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IGF2 (insulin like growth factor 2)

Identity

Alias (NCBI)C11orf43
GRDF
IGF-II
PP9974
SRS3
HGNC (Hugo) IGF2
HGNC Alias symbFLJ44734
IGF-II
HGNC Alias namesomatomedin A
 preptin
HGNC Previous nameC11orf43
HGNC Previous namechromosome 11 open reading frame 43
 insulin-like growth factor 2
LocusID (NCBI) 3481
Atlas_Id 159
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 2129117 and ends at 2140943 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C5orf45 (5q35.3) / IGF2 (11p15.5)CTNNA3 (10q21.3) / IGF2 (11p15.5)IGF2 (11p15.5) / AP1G2 (14q11.2)
IGF2 (11p15.5) / CTNNA3 (10q21.3)IGF2 (11p15.5) / INS (11p15.5)IGF2 (11p15.5) / MCM8 (20p12.3)
IGF2 (11p15.5) / PLXNA1 (3q21.3)IGF2 (11p15.5) / SNW1 (14q24.3)INS-IGF2 (11p15.5) / IGF2 (11p15.5)
MALAT1 (11q13.1) / IGF2 (11p15.5)RPAP1 (15q15.1) / IGF2 (11p15.5)IGF2 11p15.5 / AP1G2 14q11.2
IGF2 11p15.5 / MCM8 20p12.3IGF2 11p15.5 / SNW1 14q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Beckwith-Wiedemann syndrome

External links

Nomenclature
HGNC (Hugo)IGF2   5466
LRG (Locus Reference Genomic)LRG_1031
Cards
Entrez_Gene (NCBI)IGF2    insulin like growth factor 2
AliasesC11orf43; GRDF; IGF-II; PP9974; 
SRS3
GeneCards (Weizmann)IGF2
Ensembl hg19 (Hinxton)ENSG00000167244 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167244 [Gene_View]  ENSG00000167244 [Sequence]  chr11:2129117-2140943 [Contig_View]  IGF2 [Vega]
ICGC DataPortalENSG00000167244
TCGA cBioPortalIGF2
AceView (NCBI)IGF2
Genatlas (Paris)IGF2
SOURCE (Princeton)IGF2
Genetics Home Reference (NIH)IGF2
Genomic and cartography
GoldenPath hg38 (UCSC)IGF2  -     chr11:2129117-2140943 -  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IGF2  -     11p15.5   [Description]    (hg19-Feb_2009)
GoldenPathIGF2 - 11p15.5 [CytoView hg19]  IGF2 - 11p15.5 [CytoView hg38]
ImmunoBaseENSG00000167244
genome Data Viewer NCBIIGF2 [Mapview hg19]  
OMIM130650   147470   180860   194070   616489   
Gene and transcription
Genbank (Entrez)AA040827 AF318382 AK025719 AK074614 AK126688
RefSeq transcript (Entrez)NM_000612 NM_001007139 NM_001127598 NM_001291861 NM_001291862
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IGF2
Alternative Splicing GalleryENSG00000167244
Gene ExpressionIGF2 [ NCBI-GEO ]   IGF2 [ EBI - ARRAY_EXPRESS ]   IGF2 [ SEEK ]   IGF2 [ MEM ]
Gene Expression Viewer (FireBrowse)IGF2 [ Firebrowse - Broad ]
GenevisibleExpression of IGF2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3481
GTEX Portal (Tissue expression)IGF2
Human Protein AtlasENSG00000167244-IGF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)IGF2
Blocks (Seattle)IGF2
Human Protein Atlas [tissue]ENSG00000167244-IGF2 [tissue]
HPRD00939
IPIIPI00001508   IPI00001611   IPI00940065   IPI00215977   IPI00853573   IPI00894133   IPI00853225   
Protein Interaction databases
BioGRIDIGF2
STRING (EMBL)IGF2
ZODIACIGF2
Ontologies - Pathways
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIGF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 25 19:26:16 CET 2021
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