Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3603
MIM: 603035
HGNC: 5980
Ensembl: ENSG00000172349
Variants:
dbSNP: 3603
ClinVar: 3603
TCGA: ENSG00000172349
COSMIC: IL16
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Cytokine Signaling in Immune system | REACTOME | R-HSA-1280215 |
| Signaling by Interleukins | REACTOME | R-HSA-449147 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713176 | Platinum compounds | Chemical | ClinicalAnnotation | associated | PD | 27498158 | |
| PA443622 | Carcinoma, Non-Small-Cell Lung | Disease | ClinicalAnnotation | associated | PD | 27498158 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37853768 | 2024 | Association of IL-6 rs1800795, but not TNF-α rs1800629, and IL-1β rs16944 polymorphisms' genotypes with recovery of ischemic stroke patients following thrombolysis. | 0 |
| 38148080 | 2024 | The Significant Contribution of Interleukin-16 Genotypes, Smoking, Alcohol Drinking, and Helicobacter Pylori Infection to Gastric Cancer. | 1 |
| 38380651 | 2024 | Mycobacterium tuberculosis hijacks host macrophages-derived interleukin 16 to block phagolysosome maturation for enhancing intracellular growth. | 1 |
| 38544694 | 2024 | Interleukin-16 is increased in obesity and alters adipogenesis and inflammation in vitro. | 0 |
| 37853768 | 2024 | Association of IL-6 rs1800795, but not TNF-α rs1800629, and IL-1β rs16944 polymorphisms' genotypes with recovery of ischemic stroke patients following thrombolysis. | 0 |
| 38148080 | 2024 | The Significant Contribution of Interleukin-16 Genotypes, Smoking, Alcohol Drinking, and Helicobacter Pylori Infection to Gastric Cancer. | 1 |
| 38380651 | 2024 | Mycobacterium tuberculosis hijacks host macrophages-derived interleukin 16 to block phagolysosome maturation for enhancing intracellular growth. | 1 |
| 38544694 | 2024 | Interleukin-16 is increased in obesity and alters adipogenesis and inflammation in vitro. | 0 |
| 36946317 | 2023 | IL16 and factor V gene variations are associated with asparaginase-related thrombosis in childhood acute lymphoblastic leukemia patients. | 0 |
| 37138138 | 2023 | Interleukin-16 genetic polymorphisms in Guangxi Chinese with hepatitis B virus-related liver cirrhosis. | 0 |
| 37170270 | 2023 | Serum concentrations of IL-16 and its genetic polymorphism rs4778889 affect the susceptibility and severity of endometriosis in Nigerian women. | 1 |
| 37259724 | 2023 | The relationship of promoter methylation of calcium voltage-gated channel alpha 1 and interleukin-16 to primary osteoarthritis. | 1 |
| 37263073 | 2023 | Elevated expression of interleukin 16 in chronic lymphocytic leukemia is associated with disease burden and abnormal immune microenvironment. | 1 |
| 36946317 | 2023 | IL16 and factor V gene variations are associated with asparaginase-related thrombosis in childhood acute lymphoblastic leukemia patients. | 0 |
| 37138138 | 2023 | Interleukin-16 genetic polymorphisms in Guangxi Chinese with hepatitis B virus-related liver cirrhosis. | 0 |
Citation
Dessen P
IL16 (interleukin 16)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40944/il16
