBI) 8100
Atlas_Id 42722
Location 13q12.11  [Link to chromosome band 13q12]
Location_base_pair Starts at 20566816 and ends at 20691437 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BRF1 (14q32.33) / IFT88 (13q12.11)ELMO1 (7p14.2) / IFT88 (13q12.11)IFT88 (13q12.11) / IFT88 (13q12.11)
IFT88 (13q12.11) / WASF3 (13q12.13)IL17D (13q12.11) / IFT88 (13q12.11)RUNX2 (6p21.1) / IFT88 (13q12.11)
XIRP1 (3p22.2) / IFT88 (13q12.11)ZMYM5 (13q12.11) / IFT88 (13q12.11)IFT88 13q12.11 / WASF3 13q12.13
IL17D 13q12.11 / IFT88 13q12.11RUNX2 6p21.1 / IFT88 13q12.11ZMYM5 13q12.11 / IFT88 13q12.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFT88   20606
Cards
Entrez_Gene (NCBI)IFT88  8100  intraflagellar transport 88
AliasesD13S1056E; DAF19; TG737; TTC10; 
hTg737
GeneCards (Weizmann)IFT88
Ensembl hg19 (Hinxton)ENSG00000032742 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000032742 [Gene_View]  chr13:20566816-20691437 [Contig_View]  IFT88 [Vega]
ICGC DataPortalENSG00000032742
TCGA cBioPortalIFT88
AceView (NCBI)IFT88
Genatlas (Paris)IFT88
WikiGenes8100
SOURCE (Princeton)IFT88
Genetics Home Reference (NIH)IFT88
Genomic and cartography
GoldenPath hg38 (UCSC)IFT88  -     chr13:20566816-20691437 +  13q12.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFT88  -     13q12.11   [Description]    (hg19-Feb_2009)
EnsemblIFT88 - 13q12.11 [CytoView hg19]  IFT88 - 13q12.11 [CytoView hg38]
Mapping of homologs : NCBIIFT88 [Mapview hg19]  IFT88 [Mapview hg38]
OMIM600595   
Gene and transcription
Genbank (Entrez)AK058172 AK126668 AK300769 AK303853 AK308281
RefSeq transcript (Entrez)NM_001318491 NM_001318493 NM_006531 NM_175605
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFT88
Cluster EST : UnigeneHs.187376 [ NCBI ]
CGAP (NCI)Hs.187376
Alternative Splicing GalleryENSG00000032742
Gene ExpressionIFT88 [ NCBI-GEO ]   IFT88 [ EBI - ARRAY_EXPRESS ]   IFT88 [ SEEK ]   IFT88 [ MEM ]
Gene Expression Viewer (FireBrowse)IFT88 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8100
GTEX Portal (Tissue expression)IFT88
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13099   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13099  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13099
Splice isoforms : SwissVarQ13099
PhosPhoSitePlusQ13099
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)Sel1-like    TPR-contain_dom    TPR-like_helical_dom    TPR_repeat   
Domain families : Pfam (Sanger)TPR_6 (PF13174)    TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam13174    pfam13181   
Domain families : Smart (EMBL)SEL1 (SM00671)  TPR (SM00028)  
Conserved Domain (NCBI)IFT88
DMDM Disease mutations8100
Blocks (Seattle)IFT88
SuperfamilyQ13099
Human Protein AtlasENSG00000032742
Peptide AtlasQ13099
HPRD09000
IPIIPI00402297   IPI00646878   IPI00973733   IPI00796368   IPI01018783   IPI00943353   IPI01013692   
Protein Interaction databases
DIP (DOE-UCLA)Q13099
IntAct (EBI)Q13099
FunCoupENSG00000032742
BioGRIDIFT88
STRING (EMBL)IFT88
ZODIACIFT88
Ontologies - Pathways
QuickGOQ13099
Ontology : AmiGOprotein binding  centriole  centriole  cilium  cilium  cilium  intraciliary transport particle B  motile cilium  intraciliary transport involved in cilium assembly  ciliary basal body  cilium assembly  ciliary tip  regulation of cilium assembly  regulation of autophagosome assembly  
Ontology : EGO-EBIprotein binding  centriole  centriole  cilium  cilium  cilium  intraciliary transport particle B  motile cilium  intraciliary transport involved in cilium assembly  ciliary basal body  cilium assembly  ciliary tip  regulation of cilium assembly  regulation of autophagosome assembly  
NDEx NetworkIFT88
Atlas of Cancer Signalling NetworkIFT88
Wikipedia pathwaysIFT88
Orthology - Evolution
OrthoDB8100
GeneTree (enSembl)ENSG00000032742
Phylogenetic Trees/Animal Genes : TreeFamIFT88
HOVERGENQ13099
HOGENOMQ13099
Homologs : HomoloGeneIFT88
Homology/Alignments : Family Browser (UCSC)IFT88
Gene fusions - Rearrangements
Fusion : MitelmanIFT88/WASF3 [13q12.11/13q12.13]  
Fusion : MitelmanIL17D/IFT88 [13q12.11/13q12.11]  [t(13;13)(q12;q12)]  
Fusion : MitelmanRUNX2/IFT88 [6p21.1/13q12.11]  [t(6;13)(p21;q12)]  
Fusion : MitelmanZMYM5/IFT88 [13q12.11/13q12.11]  [t(13;13)(q12;q12)]  
Fusion: TCGAIFT88 13q12.11 WASF3 13q12.13 BRCA
Fusion: TCGAIL17D 13q12.11 IFT88 13q12.11 SKCM
Fusion: TCGARUNX2 6p21.1 IFT88 13q12.11 BRCA
Fusion: TCGAZMYM5 13q12.11 IFT88 13q12.11 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFT88 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFT88
dbVarIFT88
ClinVarIFT88
1000_GenomesIFT88 
Exome Variant ServerIFT88
ExAC (Exome Aggregation Consortium)IFT88 (select the gene name)
Genetic variants : HAPMAP8100
Genomic Variants (DGV)IFT88 [DGVbeta]
DECIPHERIFT88 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFT88 
Mutations
ICGC Data PortalIFT88 
TCGA Data PortalIFT88 
Broad Tumor PortalIFT88
OASIS PortalIFT88 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFT88  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFT88
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFT88
DgiDB (Drug Gene Interaction Database)IFT88
DoCM (Curated mutations)IFT88 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFT88 (select a term)
intoGenIFT88
Cancer3DIFT88(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600595   
Orphanet
MedgenIFT88
Genetic Testing Registry IFT88
NextProtQ13099 [Medical]
TSGene8100
GENETestsIFT88
Target ValidationIFT88
Huge Navigator IFT88 [HugePedia]
snp3D : Map Gene to Disease8100
BioCentury BCIQIFT88
ClinGenIFT88
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8100
Chemical/Pharm GKB GenePA134991804
Clinical trialIFT88
Miscellaneous
canSAR (ICR)IFT88 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFT88
EVEXIFT88
GoPubMedIFT88
iHOPIFT88
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:03:46 CEST 2017

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