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IL10RA (interleukin 10 receptor subunit alpha)

Identity

Alias_namesIL10R
interleukin 10 receptor
Alias_symbol (synonym)HIL-10R
CDW210A
CD210a
CD210
Other aliasIL-10R1
HGNC (Hugo) IL10RA
LocusID (NCBI) 3587
Atlas_Id 46038
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 117986391 and ends at 118001483 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IL10RA (11q23.3) / WSB1 (17q11.1)PHLDB1 (11q23.3) / IL10RA (11q23.3)PHLDB1 11q23.3 / IL10RA 11q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL10RA   5964
LRG (Locus Reference Genomic)LRG_151
Cards
Entrez_Gene (NCBI)IL10RA  3587  interleukin 10 receptor subunit alpha
AliasesCD210; CD210a; CDW210A; HIL-10R; 
IL-10R1; IL10R
GeneCards (Weizmann)IL10RA
Ensembl hg19 (Hinxton)ENSG00000110324 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110324 [Gene_View]  chr11:117986391-118001483 [Contig_View]  IL10RA [Vega]
ICGC DataPortalENSG00000110324
TCGA cBioPortalIL10RA
AceView (NCBI)IL10RA
Genatlas (Paris)IL10RA
WikiGenes3587
SOURCE (Princeton)IL10RA
Genetics Home Reference (NIH)IL10RA
Genomic and cartography
GoldenPath hg38 (UCSC)IL10RA  -     chr11:117986391-118001483 +  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL10RA  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblIL10RA - 11q23.3 [CytoView hg19]  IL10RA - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBIIL10RA [Mapview hg19]  IL10RA [Mapview hg38]
OMIM146933   613148   
Gene and transcription
Genbank (Entrez)AB209626 AK291645 AK301260 AK301484 AK301492
RefSeq transcript (Entrez)NM_001558
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL10RA
Cluster EST : UnigeneHs.504035 [ NCBI ]
CGAP (NCI)Hs.504035
Alternative Splicing GalleryENSG00000110324
Gene ExpressionIL10RA [ NCBI-GEO ]   IL10RA [ EBI - ARRAY_EXPRESS ]   IL10RA [ SEEK ]   IL10RA [ MEM ]
Gene Expression Viewer (FireBrowse)IL10RA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3587
GTEX Portal (Tissue expression)IL10RA
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13651   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13651  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13651
Splice isoforms : SwissVarQ13651
PhosPhoSitePlusQ13651
Domains : Interpro (EBI)FN3_dom    Ig-like_fold   
Domain families : Pfam (Sanger)Tissue_fac (PF01108)   
Domain families : Pfam (NCBI)pfam01108   
Conserved Domain (NCBI)IL10RA
DMDM Disease mutations3587
Blocks (Seattle)IL10RA
PDB (SRS)1J7V    1LQS    1Y6K    1Y6M    1Y6N    5IXI   
PDB (PDBSum)1J7V    1LQS    1Y6K    1Y6M    1Y6N    5IXI   
PDB (IMB)1J7V    1LQS    1Y6K    1Y6M    1Y6N    5IXI   
PDB (RSDB)1J7V    1LQS    1Y6K    1Y6M    1Y6N    5IXI   
Structural Biology KnowledgeBase1J7V    1LQS    1Y6K    1Y6M    1Y6N    5IXI   
SCOP (Structural Classification of Proteins)1J7V    1LQS    1Y6K    1Y6M    1Y6N    5IXI   
CATH (Classification of proteins structures)1J7V    1LQS    1Y6K    1Y6M    1Y6N    5IXI   
SuperfamilyQ13651
Human Protein AtlasENSG00000110324
Peptide AtlasQ13651
HPRD00911
IPIIPI00014417   IPI01012398   IPI01011897   IPI01010927   IPI00980289   IPI00978548   
Protein Interaction databases
DIP (DOE-UCLA)Q13651
IntAct (EBI)Q13651
FunCoupENSG00000110324
BioGRIDIL10RA
STRING (EMBL)IL10RA
ZODIACIL10RA
Ontologies - Pathways
QuickGOQ13651
Ontology : AmiGOsignal transducer activity  receptor activity  interleukin-10 receptor activity  protein binding  plasma membrane  plasma membrane  integral component of membrane  cytokine-mediated signaling pathway  interleukin-10 binding  response to lipopolysaccharide  regulation of synapse organization  
Ontology : EGO-EBIsignal transducer activity  receptor activity  interleukin-10 receptor activity  protein binding  plasma membrane  plasma membrane  integral component of membrane  cytokine-mediated signaling pathway  interleukin-10 binding  response to lipopolysaccharide  regulation of synapse organization  
Pathways : BIOCARTAIL-10 Anti-inflammatory Signaling Pathway [Genes]   
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway    Toxoplasmosis    Tuberculosis    Epstein-Barr virus infection   
NDEx NetworkIL10RA
Atlas of Cancer Signalling NetworkIL10RA
Wikipedia pathwaysIL10RA
Orthology - Evolution
OrthoDB3587
GeneTree (enSembl)ENSG00000110324
Phylogenetic Trees/Animal Genes : TreeFamIL10RA
HOVERGENQ13651
HOGENOMQ13651
Homologs : HomoloGeneIL10RA
Homology/Alignments : Family Browser (UCSC)IL10RA
Gene fusions - Rearrangements
Fusion : MitelmanPHLDB1/IL10RA [11q23.3/11q23.3]  [t(11;11)(q23;q23)]  
Fusion: TCGAPHLDB1 11q23.3 IL10RA 11q23.3 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL10RA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL10RA
dbVarIL10RA
ClinVarIL10RA
1000_GenomesIL10RA 
Exome Variant ServerIL10RA
ExAC (Exome Aggregation Consortium)IL10RA (select the gene name)
Genetic variants : HAPMAP3587
Genomic Variants (DGV)IL10RA [DGVbeta]
DECIPHERIL10RA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL10RA 
Mutations
ICGC Data PortalIL10RA 
TCGA Data PortalIL10RA 
Broad Tumor PortalIL10RA
OASIS PortalIL10RA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL10RA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL10RA
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
LOVD (Leiden Open Variation Database)TBsLVD Tuberculosis susceptibility Locus Variation Database
BioMutasearch IL10RA
DgiDB (Drug Gene Interaction Database)IL10RA
DoCM (Curated mutations)IL10RA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL10RA (select a term)
intoGenIL10RA
Cancer3DIL10RA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM146933    613148   
Orphanet19277   
MedgenIL10RA
Genetic Testing Registry IL10RA
NextProtQ13651 [Medical]
TSGene3587
GENETestsIL10RA
Target ValidationIL10RA
Huge Navigator IL10RA [HugePedia]
snp3D : Map Gene to Disease3587
BioCentury BCIQIL10RA
ClinGenIL10RA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3587
Chemical/Pharm GKB GenePA29779
Clinical trialIL10RA
Miscellaneous
canSAR (ICR)IL10RA (select the gene name)
Probes
Litterature
PubMed122 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL10RA
EVEXIL10RA
GoPubMedIL10RA
iHOPIL10RA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:03:52 CEST 2017

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