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IL15RA (interleukin 15 receptor subunit alpha)

Identity

Alias (NCBI)CD215
HGNC (Hugo) IL15RA
HGNC Alias symbCD215
IL-15RA
HGNC Previous nameinterleukin 15 receptor, alpha
LocusID (NCBI) 3601
Atlas_Id 43964
Location 10p15.1  [Link to chromosome band 10p15]
Location_base_pair Starts at 5952384 and ends at 5977543 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)IL15RA   5978
Cards
Entrez_Gene (NCBI)IL15RA    interleukin 15 receptor subunit alpha
AliasesCD215
GeneCards (Weizmann)IL15RA
Ensembl hg19 (Hinxton)ENSG00000134470 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134470 [Gene_View]  ENSG00000134470 [Sequence]  chr10:5952384-5977543 [Contig_View]  IL15RA [Vega]
ICGC DataPortalENSG00000134470
TCGA cBioPortalIL15RA
AceView (NCBI)IL15RA
Genatlas (Paris)IL15RA
SOURCE (Princeton)IL15RA
Genetics Home Reference (NIH)IL15RA
Genomic and cartography
GoldenPath hg38 (UCSC)IL15RA  -     chr10:5952384-5977543 -  10p15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL15RA  -     10p15.1   [Description]    (hg19-Feb_2009)
GoldenPathIL15RA - 10p15.1 [CytoView hg19]  IL15RA - 10p15.1 [CytoView hg38]
ImmunoBaseENSG00000134470
Genome Data Viewer NCBIIL15RA [Mapview hg19]  
OMIM601070   
Gene and transcription
Genbank (Entrez)AA847313 AF035279 AK304211 BC065506 BC074726
RefSeq transcript (Entrez)NM_001243539 NM_001256765 NM_001351095 NM_001351096 NM_001351097 NM_002189 NM_172200
Consensus coding sequences : CCDS (NCBI)IL15RA
Gene ExpressionIL15RA [ NCBI-GEO ]   IL15RA [ EBI - ARRAY_EXPRESS ]   IL15RA [ SEEK ]   IL15RA [ MEM ]
Gene Expression Viewer (FireBrowse)IL15RA [ Firebrowse - Broad ]
GenevisibleExpression of IL15RA in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3601
GTEX Portal (Tissue expression)IL15RA
Human Protein AtlasENSG00000134470-IL15RA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13261   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13261  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13261
PhosPhoSitePlusQ13261
Domaine pattern : Prosite (Expaxy)SUSHI (PS50923)   
Domains : Interpro (EBI)IL15RA    Sushi/SCR/CCP_sf    Sushi_SCR_CCP_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)CCP (SM00032)  
Conserved Domain (NCBI)IL15RA
PDB (RSDB)2ERS    2Z3Q    2Z3R    4GS7   
PDB Europe2ERS    2Z3Q    2Z3R    4GS7   
PDB (PDBSum)2ERS    2Z3Q    2Z3R    4GS7   
PDB (IMB)2ERS    2Z3Q    2Z3R    4GS7   
Structural Biology KnowledgeBase2ERS    2Z3Q    2Z3R    4GS7   
SCOP (Structural Classification of Proteins)2ERS    2Z3Q    2Z3R    4GS7   
CATH (Classification of proteins structures)2ERS    2Z3Q    2Z3R    4GS7   
SuperfamilyQ13261
AlphaFold pdb e-kbQ13261   
Human Protein Atlas [tissue]ENSG00000134470-IL15RA [tissue]
HPRD03045
Protein Interaction databases
DIP (DOE-UCLA)Q13261
IntAct (EBI)Q13261
BioGRIDIL15RA
STRING (EMBL)IL15RA
ZODIACIL15RA
Ontologies - Pathways
QuickGOQ13261
Ontology : AmiGOGolgi membrane  cytokine receptor activity  protein binding  extracellular space  endosome  endoplasmic reticulum membrane  plasma membrane  plasma membrane  cell surface  integral component of membrane  protein kinase binding  cytoplasmic vesicle membrane  nuclear membrane  positive regulation of natural killer cell differentiation  interleukin-15-mediated signaling pathway  interleukin-15-mediated signaling pathway  interleukin-15-mediated signaling pathway  interleukin-15 receptor activity  interleukin-15 receptor activity  positive regulation of phagocytosis  
Ontology : EGO-EBIGolgi membrane  cytokine receptor activity  protein binding  extracellular space  endosome  endoplasmic reticulum membrane  plasma membrane  plasma membrane  cell surface  integral component of membrane  protein kinase binding  cytoplasmic vesicle membrane  nuclear membrane  positive regulation of natural killer cell differentiation  interleukin-15-mediated signaling pathway  interleukin-15-mediated signaling pathway  interleukin-15-mediated signaling pathway  interleukin-15 receptor activity  interleukin-15 receptor activity  positive regulation of phagocytosis  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway    Intestinal immune network for IgA production    HTLV-I infection   
NDEx NetworkIL15RA
Atlas of Cancer Signalling NetworkIL15RA
Wikipedia pathwaysIL15RA
Orthology - Evolution
OrthoDB3601
GeneTree (enSembl)ENSG00000134470
Phylogenetic Trees/Animal Genes : TreeFamIL15RA
Homologs : HomoloGeneIL15RA
Homology/Alignments : Family Browser (UCSC)IL15RA
Gene fusions - Rearrangements
Fusion : QuiverIL15RA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL15RA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL15RA
dbVarIL15RA
ClinVarIL15RA
MonarchIL15RA
1000_GenomesIL15RA 
Exome Variant ServerIL15RA
GNOMAD BrowserENSG00000134470
Varsome BrowserIL15RA
ACMGIL15RA variants
VarityQ13261
Genomic Variants (DGV)IL15RA [DGVbeta]
DECIPHERIL15RA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL15RA 
Mutations
ICGC Data PortalIL15RA 
TCGA Data PortalIL15RA 
Broad Tumor PortalIL15RA
OASIS PortalIL15RA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL15RA  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIL15RA
Mutations and Diseases : HGMDIL15RA
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaIL15RA
DgiDB (Drug Gene Interaction Database)IL15RA
DoCM (Curated mutations)IL15RA
CIViC (Clinical Interpretations of Variants in Cancer)IL15RA
Cancer3DIL15RA
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601070   
Orphanet
DisGeNETIL15RA
MedgenIL15RA
Genetic Testing Registry IL15RA
NextProtQ13261 [Medical]
GENETestsIL15RA
Target ValidationIL15RA
Huge Navigator IL15RA [HugePedia]
ClinGenIL15RA
Clinical trials, drugs, therapy
MyCancerGenomeIL15RA
Protein Interactions : CTDIL15RA
Pharm GKB GenePA29791
PharosQ13261
Clinical trialIL15RA
Miscellaneous
canSAR (ICR)IL15RA
HarmonizomeIL15RA
DataMed IndexIL15RA
Probes
Litterature
PubMed103 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIL15RA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:13:43 CEST 2021

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