IGHA1 (immunoglobulin heavy constant alpha 1)

2013-05-01  

Identity

HGNC
LOCATION
14q32.33
LOCUSID
ALIAS
IgA1
FUSION GENES

Other Information

Locus ID:

NCBI: 3493
MIM: 146900
HGNC: 5478
Ensembl: ENSG00000211895
IMGT/GENE-DB:

Variants:

dbSNP: 3493
ClinVar: 3493
TCGA: ENSG00000211895
COSMIC: IGHA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000211895ENST00000390547P01876
ENSG00000211895ENST00000641837A0A286YEY1

Expression (GTEx)

0
5000
10000
15000

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Vesicle-mediated transportREACTOMER-HSA-5653656
Binding and Uptake of Ligands by Scavenger ReceptorsREACTOMER-HSA-2173782
Scavenging of heme from plasmaREACTOMER-HSA-2168880

References

Pubmed IDYearTitleCitations
378069742024Porphyromonas gingivalis infection in the oral cavity is associated with elevated galactose-deficient IgA1 and increased nephritis severity in IgA nephropathy.0
386229292024The transcription factor HMGB2 indirectly regulates APRIL expression and Gd-IgA1 production in patients with IgA nephropathy.0
386739682024Insight into the Interplay of Gd-IgA1, HMGB1, RAGE and PCDH1 in IgA Vasculitis (IgAV).0
378069742024Porphyromonas gingivalis infection in the oral cavity is associated with elevated galactose-deficient IgA1 and increased nephritis severity in IgA nephropathy.0
386229292024The transcription factor HMGB2 indirectly regulates APRIL expression and Gd-IgA1 production in patients with IgA nephropathy.0
386739682024Insight into the Interplay of Gd-IgA1, HMGB1, RAGE and PCDH1 in IgA Vasculitis (IgAV).0
362889812023Galactose-deficient IgA1 Is Involved in IgA Deposition in Renal Grafts Biopsied One Hour after Kidney Transplantation.1
362889812023Galactose-deficient IgA1 Is Involved in IgA Deposition in Renal Grafts Biopsied One Hour after Kidney Transplantation.1
331220532021CD71 mesangial IgA1 receptor and the progression of IgA nephropathy.6
333418012021Elevated Endostatin Expression Is Regulated by the pIgA Immune Complex and Associated with Disease Severity of IgA Nephropathy.3
335789172021Detailed Structure and Pathophysiological Roles of the IgA-Albumin Complex in Multiple Myeloma.1
336087722021Aberrant RL2 O-GlcNAc antibody reactivity against serum-IgA1 of patients with colorectal cancer.3
331220532021CD71 mesangial IgA1 receptor and the progression of IgA nephropathy.6
333418012021Elevated Endostatin Expression Is Regulated by the pIgA Immune Complex and Associated with Disease Severity of IgA Nephropathy.3
335789172021Detailed Structure and Pathophysiological Roles of the IgA-Albumin Complex in Multiple Myeloma.1

Citation

Dessen P

IGHA1 (immunoglobulin heavy constant alpha 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53263/igha1