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IL13 (interleukin 13)

Identity

Other namesALRH
BHR1
IL-13
P600
HGNC (Hugo) IL13
LocusID (NCBI) 3596
Location 5q31.1
Location_base_pair Starts at 131993865 and ends at 131996801 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IL13   5973
Entrez_Gene (NCBI)IL13  3596  interleukin 13
Cards
GeneCards (Weizmann)IL13
Ensembl (Hinxton)ENSG00000169194 [Gene_View]  chr5:131993865-131996801 [Contig_View]  IL13 [Vega]
AceView (NCBI)IL13
Genatlas (Paris)IL13
SOURCE (Stanford)NM_002188
Genomic and cartography
GoldenPath (UCSC)IL13  -  5q31.1   chr5:131993865-131996801 +  5q31.1   [Description]    (hg19-Feb_2009)
EnsemblIL13 - 5q31.1 [CytoView]
Mapping of homologs : NCBIIL13 [Mapview]
OMIM147683   600807   607154   
Gene and transcription
Genbank (Entrez)AF043334 BC096138 BC096139 BC096140 BC096141
RefSeq transcript (SRS)NM_002188
RefSeq transcript (Entrez)NM_002188
RefSeq genomic (SRS)AC_000137 NC_000005 NC_018916 NG_012090 NT_034772 NW_001838952 NW_004078024
RefSeq genomic (Entrez)AC_000137 NC_000005 NC_018916 NG_012090 NT_034772 NW_001838952 NW_004078024
Consensus coding sequences : CCDS (NCBI)IL13
Cluster EST : UnigeneHs.845 [ SRS ] Hs.845 [ NCBI ]
CGAP (NCI)Hs.845
Alternative Splicing : Fast-db (Paris)GSHG0024229
Alternative Splicing GalleryENSG00000169194
Gene ExpressionIL13 [ NCBI-GEO ]   IL13 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP35225 (SRS) P35225 (Uniprot)
NextProtP35225
With graphics : InterProP35225
Splice isoforms : SwissVarP35225(Swissvar)
Domaine pattern : Prosite (SRS)INTERLEUKIN_4_13 (PS00838)   
Domaine pattern : Prosite (Expaxy)INTERLEUKIN_4_13 (PS00838)   
Domains : Interpro (SRS)4_helix_cytokine-like_core    4_helix_cytokine_core    Interleukin-13    Interleukin-4/-13_CS    Interleukin-4/13   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Interleukin-13    Interleukin-4/-13_CS    Interleukin-4/13   
Related proteins : CluSTrP35225
Domain families : Pfam (SRS)IL13 (PF03487)   
Domain families : Pfam (Sanger)IL13 (PF03487)   
Domain families : Pfam (NCBI)pfam03487   
Domain families : Smart (EMBL)IL4_13 (SM00190)  
DMDM3596
Blocks (Seattle)P35225
PDB (SRS)1GA3    1IJZ    1IK0    1J9U    3BPO    3G6D    3ITR    3ITS    3L5W    3L5X    3L5Y    3LB6   
PDB (PDBSum)1GA3    1IJZ    1IK0    1J9U    3BPO    3G6D    3ITR    3ITS    3L5W    3L5X    3L5Y    3LB6   
PDB (IMB)1GA3    1IJZ    1IK0    1J9U    3BPO    3G6D    3ITR    3ITS    3L5W    3L5X    3L5Y    3LB6   
PDB (RSDB)1GA3    1IJZ    1IK0    1J9U    3BPO    3G6D    3ITR    3ITS    3L5W    3L5X    3L5Y    3LB6   
Human Protein AtlasENSG00000169194
HPRD00981
IPIIPI00807607   
Protein Interaction databases
DIP (DOE-UCLA)P35225
IntAct (EBI)P35225
FunCoupENSG00000169194
REACTOMEIL13
Protein Interaction Database3596
BioGRIDIL13
InParanoidP35225
Interologous Interaction database P35225
IntegromeDBIL13
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)IL13
SNP (GeneSNP Utah)IL13
SNP : HGBaseIL13
Genetic variants : HAPMAPIL13
Somatic Mutations in Cancer : COSMICIL13 
CONAN: Copy Number AnalysisIL13 
Mutations and Diseases : HGMDIL13
OMIM147683    600807    607154   
GENETests147683    600807    607154   
Disease Genetic AssociationIL13
Huge Navigator IL13 [HugePedia]  IL13 [HugeCancerGEM]
Genomic VariantsIL13  IL13 [DGVbeta]
snp3D : Map Gene to Disease3596
General knowledge
Homologs : HomoloGeneIL13
Homology/Alignments : Family Browser (UCSC)IL13
Phylogenetic Trees/Animal Genes : TreeFamIL13
Chemical/Protein Interactions : CTD3596
Chemical/Pharm GKB GenePA199
Clinical trialIL13
Cancer Resource (Charite)ENSG00000169194
Ontology : AmiGOpositive regulation of immunoglobulin production  cytokine activity  interleukin-13 receptor binding  protein binding  extracellular region  extracellular space  cytoplasm  cellular component movement  inflammatory response  immune response  signal transduction  cell-cell signaling  external side of plasma membrane  regulation of proton transport  positive regulation of B cell proliferation  response to lipopolysaccharide  response to nicotine  positive regulation of macrophage activation  response to ethanol  positive regulation of smooth muscle cell proliferation  positive regulation of protein secretion  positive regulation of release of sequestered calcium ion into cytosol  cellular response to mechanical stimulus  cellular response to cytokine stimulus  negative regulation of transforming growth factor beta production  negative regulation of lung ciliated cell differentiation  positive regulation of lung goblet cell differentiation  
Ontology : EGO-EBIpositive regulation of immunoglobulin production  cytokine activity  interleukin-13 receptor binding  protein binding  extracellular region  extracellular space  cytoplasm  cellular component movement  inflammatory response  immune response  signal transduction  cell-cell signaling  external side of plasma membrane  regulation of proton transport  positive regulation of B cell proliferation  response to lipopolysaccharide  response to nicotine  positive regulation of macrophage activation  response to ethanol  positive regulation of smooth muscle cell proliferation  positive regulation of protein secretion  positive regulation of release of sequestered calcium ion into cytosol  cellular response to mechanical stimulus  cellular response to cytokine stimulus  negative regulation of transforming growth factor beta production  negative regulation of lung ciliated cell differentiation  positive regulation of lung goblet cell differentiation  
Pathways : BIOCARTACytokines and Inflammatory Response [Genes]    Dendritic cells in regulating TH1 and TH2 Development [Genes]    Cytokine Network [Genes]    GATA3 participate in activating the Th2 cytokine genes expression [Genes]   
Pathways : KEGGFc epsilon RI signaling pathwayJak-STAT signaling pathwayCytokine-cytokine receptor interaction
Other databases
Probes
Litterature
PubMed438 Pubmed reference(s) in Entrez
PubGeneIL13
iHOPIL13
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:19:18 CEST 2013
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