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IGHG4 (immunoglobulin heavy constant gamma 4 (G4m marker))

Identity

Other alias-
HGNC (Hugo) IGHG4
LocusID (NCBI) 3503
Atlas_Id 64550
Location 14_KI270846v1_alt  [Link to chromosome band 14]
Location_base_pair Starts at 136022 and ends at 136336 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IGKC (2p11.2) / IGHG4 (14q32.33)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)IGHG4   5528
Cards
Entrez_Gene (NCBI)IGHG4  3503  immunoglobulin heavy constant gamma 4 (G4m marker)
Aliases
GeneCards (Weizmann)IGHG4
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr14_KI270846v1_alt:136022-136336 [Contig_View]  IGHG4 [Vega]
TCGA cBioPortalIGHG4
AceView (NCBI)IGHG4
Genatlas (Paris)IGHG4
WikiGenes3503
SOURCE (Princeton)IGHG4
Genetics Home Reference (NIH)IGHG4
Genomic and cartography
GoldenPath hg38 (UCSC)IGHG4  -     chr14_KI270846v1_alt:136022-136336 -  14_KI270846v1_alt   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IGHG4  -     14_KI270846v1_alt   [Description]    (hg19-Feb_2009)
EnsemblIGHG4 - 14_KI270846v1_alt [CytoView hg19]  IGHG4 - 14_KI270846v1_alt [CytoView hg38]
Mapping of homologs : NCBIIGHG4 [Mapview hg19]  IGHG4 [Mapview hg38]
OMIM147130   
Gene and transcription
Genbank (Entrez)AJ294733 BC025985 BC111019 BX640824
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_001019 NT_187600
Consensus coding sequences : CCDS (NCBI)IGHG4
Cluster EST : UnigeneHs.510635 [ NCBI ]
CGAP (NCI)Hs.510635
Gene ExpressionIGHG4 [ NCBI-GEO ]   IGHG4 [ EBI - ARRAY_EXPRESS ]   IGHG4 [ SEEK ]   IGHG4 [ MEM ]
Gene Expression Viewer (FireBrowse)IGHG4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3503
GTEX Portal (Tissue expression)IGHG4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01861   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01861  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01861
Splice isoforms : SwissVarP01861
PhosPhoSitePlusP01861
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_C1-set   
Domain families : Pfam (Sanger)C1-set (PF07654)   
Domain families : Pfam (NCBI)pfam07654   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)IGHG4
DMDM Disease mutations3503
Blocks (Seattle)IGHG4
PDB (SRS)1ADQ    1BBJ    2FL5    4B53    4C54    4C55    4D2N    5LG1   
PDB (PDBSum)1ADQ    1BBJ    2FL5    4B53    4C54    4C55    4D2N    5LG1   
PDB (IMB)1ADQ    1BBJ    2FL5    4B53    4C54    4C55    4D2N    5LG1   
PDB (RSDB)1ADQ    1BBJ    2FL5    4B53    4C54    4C55    4D2N    5LG1   
Structural Biology KnowledgeBase1ADQ    1BBJ    2FL5    4B53    4C54    4C55    4D2N    5LG1   
SCOP (Structural Classification of Proteins)1ADQ    1BBJ    2FL5    4B53    4C54    4C55    4D2N    5LG1   
CATH (Classification of proteins structures)1ADQ    1BBJ    2FL5    4B53    4C54    4C55    4D2N    5LG1   
SuperfamilyP01861
Peptide AtlasP01861
IPIIPI00930442   
Protein Interaction databases
DIP (DOE-UCLA)P01861
IntAct (EBI)P01861
BioGRIDIGHG4
STRING (EMBL)IGHG4
ZODIACIGHG4
Ontologies - Pathways
QuickGOP01861
Ontology : AmiGOantigen binding  serine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  phagocytosis, recognition  phagocytosis, engulfment  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  extracellular exosome  blood microparticle  
Ontology : EGO-EBIantigen binding  serine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  phagocytosis, recognition  phagocytosis, engulfment  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  extracellular exosome  blood microparticle  
NDEx NetworkIGHG4
Atlas of Cancer Signalling NetworkIGHG4
Wikipedia pathwaysIGHG4
Orthology - Evolution
OrthoDB3503
Phylogenetic Trees/Animal Genes : TreeFamIGHG4
HOVERGENP01861
HOGENOMP01861
Homologs : HomoloGeneIGHG4
Homology/Alignments : Family Browser (UCSC)IGHG4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIGHG4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IGHG4
dbVarIGHG4
ClinVarIGHG4
1000_GenomesIGHG4 
Exome Variant ServerIGHG4
ExAC (Exome Aggregation Consortium)IGHG4 (select the gene name)
Genetic variants : HAPMAP3503
Genomic Variants (DGV)IGHG4 [DGVbeta]
DECIPHERIGHG4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIGHG4 
Mutations
ICGC Data PortalIGHG4 
TCGA Data PortalIGHG4 
Broad Tumor PortalIGHG4
OASIS PortalIGHG4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIGHG4
BioMutasearch IGHG4
DgiDB (Drug Gene Interaction Database)IGHG4
DoCM (Curated mutations)IGHG4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IGHG4 (select a term)
intoGenIGHG4
Cancer3DIGHG4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147130   
Orphanet
MedgenIGHG4
Genetic Testing Registry IGHG4
NextProtP01861 [Medical]
TSGene3503
GENETestsIGHG4
Target ValidationIGHG4
Huge Navigator IGHG4 [HugePedia]
snp3D : Map Gene to Disease3503
BioCentury BCIQIGHG4
ClinGenIGHG4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3503
Chemical/Pharm GKB GenePA29719
Clinical trialIGHG4
Miscellaneous
canSAR (ICR)IGHG4 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIGHG4
EVEXIGHG4
GoPubMedIGHG4
iHOPIGHG4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:53:13 CEST 2017

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