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IHH (indian hedgehog)

Identity

Alias_namesIndian hedgehog (Drosophila) homolog
Indian hedgehog homolog (Drosophila)
Alias_symbol (synonym)HHG2
BDA1
Other alias
HGNC (Hugo) IHH
LocusID (NCBI) 3549
Atlas_Id 43961
Location 2q35  [Link to chromosome band 2q35]
Location_base_pair Starts at 219054420 and ends at 219060516 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IHH   5956
Cards
Entrez_Gene (NCBI)IHH  3549  indian hedgehog
AliasesBDA1; HHG2
GeneCards (Weizmann)IHH
Ensembl hg19 (Hinxton)ENSG00000163501 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163501 [Gene_View]  chr2:219054420-219060516 [Contig_View]  IHH [Vega]
ICGC DataPortalENSG00000163501
TCGA cBioPortalIHH
AceView (NCBI)IHH
Genatlas (Paris)IHH
WikiGenes3549
SOURCE (Princeton)IHH
Genetics Home Reference (NIH)IHH
Genomic and cartography
GoldenPath hg38 (UCSC)IHH  -     chr2:219054420-219060516 -  2q35   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IHH  -     2q35   [Description]    (hg19-Feb_2009)
EnsemblIHH - 2q35 [CytoView hg19]  IHH - 2q35 [CytoView hg38]
Mapping of homologs : NCBIIHH [Mapview hg19]  IHH [Mapview hg38]
OMIM112500   600726   607778   
Gene and transcription
Genbank (Entrez)AI802733 BC034757 BC136587 BC136588 L38517
RefSeq transcript (Entrez)NM_002181
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IHH
Cluster EST : UnigeneHs.654504 [ NCBI ]
CGAP (NCI)Hs.654504
Alternative Splicing GalleryENSG00000163501
Gene ExpressionIHH [ NCBI-GEO ]   IHH [ EBI - ARRAY_EXPRESS ]   IHH [ SEEK ]   IHH [ MEM ]
Gene Expression Viewer (FireBrowse)IHH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3549
GTEX Portal (Tissue expression)IHH
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14623   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14623  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14623
Splice isoforms : SwissVarQ14623
PhosPhoSitePlusQ14623
Domaine pattern : Prosite (Expaxy)INTEIN_N_TER (PS50817)   
Domains : Interpro (EBI)Hedgehog    Hedgehog/Intein_dom    Hedgehog_sig/DD-Pept_Zn-bd_dom    Hedgehog_signalling_dom    Hint_dom    Hint_dom_C    Hint_dom_N    IHH    Intein_N   
Domain families : Pfam (Sanger)HH_signal (PF01085)    Hint (PF01079)   
Domain families : Pfam (NCBI)pfam01085    pfam01079   
Domain families : Smart (EMBL)HintC (SM00305)  HintN (SM00306)  
Conserved Domain (NCBI)IHH
DMDM Disease mutations3549
Blocks (Seattle)IHH
PDB (SRS)3K7G    3K7H    3K7I    3K7J    3N1F    3N1M    3N1O    3N1P   
PDB (PDBSum)3K7G    3K7H    3K7I    3K7J    3N1F    3N1M    3N1O    3N1P   
PDB (IMB)3K7G    3K7H    3K7I    3K7J    3N1F    3N1M    3N1O    3N1P   
PDB (RSDB)3K7G    3K7H    3K7I    3K7J    3N1F    3N1M    3N1O    3N1P   
Structural Biology KnowledgeBase3K7G    3K7H    3K7I    3K7J    3N1F    3N1M    3N1O    3N1P   
SCOP (Structural Classification of Proteins)3K7G    3K7H    3K7I    3K7J    3N1F    3N1M    3N1O    3N1P   
CATH (Classification of proteins structures)3K7G    3K7H    3K7I    3K7J    3N1F    3N1M    3N1O    3N1P   
SuperfamilyQ14623
Human Protein AtlasENSG00000163501
Peptide AtlasQ14623
HPRD02839
IPIIPI00032190   
Protein Interaction databases
DIP (DOE-UCLA)Q14623
IntAct (EBI)Q14623
FunCoupENSG00000163501
BioGRIDIHH
STRING (EMBL)IHH
ZODIACIHH
Ontologies - Pathways
QuickGOQ14623
Ontology : AmiGOskeletal system development  heart looping  patched binding  calcium ion binding  extracellular space  plasma membrane  smoothened signaling pathway  cell-cell signaling  peptidase activity  negative regulation of signal transduction  intein-mediated protein splicing  positive regulation of chondrocyte differentiation  response to estradiol  negative regulation of T cell differentiation in thymus  negative regulation of immature T cell proliferation in thymus  positive regulation of T cell differentiation in thymus  negative regulation of apoptotic process  positive regulation of smoothened signaling pathway  positive regulation of transcription from RNA polymerase II promoter  positive regulation of alpha-beta T cell differentiation  negative regulation of alpha-beta T cell differentiation  positive regulation of epithelial cell proliferation  maternal process involved in female pregnancy  somite development  
Ontology : EGO-EBIskeletal system development  heart looping  patched binding  calcium ion binding  extracellular space  plasma membrane  smoothened signaling pathway  cell-cell signaling  peptidase activity  negative regulation of signal transduction  intein-mediated protein splicing  positive regulation of chondrocyte differentiation  response to estradiol  negative regulation of T cell differentiation in thymus  negative regulation of immature T cell proliferation in thymus  positive regulation of T cell differentiation in thymus  negative regulation of apoptotic process  positive regulation of smoothened signaling pathway  positive regulation of transcription from RNA polymerase II promoter  positive regulation of alpha-beta T cell differentiation  negative regulation of alpha-beta T cell differentiation  positive regulation of epithelial cell proliferation  maternal process involved in female pregnancy  somite development  
Pathways : KEGGHedgehog signaling pathway   
NDEx NetworkIHH
Atlas of Cancer Signalling NetworkIHH
Wikipedia pathwaysIHH
Orthology - Evolution
OrthoDB3549
GeneTree (enSembl)ENSG00000163501
Phylogenetic Trees/Animal Genes : TreeFamIHH
HOVERGENQ14623
HOGENOMQ14623
Homologs : HomoloGeneIHH
Homology/Alignments : Family Browser (UCSC)IHH
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIHH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IHH
dbVarIHH
ClinVarIHH
1000_GenomesIHH 
Exome Variant ServerIHH
ExAC (Exome Aggregation Consortium)IHH (select the gene name)
Genetic variants : HAPMAP3549
Genomic Variants (DGV)IHH [DGVbeta]
DECIPHERIHH [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIHH 
Mutations
ICGC Data PortalIHH 
TCGA Data PortalIHH 
Broad Tumor PortalIHH
OASIS PortalIHH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIHH  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIHH
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IHH
DgiDB (Drug Gene Interaction Database)IHH
DoCM (Curated mutations)IHH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IHH (select a term)
intoGenIHH
Cancer3DIHH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM112500    600726    607778   
Orphanet10825    12311   
MedgenIHH
Genetic Testing Registry IHH
NextProtQ14623 [Medical]
TSGene3549
GENETestsIHH
Target ValidationIHH
Huge Navigator IHH [HugePedia]
snp3D : Map Gene to Disease3549
BioCentury BCIQIHH
ClinGenIHH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3549
Chemical/Pharm GKB GenePA29769
Clinical trialIHH
Miscellaneous
canSAR (ICR)IHH (select the gene name)
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIHH
EVEXIHH
GoPubMedIHH
iHOPIHH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:38:14 CEST 2017

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