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IGHG1 (immunoglobulin heavy constant gamma 1 (G1m marker))

Identity

Other alias-
HGNC (Hugo) IGHG1
LocusID (NCBI) 3500
Atlas_Id 52481
Location 14_KI270846v1_alt  [Link to chromosome band 14]
Location_base_pair Starts at 209246 and ends at 210832 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACTB (7p22.1) / IGHG1 (14q32.33)CCND1 (11q13.3) / IGHG1 (14q32.33)CD74 (5q32) / IGHG1 (14q32.33)
FGFR3 (4p16.3) / IGHG1 (14q32.33)HLA-A (6p22.1) / IGHG1 (14q32.33)IGHG1 (14q32.33) / BCL10 (1p22.3)
IGHG1 (14q32.33) / BCL11A (2p16.1)IGHG1 (14q32.33) / BCL2 (18q21.33)IGHG1 (14q32.33) / BCL3 (19q13.32)
IGHG1 (14q32.33) / BCL6 (3q27.3)IGHG1 (14q32.33) / BCL6BCL9 ()IGHG1 (14q32.33) / CCND1 (11q13.3)
IGHG1 (14q32.33) / CCND2 (12p13.32)IGHG1 (14q32.33) / CCND3 (6p21.1)IGHG1 (14q32.33) / CDK6 (7q21.2)
IGHG1 (14q32.33) / CEBPA (19q13.11)IGHG1 (14q32.33) / CEBPB (20q13.13)IGHG1 (14q32.33) / CEBPD (8q11.21)
IGHG1 (14q32.33) / CEBPE (14q11.2)IGHG1 (14q32.33) / CEBPG (19q13.11)IGHG1 (14q32.33) / CHST11 (12q23.3)
IGHG1 (14q32.33) / CNN3 (1p21.3)IGHG1 (14q32.33) / DDX6 (11q23.3)IGHG1 (14q32.33) / ERVW-1 ()
IGHG1 (14q32.33) / ETV6 (12p13.2)IGHG1 (14q32.33) / FCGR2B (1q23.3)IGHG1 (14q32.33) / FCRL4 (1q23.1)
IGHG1 (14q32.33) / FGFR3 (4p16.3)IGHG1 (14q32.33) / FOXP1 (3p13)IGHG1 (14q32.33) / ID4 (6p22.3)
IGHG1 (14q32.33) / IGLL5 (22q11.22)IGHG1 (14q32.33) / IL3 (5q31.1)IGHG1 (14q32.33) / IRF4 (6p25.3)
IGHG1 (14q32.33) / KDM4C (9p24.1)IGHG1 (14q32.33) / LHX4 (1q25.2)IGHG1 (14q32.33) / MAF (16q23.2)
IGHG1 (14q32.33) / MAFB (20q12)IGHG1 (14q32.33) / MALT1 (18q21.32)IGHG1 (14q32.33) / MUC1 (1q22)
IGHG1 (14q32.33) / MYC (8q24.21)IGHG1 (14q32.33) / MYCN (2p24.3)IGHG1 (14q32.33) / NFKB2 (10q24.32)
IGHG1 (14q32.33) / PAFAH1B2 (11q23.3)IGHG1 (14q32.33) / PAX5 (9p13.2)IGHG1 (14q32.33) / PCSK7 (11q23.3)
IGHG1 (14q32.33) / RHOH (4p14)IGHG1 (14q32.33) / SPIB (19q13.33)IGHG1 (14q32.33) / TENM2 (5q34)
IGHG1 (14q32.33) / WHSC1 (4p16.3)IGHV3OR16-6 () / IGHG1 (14q32.33)IGKC (2p11.2) / IGHG1 (14q32.33)
IGKV3-11 () / IGHG1 (14q32.33)IGKV3-20 (2p11.2) / IGHG1 (14q32.33)IGLC2 () / IGHG1 (14q32.33)
IGLC3 () / IGHG1 (14q32.33)LHX4 (1q25.2) / IGHG1 (14q32.33)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)IGHG1   5525
Cards
Entrez_Gene (NCBI)IGHG1  3500  immunoglobulin heavy constant gamma 1 (G1m marker)
Aliases
GeneCards (Weizmann)IGHG1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr14_KI270846v1_alt:209246-210832 [Contig_View]  IGHG1 [Vega]
TCGA cBioPortalIGHG1
AceView (NCBI)IGHG1
Genatlas (Paris)IGHG1
WikiGenes3500
SOURCE (Princeton)IGHG1
Genetics Home Reference (NIH)IGHG1
Genomic and cartography
GoldenPath hg38 (UCSC)IGHG1  -     chr14_KI270846v1_alt:209246-210832 -  14_KI270846v1_alt   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IGHG1  -     14_KI270846v1_alt   [Description]    (hg19-Feb_2009)
EnsemblIGHG1 - 14_KI270846v1_alt [CytoView hg19]  IGHG1 - 14_KI270846v1_alt [CytoView hg38]
Mapping of homologs : NCBIIGHG1 [Mapview hg19]  IGHG1 [Mapview hg38]
OMIM147100   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)NC_000014 NG_001019 NT_187600
Consensus coding sequences : CCDS (NCBI)IGHG1
Cluster EST : UnigeneHs.510635 [ NCBI ]
CGAP (NCI)Hs.510635
Gene ExpressionIGHG1 [ NCBI-GEO ]   IGHG1 [ EBI - ARRAY_EXPRESS ]   IGHG1 [ SEEK ]   IGHG1 [ MEM ]
Gene Expression Viewer (FireBrowse)IGHG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3500
GTEX Portal (Tissue expression)IGHG1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01857   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01857  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01857
Splice isoforms : SwissVarP01857
PhosPhoSitePlusP01857
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_C1-set   
Domain families : Pfam (Sanger)C1-set (PF07654)   
Domain families : Pfam (NCBI)pfam07654   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)IGHG1
DMDM Disease mutations3500
Blocks (Seattle)IGHG1
PDB (SRS)###############################################################################################################################################################################################################################################################   
