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IGLL1 (immunoglobulin lambda like polypeptide 1)

Identity

Alias_namesIGLL
immunoglobulin lambda-like polypeptide 1
Alias_symbol (synonym)IGVPB
IGL5
14.1
CD179B
Other aliasAGM2
CD179b
IGL1
IGLJ14.1
IGO
VPREB2
HGNC (Hugo) IGLL1
LocusID (NCBI) 3543
Atlas_Id 64567
Location 22q11.23  [Link to chromosome band 22q11]
Location_base_pair Starts at 23573126 and ends at 23580308 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CCND1 (11q13.3) / IGLL1 (22q11.23)SNAP29 (22q11.21) / IGLL1 (22q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IGLL1   5870
LRG (Locus Reference Genomic)LRG_69
Cards
Entrez_Gene (NCBI)IGLL1  3543  immunoglobulin lambda like polypeptide 1
Aliases14.1; AGM2; CD179b; IGL1; 
IGL5; IGLJ14.1; IGLL; IGO; IGVPB; VPREB2
GeneCards (Weizmann)IGLL1
Ensembl hg19 (Hinxton)ENSG00000128322 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128322 [Gene_View]  chr22:23573126-23580308 [Contig_View]  IGLL1 [Vega]
ICGC DataPortalENSG00000128322
TCGA cBioPortalIGLL1
AceView (NCBI)IGLL1
Genatlas (Paris)IGLL1
WikiGenes3543
SOURCE (Princeton)IGLL1
Genetics Home Reference (NIH)IGLL1
Genomic and cartography
GoldenPath hg38 (UCSC)IGLL1  -     chr22:23573126-23580308 -  22q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IGLL1  -     22q11.23   [Description]    (hg19-Feb_2009)
EnsemblIGLL1 - 22q11.23 [CytoView hg19]  IGLL1 - 22q11.23 [CytoView hg38]
Mapping of homologs : NCBIIGLL1 [Mapview hg19]  IGLL1 [Mapview hg38]
OMIM146770   613500   
Gene and transcription
Genbank (Entrez)BC012293 BC030239 DQ893578 DQ894640 M27749
RefSeq transcript (Entrez)NM_020070 NM_152855
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IGLL1
Cluster EST : UnigeneHs.348935 [ NCBI ]
CGAP (NCI)Hs.348935
Alternative Splicing GalleryENSG00000128322
Gene ExpressionIGLL1 [ NCBI-GEO ]   IGLL1 [ EBI - ARRAY_EXPRESS ]   IGLL1 [ SEEK ]   IGLL1 [ MEM ]
Gene Expression Viewer (FireBrowse)IGLL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3543
GTEX Portal (Tissue expression)IGLL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15814   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15814  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15814
Splice isoforms : SwissVarP15814
PhosPhoSitePlusP15814
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_C1-set   
Domain families : Pfam (Sanger)C1-set (PF07654)   
Domain families : Pfam (NCBI)pfam07654   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)IGLL1
DMDM Disease mutations3543
Blocks (Seattle)IGLL1
PDB (SRS)2H32    2H3N    2LKQ   
PDB (PDBSum)2H32    2H3N    2LKQ   
PDB (IMB)2H32    2H3N    2LKQ   
PDB (RSDB)2H32    2H3N    2LKQ   
Structural Biology KnowledgeBase2H32    2H3N    2LKQ   
SCOP (Structural Classification of Proteins)2H32    2H3N    2LKQ   
CATH (Classification of proteins structures)2H32    2H3N    2LKQ   
SuperfamilyP15814
Human Protein AtlasENSG00000128322
Peptide AtlasP15814
HPRD00905
IPIIPI00013438   IPI00954259   IPI00333335   IPI00880175   
Protein Interaction databases
DIP (DOE-UCLA)P15814
IntAct (EBI)P15814
FunCoupENSG00000128322
BioGRIDIGLL1
STRING (EMBL)IGLL1
ZODIACIGLL1
Ontologies - Pathways
QuickGOP15814
Ontology : AmiGOantigen binding  extracellular region  phagocytosis, recognition  phagocytosis, engulfment  immune response  complement activation, classical pathway  external side of plasma membrane  membrane  immunoglobulin receptor binding  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  leukocyte migration  extracellular exosome  blood microparticle  
Ontology : EGO-EBIantigen binding  extracellular region  phagocytosis, recognition  phagocytosis, engulfment  immune response  complement activation, classical pathway  external side of plasma membrane  membrane  immunoglobulin receptor binding  immunoglobulin complex, circulating  defense response to bacterium  innate immune response  B cell receptor signaling pathway  positive regulation of B cell activation  leukocyte migration  extracellular exosome  blood microparticle  
Pathways : KEGGPrimary immunodeficiency   
NDEx NetworkIGLL1
Atlas of Cancer Signalling NetworkIGLL1
Wikipedia pathwaysIGLL1
Orthology - Evolution
OrthoDB3543
GeneTree (enSembl)ENSG00000128322
Phylogenetic Trees/Animal Genes : TreeFamIGLL1
HOVERGENP15814
HOGENOMP15814
Homologs : HomoloGeneIGLL1
Homology/Alignments : Family Browser (UCSC)IGLL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIGLL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IGLL1
dbVarIGLL1
ClinVarIGLL1
1000_GenomesIGLL1 
Exome Variant ServerIGLL1
ExAC (Exome Aggregation Consortium)IGLL1 (select the gene name)
Genetic variants : HAPMAP3543
Genomic Variants (DGV)IGLL1 [DGVbeta]
DECIPHERIGLL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIGLL1 
Mutations
ICGC Data PortalIGLL1 
TCGA Data PortalIGLL1 
Broad Tumor PortalIGLL1
OASIS PortalIGLL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIGLL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIGLL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch IGLL1
DgiDB (Drug Gene Interaction Database)IGLL1
DoCM (Curated mutations)IGLL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IGLL1 (select a term)
intoGenIGLL1
Cancer3DIGLL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM146770    613500   
Orphanet10310   
MedgenIGLL1
Genetic Testing Registry IGLL1
NextProtP15814 [Medical]
TSGene3543
GENETestsIGLL1
Target ValidationIGLL1
Huge Navigator IGLL1 [HugePedia]
snp3D : Map Gene to Disease3543
BioCentury BCIQIGLL1
ClinGenIGLL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3543
Chemical/Pharm GKB GenePA29756
Clinical trialIGLL1
Miscellaneous
canSAR (ICR)IGLL1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIGLL1
EVEXIGLL1
GoPubMedIGLL1
iHOPIGLL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:11:06 CEST 2017

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