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IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker))

Identity

Other aliasIgG3
HGNC (Hugo) IGHG3
LocusID (NCBI) 3502
Atlas_Id 56144
Location 14_KI270846v1_alt  [Link to chromosome band 14]
Location_base_pair Starts at 236872 and ends at 852000 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IGKC (2p11.2) / IGHG3 (14q32.33)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)IGHG3   5527
Cards
Entrez_Gene (NCBI)IGHG3  3502  immunoglobulin heavy constant gamma 3 (G3m marker)
AliasesIgG3
GeneCards (Weizmann)IGHG3
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr14_KI270846v1_alt:236872-852000 [Contig_View]  IGHG3 [Vega]
TCGA cBioPortalIGHG3
AceView (NCBI)IGHG3
Genatlas (Paris)IGHG3
WikiGenes3502
SOURCE (Princeton)IGHG3
Genetics Home Reference (NIH)IGHG3
Genomic and cartography
GoldenPath hg38 (UCSC)IGHG3  -     chr14_KI270846v1_alt:236872-852000 -  14_KI270846v1_alt   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IGHG3  -     14_KI270846v1_alt   [Description]    (hg19-Feb_2009)
EnsemblIGHG3 - 14_KI270846v1_alt [CytoView hg19]  IGHG3 - 14_KI270846v1_alt [CytoView hg38]
Mapping of homologs : NCBIIGHG3 [Mapview hg19]  IGHG3 [Mapview hg38]
OMIM147120   
Gene and transcription
Genbank (Entrez)AK097307 AK097355 AK097572 AK097906 AK098108
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)NC_000014 NG_001019 NT_187600
Consensus coding sequences : CCDS (NCBI)IGHG3
Cluster EST : UnigeneHs.510635 [ NCBI ]
CGAP (NCI)Hs.510635
Gene ExpressionIGHG3 [ NCBI-GEO ]   IGHG3 [ EBI - ARRAY_EXPRESS ]   IGHG3 [ SEEK ]   IGHG3 [ MEM ]
Gene Expression Viewer (FireBrowse)IGHG3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3502
GTEX Portal (Tissue expression)IGHG3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01860   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01860  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01860
Splice isoforms : SwissVarP01860
PhosPhoSitePlusP01860
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_C1-set   
Domain families : Pfam (Sanger)C1-set (PF07654)   
Domain families : Pfam (NCBI)pfam07654   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)IGHG3
DMDM Disease mutations3502
Blocks (Seattle)IGHG3
PDB (SRS)4WWI    4ZNC   
PDB (PDBSum)4WWI    4ZNC   
PDB (IMB)4WWI    4ZNC   
PDB (RSDB)4WWI    4ZNC   
Structural Biology KnowledgeBase4WWI    4ZNC   
SCOP (Structural Classification of Proteins)4WWI    4ZNC   
CATH (Classification of proteins structures)4WWI    4ZNC   
SuperfamilyP01860
Peptide AtlasP01860
IPIIPI00973474   
Protein Interaction databases
DIP (DOE-UCLA)P01860
IntAct (EBI)P01860
BioGRIDIGHG3
STRING (EMBL)IGHG3
ZODIACIGHG3
Ontologies - Pathways
QuickGOP01860
Ontology : AmiGOretina homeostasis  antigen binding  serine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  phagocytosis, recognition  phagocytosis, engulfment  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  extracellular exosome  blood microparticle  
Ontology : EGO-EBIretina homeostasis  antigen binding  serine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  phagocytosis, recognition  phagocytosis, engulfment  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  extracellular exosome  blood microparticle  
NDEx NetworkIGHG3
Atlas of Cancer Signalling NetworkIGHG3
Wikipedia pathwaysIGHG3
Orthology - Evolution
OrthoDB3502
Phylogenetic Trees/Animal Genes : TreeFamIGHG3
HOVERGENP01860
HOGENOMP01860
Homologs : HomoloGeneIGHG3
Homology/Alignments : Family Browser (UCSC)IGHG3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIGHG3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IGHG3
dbVarIGHG3
ClinVarIGHG3
1000_GenomesIGHG3 
Exome Variant ServerIGHG3
ExAC (Exome Aggregation Consortium)IGHG3 (select the gene name)
Genetic variants : HAPMAP3502
Genomic Variants (DGV)IGHG3 [DGVbeta]
DECIPHERIGHG3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIGHG3 
Mutations
ICGC Data PortalIGHG3 
TCGA Data PortalIGHG3 
Broad Tumor PortalIGHG3
OASIS PortalIGHG3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIGHG3
BioMutasearch IGHG3
DgiDB (Drug Gene Interaction Database)IGHG3
DoCM (Curated mutations)IGHG3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IGHG3 (select a term)
intoGenIGHG3
Cancer3DIGHG3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147120   
Orphanet
MedgenIGHG3
Genetic Testing Registry IGHG3
NextProtP01860 [Medical]
TSGene3502
GENETestsIGHG3
Target ValidationIGHG3
Huge Navigator IGHG3 [HugePedia]
snp3D : Map Gene to Disease3502
BioCentury BCIQIGHG3
ClinGenIGHG3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3502
Chemical/Pharm GKB GenePA29718
Clinical trialIGHG3
Miscellaneous
canSAR (ICR)IGHG3 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIGHG3
EVEXIGHG3
GoPubMedIGHG3
iHOPIGHG3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:12:58 CEST 2017

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