PDB (PDBSum)###############################################################################################################################################################################################################################################################   
PDB (IMB)###############################################################################################################################################################################################################################################################   
PDB (RSDB)###############################################################################################################################################################################################################################################################   
Structural Biology KnowledgeBase###############################################################################################################################################################################################################################################################   
SCOP (Structural Classification of Proteins)###############################################################################################################################################################################################################################################################   
CATH (Classification of proteins structures)###############################################################################################################################################################################################################################################################   
SuperfamilyP01857
Peptide AtlasP01857
Protein Interaction databases
DIP (DOE-UCLA)P01857
IntAct (EBI)P01857
BioGRIDIGHG1
STRING (EMBL)IGHG1
ZODIACIGHG1
Ontologies - Pathways
QuickGOP01857
Ontology : AmiGOantigen binding  serine-type endopeptidase activity  protein binding  extracellular region  extracellular space  proteolysis  phagocytosis, recognition  phagocytosis, engulfment  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  extracellular exosome  blood microparticle  
Ontology : EGO-EBIantigen binding  serine-type endopeptidase activity  protein binding  extracellular region  extracellular space  proteolysis  phagocytosis, recognition  phagocytosis, engulfment  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  extracellular exosome  blood microparticle  
NDEx NetworkIGHG1
Atlas of Cancer Signalling NetworkIGHG1
Wikipedia pathwaysIGHG1
Orthology - Evolution
OrthoDB3500
Phylogenetic Trees/Animal Genes : TreeFamIGHG1
HOVERGENP01857
HOGENOMP01857
Homologs : HomoloGeneIGHG1
Homology/Alignments : Family Browser (UCSC)IGHG1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIGHG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IGHG1
dbVarIGHG1
ClinVarIGHG1
1000_GenomesIGHG1 
Exome Variant ServerIGHG1
ExAC (Exome Aggregation Consortium)IGHG1 (select the gene name)
Genetic variants : HAPMAP3500
Genomic Variants (DGV)IGHG1 [DGVbeta]
DECIPHERIGHG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIGHG1 
Mutations
ICGC Data PortalIGHG1 
TCGA Data PortalIGHG1 
Broad Tumor PortalIGHG1
OASIS PortalIGHG1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIGHG1
BioMutasearch IGHG1
DgiDB (Drug Gene Interaction Database)IGHG1
DoCM (Curated mutations)IGHG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IGHG1 (select a term)
intoGenIGHG1
Cancer3DIGHG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147100   
Orphanet10899   
MedgenIGHG1
Genetic Testing Registry IGHG1
NextProtP01857 [Medical]
TSGene3500
GENETestsIGHG1
Target ValidationIGHG1
Huge Navigator IGHG1 [HugePedia]
snp3D : Map Gene to Disease3500
BioCentury BCIQIGHG1
ClinGenIGHG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3500
Chemical/Pharm GKB GenePA29716
Clinical trialIGHG1
Miscellaneous
canSAR (ICR)IGHG1 (select the gene name)
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIGHG1
EVEXIGHG1
GoPubMedIGHG1
iHOPIGHG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:03:49 CEST 2017

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