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IGHG2 (immunoglobulin heavy constant gamma 2 (G2m marker))

Identity

Other alias-
HGNC (Hugo) IGHG2
LocusID (NCBI) 3501
Atlas_Id 64548
Location 14_KI270846v1_alt  [Link to chromosome band 14]
Location_base_pair Starts at 110976 and ends at 112551 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IGKC (2p11.2) / IGHG2 (14q32.33)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)IGHG2   5526
Cards
Entrez_Gene (NCBI)IGHG2  3501  immunoglobulin heavy constant gamma 2 (G2m marker)
Aliases
GeneCards (Weizmann)IGHG2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr14_KI270846v1_alt:110976-112551 [Contig_View]  IGHG2 [Vega]
TCGA cBioPortalIGHG2
AceView (NCBI)IGHG2
Genatlas (Paris)IGHG2
WikiGenes3501
SOURCE (Princeton)IGHG2
Genetics Home Reference (NIH)IGHG2
Genomic and cartography
GoldenPath hg38 (UCSC)IGHG2  -     chr14_KI270846v1_alt:110976-112551 -  14_KI270846v1_alt   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IGHG2  -     14_KI270846v1_alt   [Description]    (hg19-Feb_2009)
EnsemblIGHG2 - 14_KI270846v1_alt [CytoView hg19]  IGHG2 - 14_KI270846v1_alt [CytoView hg38]
Mapping of homologs : NCBIIGHG2 [Mapview hg19]  IGHG2 [Mapview hg38]
OMIM147110   
Gene and transcription
Genbank (Entrez)AJ294731 BC040042 BC062335 BX640623 CR749861
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_001019 NT_187600
Consensus coding sequences : CCDS (NCBI)IGHG2
Cluster EST : UnigeneHs.510635 [ NCBI ]
CGAP (NCI)Hs.510635
Gene ExpressionIGHG2 [ NCBI-GEO ]   IGHG2 [ EBI - ARRAY_EXPRESS ]   IGHG2 [ SEEK ]   IGHG2 [ MEM ]
Gene Expression Viewer (FireBrowse)IGHG2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3501
GTEX Portal (Tissue expression)IGHG2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01859   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01859  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01859
Splice isoforms : SwissVarP01859
PhosPhoSitePlusP01859
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_C1-set   
Domain families : Pfam (Sanger)C1-set (PF07654)   
Domain families : Pfam (NCBI)pfam07654   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)IGHG2
DMDM Disease mutations3501
Blocks (Seattle)IGHG2
PDB (SRS)2QSC    4HAF    4HAG    4L4J   
PDB (PDBSum)2QSC    4HAF    4HAG    4L4J   
PDB (IMB)2QSC    4HAF    4HAG    4L4J   
PDB (RSDB)2QSC    4HAF    4HAG    4L4J   
Structural Biology KnowledgeBase2QSC    4HAF    4HAG    4L4J   
SCOP (Structural Classification of Proteins)2QSC    4HAF    4HAG    4L4J   
CATH (Classification of proteins structures)2QSC    4HAF    4HAG    4L4J   
SuperfamilyP01859
Peptide AtlasP01859
IPIIPI00930072   IPI00426051   IPI00399007   
Protein Interaction databases
DIP (DOE-UCLA)P01859
IntAct (EBI)P01859
BioGRIDIGHG2
STRING (EMBL)IGHG2
ZODIACIGHG2
Ontologies - Pathways
QuickGOP01859
Ontology : AmiGOantigen binding  serine-type endopeptidase activity  protein binding  extracellular region  extracellular space  proteolysis  phagocytosis, recognition  phagocytosis, engulfment  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  extracellular exosome  blood microparticle  
Ontology : EGO-EBIantigen binding  serine-type endopeptidase activity  protein binding  extracellular region  extracellular space  proteolysis  phagocytosis, recognition  phagocytosis, engulfment  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  extracellular exosome  blood microparticle  
NDEx NetworkIGHG2
Atlas of Cancer Signalling NetworkIGHG2
Wikipedia pathwaysIGHG2
Orthology - Evolution
OrthoDB3501
Phylogenetic Trees/Animal Genes : TreeFamIGHG2
HOVERGENP01859
HOGENOMP01859
Homologs : HomoloGeneIGHG2
Homology/Alignments : Family Browser (UCSC)IGHG2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIGHG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IGHG2
dbVarIGHG2
ClinVarIGHG2
1000_GenomesIGHG2 
Exome Variant ServerIGHG2
ExAC (Exome Aggregation Consortium)IGHG2 (select the gene name)
Genetic variants : HAPMAP3501
Genomic Variants (DGV)IGHG2 [DGVbeta]
DECIPHERIGHG2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIGHG2 
Mutations
ICGC Data PortalIGHG2 
TCGA Data PortalIGHG2 
Broad Tumor PortalIGHG2
OASIS PortalIGHG2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIGHG2
BioMutasearch IGHG2
DgiDB (Drug Gene Interaction Database)IGHG2
DoCM (Curated mutations)IGHG2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IGHG2 (select a term)
intoGenIGHG2
Cancer3DIGHG2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147110   
Orphanet18308   
MedgenIGHG2
Genetic Testing Registry IGHG2
NextProtP01859 [Medical]
TSGene3501
GENETestsIGHG2
Target ValidationIGHG2
Huge Navigator IGHG2 [HugePedia]
snp3D : Map Gene to Disease3501
BioCentury BCIQIGHG2
ClinGenIGHG2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3501
Chemical/Pharm GKB GenePA29717
Clinical trialIGHG2
Miscellaneous
canSAR (ICR)IGHG2 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIGHG2
EVEXIGHG2
GoPubMedIGHG2
iHOPIGHG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:53:13 CEST 2017

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