Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IGHE (immunoglobulin heavy constant epsilon)

Identity

Other aliasIgE
HGNC (Hugo) IGHE
LocusID (NCBI) 3497
Atlas_Id 52095
Location 14q32.33  [Link to chromosome band 14q32]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)IGHE   5522
Cards
Entrez_Gene (NCBI)IGHE  3497  immunoglobulin heavy constant epsilon
AliasesIgE
GeneCards (Weizmann)IGHE
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  - [Contig_View]  IGHE [Vega]
TCGA cBioPortalIGHE
AceView (NCBI)IGHE
Genatlas (Paris)IGHE
WikiGenes3497
SOURCE (Princeton)IGHE
Genetics Home Reference (NIH)IGHE
Genomic and cartography
GoldenPath hg38 (UCSC)IGHE  -  
GoldenPath hg19 (UCSC)IGHE  -  
EnsemblIGHE - [CytoView hg19]  IGHE - [CytoView hg38]
Mapping of homologs : NCBIIGHE [Mapview hg19]  IGHE [Mapview hg38]
OMIM147180   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_001019 NT_187600
Consensus coding sequences : CCDS (NCBI)IGHE
Gene ExpressionIGHE [ NCBI-GEO ]   IGHE [ EBI - ARRAY_EXPRESS ]   IGHE [ SEEK ]   IGHE [ MEM ]
Gene Expression Viewer (FireBrowse)IGHE [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3497
GTEX Portal (Tissue expression)IGHE
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01854   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01854  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01854
Splice isoforms : SwissVarP01854
PhosPhoSitePlusP01854
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_C1-set   
Domain families : Pfam (Sanger)C1-set (PF07654)   
Domain families : Pfam (NCBI)pfam07654   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)IGHE
DMDM Disease mutations3497
Blocks (Seattle)IGHE
PDB (SRS)1F6A    1FP5    1G84    1IGE    1O0V    2WQR    2Y7Q    3H9Y    3H9Z    3HA0    4EZM    4GKO    4GRG    4GT7    4J4P    4KI1    5ANM    5HYS   
PDB (PDBSum)1F6A    1FP5    1G84    1IGE    1O0V    2WQR    2Y7Q    3H9Y    3H9Z    3HA0    4EZM    4GKO    4GRG    4GT7    4J4P    4KI1    5ANM    5HYS   
PDB (IMB)1F6A    1FP5    1G84    1IGE    1O0V    2WQR    2Y7Q    3H9Y    3H9Z    3HA0    4EZM    4GKO    4GRG    4GT7    4J4P    4KI1    5ANM    5HYS   
PDB (RSDB)1F6A    1FP5    1G84    1IGE    1O0V    2WQR    2Y7Q    3H9Y    3H9Z    3HA0    4EZM    4GKO    4GRG    4GT7    4J4P    4KI1    5ANM    5HYS   
Structural Biology KnowledgeBase1F6A    1FP5    1G84    1IGE    1O0V    2WQR    2Y7Q    3H9Y    3H9Z    3HA0    4EZM    4GKO    4GRG    4GT7    4J4P    4KI1    5ANM    5HYS   
SCOP (Structural Classification of Proteins)1F6A    1FP5    1G84    1IGE    1O0V    2WQR    2Y7Q    3H9Y    3H9Z    3HA0    4EZM    4GKO    4GRG    4GT7    4J4P    4KI1    5ANM    5HYS   
CATH (Classification of proteins structures)1F6A    1FP5    1G84    1IGE    1O0V    2WQR    2Y7Q    3H9Y    3H9Z    3HA0    4EZM    4GKO    4GRG    4GT7    4J4P    4KI1    5ANM    5HYS   
SuperfamilyP01854
Peptide AtlasP01854
IPIIPI00399005   
Protein Interaction databases
DIP (DOE-UCLA)P01854
IntAct (EBI)P01854
BioGRIDIGHE
STRING (EMBL)IGHE
ZODIACIGHE
Ontologies - Pathways
QuickGOP01854
Ontology : AmiGOantigen binding  antigen binding  extracellular region  phagocytosis, recognition  phagocytosis, engulfment  immune response  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-epsilon receptor signaling pathway  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  blood microparticle  
Ontology : EGO-EBIantigen binding  antigen binding  extracellular region  phagocytosis, recognition  phagocytosis, engulfment  immune response  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-epsilon receptor signaling pathway  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  blood microparticle  
NDEx NetworkIGHE
Atlas of Cancer Signalling NetworkIGHE
Wikipedia pathwaysIGHE
Orthology - Evolution
OrthoDB3497
Phylogenetic Trees/Animal Genes : TreeFamIGHE
HOVERGENP01854
HOGENOMP01854
Homologs : HomoloGeneIGHE
Homology/Alignments : Family Browser (UCSC)IGHE
Gene fusions - Rearrangements
Tumor Fusion PortalIGHE
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIGHE [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IGHE
dbVarIGHE
ClinVarIGHE
1000_GenomesIGHE 
Exome Variant ServerIGHE
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP3497
Genomic Variants (DGV)IGHE [DGVbeta]
DECIPHERIGHE [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIGHE 
Mutations
ICGC Data PortalIGHE 
TCGA Data PortalIGHE 
Broad Tumor PortalIGHE
OASIS PortalIGHE [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIGHE
BioMutasearch IGHE
DgiDB (Drug Gene Interaction Database)IGHE
DoCM (Curated mutations)IGHE (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IGHE (select a term)
intoGenIGHE
Cancer3DIGHE(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147180   
Orphanet
DisGeNETIGHE
MedgenIGHE
Genetic Testing Registry IGHE
NextProtP01854 [Medical]
TSGene3497
GENETestsIGHE
Target ValidationIGHE
Huge Navigator IGHE [HugePedia]
snp3D : Map Gene to Disease3497
BioCentury BCIQIGHE
ClinGenIGHE
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3497
Chemical/Pharm GKB GenePA29713
Clinical trialIGHE
Miscellaneous
canSAR (ICR)IGHE (select the gene name)
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIGHE
EVEXIGHE
GoPubMedIGHE
iHOPIGHE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:17:29 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.