Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IKZF5 (IKAROS family zinc finger 5)

Identity

Alias (NCBI)PEGASUS
THC7
ZNFN1A5
HGNC (Hugo) IKZF5
HGNC Alias symbPegasus
FLJ22973
HGNC Previous nameZNFN1A5
HGNC Previous namezinc finger protein, subfamily 1A, 5
 zinc finger protein, subfamily 1A, 5 (Pegasus)
 IKAROS family zinc finger 5 (Pegasus)
LocusID (NCBI) 64376
Atlas_Id 64586
Location 10q26.13  [Link to chromosome band 10q26]
Location_base_pair Starts at 122990807 and ends at 123008795 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IKZF5 (10q26.13) / ELN (7q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)IKZF5   14283
Cards
Entrez_Gene (NCBI)IKZF5    IKAROS family zinc finger 5
AliasesPEGASUS; THC7; ZNFN1A5
GeneCards (Weizmann)IKZF5
Ensembl hg19 (Hinxton)ENSG00000095574 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000095574 [Gene_View]  ENSG00000095574 [Sequence]  chr10:122990807-123008795 [Contig_View]  IKZF5 [Vega]
ICGC DataPortalENSG00000095574
TCGA cBioPortalIKZF5
AceView (NCBI)IKZF5
Genatlas (Paris)IKZF5
SOURCE (Princeton)IKZF5
Genetics Home Reference (NIH)IKZF5
Genomic and cartography
GoldenPath hg38 (UCSC)IKZF5  -     chr10:122990807-123008795 -  10q26.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IKZF5  -     10q26.13   [Description]    (hg19-Feb_2009)
GoldenPathIKZF5 - 10q26.13 [CytoView hg19]  IKZF5 - 10q26.13 [CytoView hg38]
ImmunoBaseENSG00000095574
Genome Data Viewer NCBIIKZF5 [Mapview hg19]  
OMIM606238   619130   
Gene and transcription
Genbank (Entrez)AF230808 AI560579 AK023288 AK026626 AK055507
RefSeq transcript (Entrez)NM_001271840 NM_001372123 NM_001372124 NM_001372125 NM_001372126 NM_001372127 NM_001372128 NM_001372129 NM_001372130 NM_001372131
Consensus coding sequences : CCDS (NCBI)IKZF5
Gene ExpressionIKZF5 [ NCBI-GEO ]   IKZF5 [ EBI - ARRAY_EXPRESS ]   IKZF5 [ SEEK ]   IKZF5 [ MEM ]
Gene Expression Viewer (FireBrowse)IKZF5 [ Firebrowse - Broad ]
GenevisibleExpression of IKZF5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64376
GTEX Portal (Tissue expression)IKZF5
Human Protein AtlasENSG00000095574-IKZF5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H5V7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H5V7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H5V7
PhosPhoSitePlusQ9H5V7
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)IKZF5
SuperfamilyQ9H5V7
AlphaFold pdb e-kbQ9H5V7   
Human Protein Atlas [tissue]ENSG00000095574-IKZF5 [tissue]
HPRD05873
Protein Interaction databases
DIP (DOE-UCLA)Q9H5V7
IntAct (EBI)Q9H5V7
BioGRIDIKZF5
STRING (EMBL)IKZF5
ZODIACIKZF5
Ontologies - Pathways
QuickGOQ9H5V7
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II transcription regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  regulation of transcription by RNA polymerase II  zinc ion binding  protein domain specific binding  protein-containing complex  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II transcription regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  regulation of transcription by RNA polymerase II  zinc ion binding  protein domain specific binding  protein-containing complex  
NDEx NetworkIKZF5
Atlas of Cancer Signalling NetworkIKZF5
Wikipedia pathwaysIKZF5
Orthology - Evolution
OrthoDB64376
GeneTree (enSembl)ENSG00000095574
Phylogenetic Trees/Animal Genes : TreeFamIKZF5
Homologs : HomoloGeneIKZF5
Homology/Alignments : Family Browser (UCSC)IKZF5
Gene fusions - Rearrangements
Fusion : QuiverIKZF5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIKZF5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IKZF5
dbVarIKZF5
ClinVarIKZF5
MonarchIKZF5
1000_GenomesIKZF5 
Exome Variant ServerIKZF5
GNOMAD BrowserENSG00000095574
Varsome BrowserIKZF5
ACMGIKZF5 variants
VarityQ9H5V7
Genomic Variants (DGV)IKZF5 [DGVbeta]
DECIPHERIKZF5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIKZF5 
Mutations
ICGC Data PortalIKZF5 
TCGA Data PortalIKZF5 
Broad Tumor PortalIKZF5
OASIS PortalIKZF5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIKZF5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIKZF5
Mutations and Diseases : HGMDIKZF5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaIKZF5
DgiDB (Drug Gene Interaction Database)IKZF5
DoCM (Curated mutations)IKZF5
CIViC (Clinical Interpretations of Variants in Cancer)IKZF5
Cancer3DIKZF5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606238    619130   
Orphanet
DisGeNETIKZF5
MedgenIKZF5
Genetic Testing Registry IKZF5
NextProtQ9H5V7 [Medical]
GENETestsIKZF5
Target ValidationIKZF5
Huge Navigator IKZF5 [HugePedia]
ClinGenIKZF5
Clinical trials, drugs, therapy
MyCancerGenomeIKZF5
Protein Interactions : CTDIKZF5
Pharm GKB GenePA162391969
PharosQ9H5V7
Clinical trialIKZF5
Miscellaneous
canSAR (ICR)IKZF5
HarmonizomeIKZF5
DataMed IndexIKZF5
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIKZF5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:53:40 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.