Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IKBKG (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma)

Identity

Other namesAMCBX1
FIP-3
FIP3
Fip3p
IKK-gamma
IP
IP1
IP2
IPD2
NEMO
ZC2HC9
HGNC (Hugo) IKBKG
LocusID (NCBI) 8517
Location Xq28
Location_base_pair Starts at 153770459 and ends at 153793261 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IKBKG   5961
Cards
Entrez_Gene (NCBI)IKBKG  8517  inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
GeneCards (Weizmann)IKBKG
Ensembl (Hinxton)ENSG00000073009 [Gene_View]  chrX:153770459-153793261 [Contig_View]  IKBKG [Vega]
ICGC DataPortalENSG00000073009
cBioPortalIKBKG
AceView (NCBI)IKBKG
Genatlas (Paris)IKBKG
WikiGenes8517
SOURCE (Princeton)NM_001099856 NM_001099857 NM_001145255 NM_003639
Genomic and cartography
GoldenPath (UCSC)IKBKG  -  Xq28   chrX:153770459-153793261 +  Xq28   [Description]    (hg19-Feb_2009)
EnsemblIKBKG - Xq28 [CytoView]
Mapping of homologs : NCBIIKBKG [Mapview]
OMIM300248   300291   300301   300584   300636   300640   308300   
Gene and transcription
Genbank (Entrez)AF062089 AF074382 AF091453 AF261086 AK000593
RefSeq transcript (Entrez)NM_001099856 NM_001099857 NM_001145255 NM_003639
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_009896 NT_011681 NW_001842419 NW_004929448
Consensus coding sequences : CCDS (NCBI)IKBKG
Cluster EST : UnigeneHs.43505 [ NCBI ]
CGAP (NCI)Hs.43505
Alternative Splicing : Fast-db (Paris)GSHG0031927
Alternative Splicing GalleryENSG00000073009
Gene ExpressionIKBKG [ NCBI-GEO ]     IKBKG [ SEEK ]   IKBKG [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6K9 (Uniprot)
NextProtQ9Y6K9  [Medical]
With graphics : InterProQ9Y6K9
Splice isoforms : SwissVarQ9Y6K9 (Swissvar)
Domains : Interpro (EBI)NEMO_N [organisation]  
Related proteins : CluSTrQ9Y6K9
Domain families : Pfam (Sanger)NEMO (PF11577)   
Domain families : Pfam (NCBI)pfam11577   
DMDM Disease mutations8517
Blocks (Seattle)Q9Y6K9
PDB (SRS)2JVX    2JVY    3BRT    3BRV    3CL3    3FX0   
PDB (PDBSum)2JVX    2JVY    3BRT    3BRV    3CL3    3FX0   
PDB (IMB)2JVX    2JVY    3BRT    3BRV    3CL3    3FX0   
PDB (RSDB)2JVX    2JVY    3BRT    3BRV    3CL3    3FX0   
Human Protein AtlasENSG00000073009 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9Y6K9
HPRD02217
IPIIPI00002411   IPI00641117   IPI00641409   IPI00645990   IPI00644803   IPI00645282   IPI00852757   IPI00852832   IPI00852631   IPI00852720   IPI00927428   IPI01014787   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6K9
IntAct (EBI)Q9Y6K9
FunCoupENSG00000073009
BioGRIDIKBKG
InParanoidQ9Y6K9
Interologous Interaction database Q9Y6K9
IntegromeDBIKBKG
STRING (EMBL)IKBKG
Ontologies - Pathways
Ontology : AmiGOactivation of MAPK activity  B cell homeostasis  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  signal transducer activity  protein binding  intracellular  nucleus  cytoplasm  cytosol  transcription, DNA-templated  apoptotic process  inflammatory response  immune response  cellular response to DNA damage stimulus  I-kappaB kinase/NF-kappaB signaling  activation of NF-kappaB-inducing kinase activity  JNK cascade  IkappaB kinase complex  IkappaB kinase complex  IkappaB kinase complex  response to virus  viral process  protein domain specific binding  positive regulation of type I interferon production  toll-like receptor 2 signaling pathway  toll-like receptor 3 signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 5 signaling pathway  toll-like receptor 9 signaling pathway  toll-like receptor 10 signaling pathway  TRIF-dependent toll-like receptor signaling pathway  nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway  Fc-epsilon receptor signaling pathway  toll-like receptor TLR1:TLR2 signaling pathway  toll-like receptor TLR6:TLR2 signaling pathway  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  protein heterodimerization activity  T cell receptor signaling pathway  T cell receptor signaling pathway  positive regulation of NF-kappaB transcription factor activity  positive regulation of NF-kappaB transcription factor activity  stress-activated MAPK cascade  nucleotide-binding oligomerization domain containing signaling pathway  
