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IGHV3-21 (immunoglobulin heavy variable 3-21)

Identity

Other aliasIGHV321
VH
HGNC (Hugo) IGHV3-21
LocusID (NCBI) 28444
Atlas_Id 43713
Location 14q32.33  [Link to chromosome band 14q32]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)IGHV3-21   5586
Cards
Entrez_Gene (NCBI)IGHV3-21  28444  immunoglobulin heavy variable 3-21
AliasesIGHV321; VH
GeneCards (Weizmann)IGHV3-21
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  - [Contig_View]  IGHV3-21 [Vega]
TCGA cBioPortalIGHV3-21
AceView (NCBI)IGHV3-21
Genatlas (Paris)IGHV3-21
WikiGenes28444
SOURCE (Princeton)IGHV3-21
Genetics Home Reference (NIH)IGHV3-21
Genomic and cartography
GoldenPath hg38 (UCSC)IGHV3-21  -  
GoldenPath hg19 (UCSC)IGHV3-21  -  
EnsemblIGHV3-21 - [CytoView hg19]  IGHV3-21 - [CytoView hg38]
Mapping of homologs : NCBIIGHV3-21 [Mapview hg19]  IGHV3-21 [Mapview hg38]
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_001019 NT_187600
Consensus coding sequences : CCDS (NCBI)IGHV3-21
Gene ExpressionIGHV3-21 [ NCBI-GEO ]   IGHV3-21 [ EBI - ARRAY_EXPRESS ]   IGHV3-21 [ SEEK ]   IGHV3-21 [ MEM ]
Gene Expression Viewer (FireBrowse)IGHV3-21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28444
GTEX Portal (Tissue expression)IGHV3-21
Protein : pattern, domain, 3D structure
UniProt/SwissProtA0A0B4J1V1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA0A0B4J1V1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA0A0B4J1V1
Splice isoforms : SwissVarA0A0B4J1V1
PhosPhoSitePlusA0A0B4J1V1
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IGv (SM00406)  
Conserved Domain (NCBI)IGHV3-21
DMDM Disease mutations28444
Blocks (Seattle)IGHV3-21
SuperfamilyA0A0B4J1V1
Peptide AtlasA0A0B4J1V1
Protein Interaction databases
DIP (DOE-UCLA)A0A0B4J1V1
IntAct (EBI)A0A0B4J1V1
BioGRIDIGHV3-21
STRING (EMBL)IGHV3-21
ZODIACIGHV3-21
Ontologies - Pathways
QuickGOA0A0B4J1V1
Ontology : AmiGOantigen binding  phagocytosis, recognition  phagocytosis, engulfment  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  blood microparticle  
Ontology : EGO-EBIantigen binding  phagocytosis, recognition  phagocytosis, engulfment  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  blood microparticle  
NDEx NetworkIGHV3-21
Atlas of Cancer Signalling NetworkIGHV3-21
Wikipedia pathwaysIGHV3-21
Orthology - Evolution
OrthoDB28444
Phylogenetic Trees/Animal Genes : TreeFamIGHV3-21
HOVERGENA0A0B4J1V1
HOGENOMA0A0B4J1V1
Homologs : HomoloGeneIGHV3-21
Homology/Alignments : Family Browser (UCSC)IGHV3-21
Gene fusions - Rearrangements
Tumor Fusion PortalIGHV3-21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIGHV3-21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IGHV3-21
dbVarIGHV3-21
ClinVarIGHV3-21
1000_GenomesIGHV3-21 
Exome Variant ServerIGHV3-21
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP28444
Genomic Variants (DGV)IGHV3-21 [DGVbeta]
DECIPHERIGHV3-21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIGHV3-21 
Mutations
ICGC Data PortalIGHV3-21 
TCGA Data PortalIGHV3-21 
Broad Tumor PortalIGHV3-21
OASIS PortalIGHV3-21 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIGHV3-21
BioMutasearch IGHV3-21
DgiDB (Drug Gene Interaction Database)IGHV3-21
DoCM (Curated mutations)IGHV3-21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IGHV3-21 (select a term)
intoGenIGHV3-21
Cancer3DIGHV3-21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet10899   
DisGeNETIGHV3-21
MedgenIGHV3-21
Genetic Testing Registry IGHV3-21
NextProtA0A0B4J1V1 [Medical]
TSGene28444
GENETestsIGHV3-21
Target ValidationIGHV3-21
Huge Navigator IGHV3-21 [HugePedia]
snp3D : Map Gene to Disease28444
BioCentury BCIQIGHV3-21
ClinGenIGHV3-21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD28444
Chemical/Pharm GKB GenePA35186
Clinical trialIGHV3-21
Miscellaneous
canSAR (ICR)IGHV3-21 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIGHV3-21
EVEXIGHV3-21
GoPubMedIGHV3-21
iHOPIGHV3-21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:17:30 CET 2017

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