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IKZF5 (IKAROS family zinc finger 5)

Identity

Alias_namesZNFN1A5
zinc finger protein, subfamily 1A, 5
zinc finger protein, subfamily 1A, 5 (Pegasus)
IKAROS family zinc finger 5 (Pegasus)
Alias_symbol (synonym)Pegasus
FLJ22973
Other aliasPEGASUS
HGNC (Hugo) IKZF5
LocusID (NCBI) 64376
Atlas_Id 64586
Location 10q26.13  [Link to chromosome band 10q26]
Location_base_pair Starts at 122990806 and ends at 123008687 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IKZF5 (10q26.13) / ELN (7q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IKZF5   14283
Cards
Entrez_Gene (NCBI)IKZF5  64376  IKAROS family zinc finger 5
AliasesPEGASUS; ZNFN1A5
GeneCards (Weizmann)IKZF5
Ensembl hg19 (Hinxton)ENSG00000095574 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000095574 [Gene_View]  chr10:122990806-123008687 [Contig_View]  IKZF5 [Vega]
ICGC DataPortalENSG00000095574
TCGA cBioPortalIKZF5
AceView (NCBI)IKZF5
Genatlas (Paris)IKZF5
WikiGenes64376
SOURCE (Princeton)IKZF5
Genetics Home Reference (NIH)IKZF5
Genomic and cartography
GoldenPath hg38 (UCSC)IKZF5  -     chr10:122990806-123008687 -  10q26.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IKZF5  -     10q26.13   [Description]    (hg19-Feb_2009)
EnsemblIKZF5 - 10q26.13 [CytoView hg19]  IKZF5 - 10q26.13 [CytoView hg38]
Mapping of homologs : NCBIIKZF5 [Mapview hg19]  IKZF5 [Mapview hg38]
OMIM606238   
Gene and transcription
Genbank (Entrez)AF230808 AI560579 AK023288 AK026626 AK055507
RefSeq transcript (Entrez)NM_001271840
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IKZF5
Cluster EST : UnigeneHs.501289 [ NCBI ]
CGAP (NCI)Hs.501289
Alternative Splicing GalleryENSG00000095574
Gene ExpressionIKZF5 [ NCBI-GEO ]   IKZF5 [ EBI - ARRAY_EXPRESS ]   IKZF5 [ SEEK ]   IKZF5 [ MEM ]
Gene Expression Viewer (FireBrowse)IKZF5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64376
GTEX Portal (Tissue expression)IKZF5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H5V7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H5V7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H5V7
Splice isoforms : SwissVarQ9H5V7
PhosPhoSitePlusQ9H5V7
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)IKZF5
DMDM Disease mutations64376
Blocks (Seattle)IKZF5
SuperfamilyQ9H5V7
Human Protein AtlasENSG00000095574
Peptide AtlasQ9H5V7
HPRD05873
IPIIPI00872098   
Protein Interaction databases
DIP (DOE-UCLA)Q9H5V7
IntAct (EBI)Q9H5V7
FunCoupENSG00000095574
BioGRIDIKZF5
STRING (EMBL)IKZF5
ZODIACIKZF5
Ontologies - Pathways
QuickGOQ9H5V7
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  nucleus  transcription, DNA-templated  zinc ion binding  protein domain specific binding  protein complex  protein heterooligomerization  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  nucleus  transcription, DNA-templated  zinc ion binding  protein domain specific binding  protein complex  protein heterooligomerization  
NDEx NetworkIKZF5
Atlas of Cancer Signalling NetworkIKZF5
Wikipedia pathwaysIKZF5
Orthology - Evolution
OrthoDB64376
GeneTree (enSembl)ENSG00000095574
Phylogenetic Trees/Animal Genes : TreeFamIKZF5
HOVERGENQ9H5V7
HOGENOMQ9H5V7
Homologs : HomoloGeneIKZF5
Homology/Alignments : Family Browser (UCSC)IKZF5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIKZF5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IKZF5
dbVarIKZF5
ClinVarIKZF5
1000_GenomesIKZF5 
Exome Variant ServerIKZF5
ExAC (Exome Aggregation Consortium)IKZF5 (select the gene name)
Genetic variants : HAPMAP64376
Genomic Variants (DGV)IKZF5 [DGVbeta]
DECIPHERIKZF5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIKZF5 
Mutations
ICGC Data PortalIKZF5 
TCGA Data PortalIKZF5 
Broad Tumor PortalIKZF5
OASIS PortalIKZF5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIKZF5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIKZF5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IKZF5
DgiDB (Drug Gene Interaction Database)IKZF5
DoCM (Curated mutations)IKZF5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IKZF5 (select a term)
intoGenIKZF5
Cancer3DIKZF5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606238   
Orphanet
MedgenIKZF5
Genetic Testing Registry IKZF5
NextProtQ9H5V7 [Medical]
TSGene64376
GENETestsIKZF5
Target ValidationIKZF5
Huge Navigator IKZF5 [HugePedia]
snp3D : Map Gene to Disease64376
BioCentury BCIQIKZF5
ClinGenIKZF5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64376
Chemical/Pharm GKB GenePA162391969
Clinical trialIKZF5
Miscellaneous
canSAR (ICR)IKZF5 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIKZF5
EVEXIKZF5
GoPubMedIKZF5
iHOPIKZF5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:11:09 CEST 2017

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