Ontology : EGO-EBIactivation of MAPK activity  B cell homeostasis  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  signal transducer activity  protein binding  intracellular  nucleus  cytoplasm  cytosol  transcription, DNA-templated  apoptotic process  inflammatory response  immune response  cellular response to DNA damage stimulus  I-kappaB kinase/NF-kappaB signaling  activation of NF-kappaB-inducing kinase activity  JNK cascade  IkappaB kinase complex  IkappaB kinase complex  IkappaB kinase complex  response to virus  viral process  protein domain specific binding  positive regulation of type I interferon production  toll-like receptor 2 signaling pathway  toll-like receptor 3 signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 5 signaling pathway  toll-like receptor 9 signaling pathway  toll-like receptor 10 signaling pathway  TRIF-dependent toll-like receptor signaling pathway  nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway  Fc-epsilon receptor signaling pathway  toll-like receptor TLR1:TLR2 signaling pathway  toll-like receptor TLR6:TLR2 signaling pathway  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  protein heterodimerization activity  T cell receptor signaling pathway  T cell receptor signaling pathway  positive regulation of NF-kappaB transcription factor activity  positive regulation of NF-kappaB transcription factor activity  stress-activated MAPK cascade  nucleotide-binding oligomerization domain containing signaling pathway  
Pathways : BIOCARTATNFR2 Signaling Pathway [Genes]    Influence of Ras and Rho proteins on G1 to S Transition [Genes]    NF-kB Signaling Pathway [Genes]    TNF/Stress Related Signaling [Genes]    AKT Signaling Pathway [Genes]    CD40L Signaling Pathway [Genes]    Toll-Like Receptor Pathway [Genes]    Acetylation and Deacetylation of RelA in The Nucleus [Genes]   
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Chemokine signaling pathway    NF-kappa B signaling pathway    PI3K-Akt signaling pathway    Apoptosis    Osteoclast differentiation    Toll-like receptor signaling pathway    NOD-like receptor signaling pathway    RIG-I-like receptor signaling pathway    Cytosolic DNA-sensing pathway    T cell receptor signaling pathway    B cell receptor signaling pathway    TNF signaling pathway    Adipocytokine signaling pathway    Epithelial cell signaling in Helicobacter pylori infection    Shigellosis    Chagas disease (American trypanosomiasis)    Toxoplasmosis    Hepatitis C    Hepatitis B    HTLV-I infection    Herpes simplex infection    Epstein-Barr virus infection    Pathways in cancer    Viral carcinogenesis    Pancreatic cancer    Prostate cancer    Chronic myeloid leukemia    Acute myeloid leukemia    Small cell lung cancer    Primary immunodeficiency   
Protein Interaction DatabaseIKBKG
Wikipedia pathwaysIKBKG
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)IKBKG
snp3D : Map Gene to Disease8517
SNP (GeneSNP Utah)IKBKG
SNP : HGBaseIKBKG
Genetic variants : HAPMAPIKBKG
Exome VariantIKBKG
1000_GenomesIKBKG 
ICGC programENSG00000073009 
Somatic Mutations in Cancer : COSMICIKBKG 
CONAN: Copy Number AnalysisIKBKG 
Mutations and Diseases : HGMDIKBKG
Mutations and Diseases : intOGenIKBKG
Genomic VariantsIKBKG  IKBKG [DGVbeta]
dbVarIKBKG
ClinVarIKBKG
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM300248    300291    300301    300584    300636    300640    308300   
MedgenIKBKG
GENETestsIKBKG
Disease Genetic AssociationIKBKG
Huge Navigator IKBKG [HugePedia]  IKBKG [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneIKBKG
Homology/Alignments : Family Browser (UCSC)IKBKG
Phylogenetic Trees/Animal Genes : TreeFamIKBKG
Chemical/Protein Interactions : CTD8517
Chemical/Pharm GKB GenePA29777
Clinical trialIKBKG
Cancer Resource (Charite)ENSG00000073009
Other databases
Probes
Litterature
PubMed334 Pubmed reference(s) in Entrez
CoreMineIKBKG
iHOPIKBKG
OncoSearchIKBKG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:56:30 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.