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IGLC1 (immunoglobulin lambda constant 1)

Identity

Alias_namesIGLC
immunoglobulin lambda constant 1 (Mcg marker)
Other alias
HGNC (Hugo) IGLC1
LocusID (NCBI) 3537
Atlas_Id 64565
Location 22q11.22  [Link to chromosome band 22q11]
Location_base_pair Starts at 22712404 and ends at 22896105 bp from pter ( according to hg38-Dec_2013)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)IGLC1   5855
Cards
Entrez_Gene (NCBI)IGLC1  3537  immunoglobulin lambda constant 1
AliasesIGLC
GeneCards (Weizmann)IGLC1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr22:22712404-22896105 [Contig_View]  IGLC1 [Vega]
TCGA cBioPortalIGLC1
AceView (NCBI)IGLC1
Genatlas (Paris)IGLC1
WikiGenes3537
SOURCE (Princeton)IGLC1
Genetics Home Reference (NIH)IGLC1
Genomic and cartography
GoldenPath hg38 (UCSC)IGLC1  -     chr22:22712404-22896105 +  22q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IGLC1  -     22q11.22   [Description]    (hg19-Feb_2009)
EnsemblIGLC1 - 22q11.22 [CytoView hg19]  IGLC1 - 22q11.22 [CytoView hg38]
Mapping of homologs : NCBIIGLC1 [Mapview hg19]  IGLC1 [Mapview hg38]
OMIM147220   
Gene and transcription
Genbank (Entrez)BC007782 BC012159
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IGLC1
Cluster EST : UnigeneHs.449585 [ NCBI ]
CGAP (NCI)Hs.449585
Gene ExpressionIGLC1 [ NCBI-GEO ]   IGLC1 [ EBI - ARRAY_EXPRESS ]   IGLC1 [ SEEK ]   IGLC1 [ MEM ]
Gene Expression Viewer (FireBrowse)IGLC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3537
GTEX Portal (Tissue expression)IGLC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0CG04   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0CG04  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0CG04
Splice isoforms : SwissVarP0CG04
PhosPhoSitePlusP0CG04
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_C1-set   
Domain families : Pfam (Sanger)C1-set (PF07654)   
Domain families : Pfam (NCBI)pfam07654   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)IGLC1
DMDM Disease mutations3537
Blocks (Seattle)IGLC1
PDB (SRS)1ZVO    2FB4    2IG2   
PDB (PDBSum)1ZVO    2FB4    2IG2   
PDB (IMB)1ZVO    2FB4    2IG2   
PDB (RSDB)1ZVO    2FB4    2IG2   
Structural Biology KnowledgeBase1ZVO    2FB4    2IG2   
SCOP (Structural Classification of Proteins)1ZVO    2FB4    2IG2   
CATH (Classification of proteins structures)1ZVO    2FB4    2IG2   
SuperfamilyP0CG04
Peptide AtlasP0CG04
IPIIPI00852577   IPI00973428   IPI00719373   IPI00973424   
Protein Interaction databases
DIP (DOE-UCLA)P0CG04
IntAct (EBI)P0CG04
BioGRIDIGLC1
STRING (EMBL)IGLC1
ZODIACIGLC1
Ontologies - Pathways
QuickGOP0CG04
Ontology : AmiGOantigen binding  antigen binding  serine-type endopeptidase activity  extracellular region  extracellular space  plasma membrane  proteolysis  receptor-mediated endocytosis  phagocytosis, recognition  phagocytosis, engulfment  immune response  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-epsilon receptor signaling pathway  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  regulation of immune response  B cell receptor signaling pathway  positive regulation of B cell activation  leukocyte migration  extracellular exosome  blood microparticle  
Ontology : EGO-EBIantigen binding  antigen binding  serine-type endopeptidase activity  extracellular region  extracellular space  plasma membrane  proteolysis  receptor-mediated endocytosis  phagocytosis, recognition  phagocytosis, engulfment  immune response  complement activation  complement activation, classical pathway  complement activation, classical pathway  external side of plasma membrane  immunoglobulin receptor binding  Fc-epsilon receptor signaling pathway  Fc-gamma receptor signaling pathway involved in phagocytosis  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  regulation of immune response  B cell receptor signaling pathway  positive regulation of B cell activation  leukocyte migration  extracellular exosome  blood microparticle  
NDEx NetworkIGLC1
Atlas of Cancer Signalling NetworkIGLC1
Wikipedia pathwaysIGLC1
Orthology - Evolution
OrthoDB3537
Phylogenetic Trees/Animal Genes : TreeFamIGLC1
HOVERGENP0CG04
HOGENOMP0CG04
Homologs : HomoloGeneIGLC1
Homology/Alignments : Family Browser (UCSC)IGLC1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIGLC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IGLC1
dbVarIGLC1
ClinVarIGLC1
1000_GenomesIGLC1 
Exome Variant ServerIGLC1
ExAC (Exome Aggregation Consortium)IGLC1 (select the gene name)
Genetic variants : HAPMAP3537
Genomic Variants (DGV)IGLC1 [DGVbeta]
DECIPHERIGLC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIGLC1 
Mutations
ICGC Data PortalIGLC1 
TCGA Data PortalIGLC1 
Broad Tumor PortalIGLC1
OASIS PortalIGLC1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIGLC1
BioMutasearch IGLC1
DgiDB (Drug Gene Interaction Database)IGLC1
DoCM (Curated mutations)IGLC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IGLC1 (select a term)
intoGenIGLC1
Cancer3DIGLC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147220   
Orphanet
MedgenIGLC1
Genetic Testing Registry IGLC1
NextProtP0CG04 [Medical]
TSGene3537
GENETestsIGLC1
Target ValidationIGLC1
Huge Navigator IGLC1 [HugePedia]
snp3D : Map Gene to Disease3537
BioCentury BCIQIGLC1
ClinGenIGLC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3537
Chemical/Pharm GKB GenePA29742
Clinical trialIGLC1
Miscellaneous
canSAR (ICR)IGLC1 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIGLC1
EVEXIGLC1
GoPubMedIGLC1
iHOPIGLC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:11:06 CEST 2017

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