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IGHM (immunoglobulin heavy constant mu)

Identity

Other aliasAGM1
MU
VH
HGNC (Hugo) IGHM
LocusID (NCBI) 3507
Atlas_Id 45610
Location 14q32.33  [Link to chromosome band 14q32]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)IGHM   5541
Cards
Entrez_Gene (NCBI)IGHM  3507  immunoglobulin heavy constant mu
AliasesAGM1; MU; VH
GeneCards (Weizmann)IGHM
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  - [Contig_View]  IGHM [Vega]
TCGA cBioPortalIGHM
AceView (NCBI)IGHM
Genatlas (Paris)IGHM
WikiGenes3507
SOURCE (Princeton)IGHM
Genetics Home Reference (NIH)IGHM
Genomic and cartography
GoldenPath hg38 (UCSC)IGHM  -  
GoldenPath hg19 (UCSC)IGHM  -  
EnsemblIGHM - [CytoView hg19]  IGHM - [CytoView hg38]
Mapping of homologs : NCBIIGHM [Mapview hg19]  IGHM [Mapview hg38]
OMIM147020   601495   
Gene and transcription
Genbank (Entrez)AH002768 AK090464 AK092976 AK097859 AK097950
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)NC_000014 NG_001019 NT_187600
Consensus coding sequences : CCDS (NCBI)IGHM
Cluster EST : UnigeneHs.510635 [ NCBI ]
CGAP (NCI)Hs.510635
Gene ExpressionIGHM [ NCBI-GEO ]   IGHM [ EBI - ARRAY_EXPRESS ]   IGHM [ SEEK ]   IGHM [ MEM ]
Gene Expression Viewer (FireBrowse)IGHM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3507
GTEX Portal (Tissue expression)IGHM
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01871   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01871  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01871
Splice isoforms : SwissVarP01871
PhosPhoSitePlusP01871
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig/MHC_CS    Ig_C1-set   
Domain families : Pfam (Sanger)C1-set (PF07654)   
Domain families : Pfam (NCBI)pfam07654   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)IGHM
DMDM Disease mutations3507
Blocks (Seattle)IGHM
PDB (SRS)1HEZ    2AGJ   
PDB (PDBSum)1HEZ    2AGJ   
PDB (IMB)1HEZ    2AGJ   
PDB (RSDB)1HEZ    2AGJ   
Structural Biology KnowledgeBase1HEZ    2AGJ   
SCOP (Structural Classification of Proteins)1HEZ    2AGJ   
CATH (Classification of proteins structures)1HEZ    2AGJ   
SuperfamilyP01871
Peptide AtlasP01871
IPIIPI00896380   IPI00418153   IPI00479708   IPI00973588   IPI00168728   IPI00973513   
Protein Interaction databases
DIP (DOE-UCLA)P01871
IntAct (EBI)P01871
BioGRIDIGHM
STRING (EMBL)IGHM
ZODIACIGHM
Ontologies - Pathways
QuickGOP01871
Ontology : AmiGOadaptive immune response  single-stranded DNA binding  antigen binding  antigen binding  protein binding  extracellular space  extracellular space  plasma membrane  phagocytosis, recognition  phagocytosis, engulfment  complement activation, classical pathway  external side of plasma membrane  cell surface  integral component of membrane  antibacterial humoral response  phosphatidylcholine binding  immunoglobulin receptor binding  immunoglobulin receptor binding  immunoglobulin complex, circulating  defense response to bacterium  peptidoglycan binding  innate immune response  innate immune response  defense response to Gram-negative bacterium  B cell receptor signaling pathway  positive regulation of B cell activation  leukocyte migration  extracellular exosome  pentameric IgM immunoglobulin complex  hexameric IgM immunoglobulin complex  blood microparticle  
Ontology : EGO-EBIadaptive immune response  single-stranded DNA binding  antigen binding  antigen binding  protein binding  extracellular space  extracellular space  plasma membrane  phagocytosis, recognition  phagocytosis, engulfment  complement activation, classical pathway  external side of plasma membrane  cell surface  integral component of membrane  antibacterial humoral response  phosphatidylcholine binding  immunoglobulin receptor binding  immunoglobulin receptor binding  immunoglobulin complex, circulating  defense response to bacterium  peptidoglycan binding  innate immune response  innate immune response  defense response to Gram-negative bacterium  B cell receptor signaling pathway  positive regulation of B cell activation  leukocyte migration  extracellular exosome  pentameric IgM immunoglobulin complex  hexameric IgM immunoglobulin complex  blood microparticle  
NDEx NetworkIGHM
Atlas of Cancer Signalling NetworkIGHM
Wikipedia pathwaysIGHM
Orthology - Evolution
OrthoDB3507
Phylogenetic Trees/Animal Genes : TreeFamIGHM
HOVERGENP01871
HOGENOMP01871
Homologs : HomoloGeneIGHM
Homology/Alignments : Family Browser (UCSC)IGHM
Gene fusions - Rearrangements
Fusion : QuiverIGHM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIGHM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IGHM
dbVarIGHM
ClinVarIGHM
1000_GenomesIGHM 
Exome Variant ServerIGHM
Varsome BrowserIGHM
Genetic variants : HAPMAP3507
Genomic Variants (DGV)IGHM [DGVbeta]
DECIPHERIGHM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIGHM 
Mutations
ICGC Data PortalIGHM 
TCGA Data PortalIGHM 
Broad Tumor PortalIGHM
OASIS PortalIGHM [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIGHM
BioMutasearch IGHM
DgiDB (Drug Gene Interaction Database)IGHM
DoCM (Curated mutations)IGHM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IGHM (select a term)
intoGenIGHM
Cancer3DIGHM(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147020    601495   
Orphanet10310   
DisGeNETIGHM
MedgenIGHM
Genetic Testing Registry IGHM
NextProtP01871 [Medical]
TSGene3507
GENETestsIGHM
Target ValidationIGHM
Huge Navigator IGHM [HugePedia]
snp3D : Map Gene to Disease3507
BioCentury BCIQIGHM
ClinGenIGHM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3507
Chemical/Pharm GKB GenePA29730
Clinical trialIGHM
Miscellaneous
canSAR (ICR)IGHM (select the gene name)
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIGHM
EVEXIGHM
GoPubMedIGHM
iHOPIGHM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Aug 16 11:07:52 CEST 2018

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