Atlas of Genetics and Cytogenetics in Oncology and Haematology

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IGF2 (insulin like growth factor 2)


Alias (NCBI)C11orf43
HGNC (Hugo) IGF2
HGNC Alias symbFLJ44734
HGNC Alias namesomatomedin A
HGNC Previous nameC11orf43
HGNC Previous namechromosome 11 open reading frame 43
 insulin-like growth factor 2
LocusID (NCBI) 3481
Atlas_Id 159
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 2129117 and ends at 2140943 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C5orf45 (5q35.3) / IGF2 (11p15.5)CTNNA3 (10q21.3) / IGF2 (11p15.5)IGF2 (11p15.5) / AP1G2 (14q11.2)
IGF2 (11p15.5) / CTNNA3 (10q21.3)IGF2 (11p15.5) / INS (11p15.5)IGF2 (11p15.5) / MCM8 (20p12.3)
IGF2 (11p15.5) / PLXNA1 (3q21.3)IGF2 (11p15.5) / SNW1 (14q24.3)INS-IGF2 (11p15.5) / IGF2 (11p15.5)
MALAT1 (11q13.1) / IGF2 (11p15.5)RPAP1 (15q15.1) / IGF2 (11p15.5)IGF2 11p15.5 / AP1G2 14q11.2
IGF2 11p15.5 / MCM8 20p12.3IGF2 11p15.5 / SNW1 14q24.3


Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Beckwith-Wiedemann syndrome

External links

HGNC (Hugo)IGF2   5466
LRG (Locus Reference Genomic)LRG_1031
Entrez_Gene (NCBI)IGF2    insulin like growth factor 2
AliasesC11orf43; GRDF; IGF-II; PP9974; 
GeneCards (Weizmann)IGF2
Ensembl hg19 (Hinxton)ENSG00000167244 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167244 [Gene_View]  ENSG00000167244 [Sequence]  chr11:2129117-2140943 [Contig_View]  IGF2 [Vega]
ICGC DataPortalENSG00000167244
TCGA cBioPortalIGF2
AceView (NCBI)IGF2
Genatlas (Paris)IGF2
SOURCE (Princeton)IGF2
Genetics Home Reference (NIH)IGF2
Genomic and cartography
GoldenPath hg38 (UCSC)IGF2  -     chr11:2129117-2140943 -  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IGF2  -     11p15.5   [Description]    (hg19-Feb_2009)
GoldenPathIGF2 - 11p15.5 [CytoView hg19]  IGF2 - 11p15.5 [CytoView hg38]
genome Data Viewer NCBIIGF2 [Mapview hg19]  
OMIM130650   147470   180860   194070   616489   
Gene and transcription
Genbank (Entrez)AA040827 AF318382 AK025719 AK074614 AK126688
RefSeq transcript (Entrez)NM_000612 NM_001007139 NM_001127598 NM_001291861 NM_001291862
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IGF2
Alternative Splicing GalleryENSG00000167244
Gene ExpressionIGF2 [ NCBI-GEO ]   IGF2 [ EBI - ARRAY_EXPRESS ]   IGF2 [ SEEK ]   IGF2 [ MEM ]
Gene Expression Viewer (FireBrowse)IGF2 [ Firebrowse - Broad ]
GenevisibleExpression of IGF2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3481
GTEX Portal (Tissue expression)IGF2
Human Protein AtlasENSG00000167244-IGF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)IGF2
Blocks (Seattle)IGF2
Human Protein Atlas [tissue]ENSG00000167244-IGF2 [tissue]
IPIIPI00001508   IPI00001611   IPI00940065   IPI00215977   IPI00853573   IPI00894133   IPI00853225   
Protein Interaction databases
Ontologies - Pathways
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:26:16 CET 2021

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