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IL16 (interleukin 16)

Identity

Alias_namesinterleukin 16 (lymphocyte chemoattractant factor)
Alias_symbol (synonym)LCF
IL-16
prIL-16
HsT19289
FLJ42735
FLJ16806
Other aliasNIL16
PRIL16
HGNC (Hugo) IL16
LocusID (NCBI) 3603
Atlas_Id 40944
Location 15q25.1  [Link to chromosome band 15q25]
Location_base_pair Starts at 81196878 and ends at 81312763 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL16   5980
Cards
Entrez_Gene (NCBI)IL16  3603  interleukin 16
AliasesLCF; NIL16; PRIL16; prIL-16
GeneCards (Weizmann)IL16
Ensembl hg19 (Hinxton)ENSG00000172349 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172349 [Gene_View]  chr15:81196878-81312763 [Contig_View]  IL16 [Vega]
ICGC DataPortalENSG00000172349
TCGA cBioPortalIL16
AceView (NCBI)IL16
Genatlas (Paris)IL16
WikiGenes3603
SOURCE (Princeton)IL16
Genetics Home Reference (NIH)IL16
Genomic and cartography
GoldenPath hg38 (UCSC)IL16  -     chr15:81196878-81312763 +  15q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL16  -     15q25.1   [Description]    (hg19-Feb_2009)
EnsemblIL16 - 15q25.1 [CytoView hg19]  IL16 - 15q25.1 [CytoView hg38]
Mapping of homologs : NCBIIL16 [Mapview hg19]  IL16 [Mapview hg38]
OMIM603035   
Gene and transcription
Genbank (Entrez)AF053412 AK124565 AK124725 AK126222 AK128740
RefSeq transcript (Entrez)NM_001172128 NM_004513 NM_172217
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL16
Cluster EST : UnigeneHs.459095 [ NCBI ]
CGAP (NCI)Hs.459095
Alternative Splicing GalleryENSG00000172349
Gene ExpressionIL16 [ NCBI-GEO ]   IL16 [ EBI - ARRAY_EXPRESS ]   IL16 [ SEEK ]   IL16 [ MEM ]
Gene Expression Viewer (FireBrowse)IL16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3603
GTEX Portal (Tissue expression)IL16
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14005   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14005  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14005
Splice isoforms : SwissVarQ14005
PhosPhoSitePlusQ14005
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)   
Domains : Interpro (EBI)IL-16    PDZ   
Domain families : Pfam (Sanger)PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00595   
Domain families : Smart (EMBL)PDZ (SM00228)  
Conserved Domain (NCBI)IL16
DMDM Disease mutations3603
Blocks (Seattle)IL16
PDB (SRS)1I16    1X6D    5FB8   
PDB (PDBSum)1I16    1X6D    5FB8   
PDB (IMB)1I16    1X6D    5FB8   
PDB (RSDB)1I16    1X6D    5FB8   
Structural Biology KnowledgeBase1I16    1X6D    5FB8   
SCOP (Structural Classification of Proteins)1I16    1X6D    5FB8   
CATH (Classification of proteins structures)1I16    1X6D    5FB8   
SuperfamilyQ14005
Human Protein AtlasENSG00000172349
Peptide AtlasQ14005
HPRD04329
IPIIPI00442038   IPI00853332   IPI00289966   IPI01011592   IPI01015778   IPI00216870   IPI01014529   IPI01010640   IPI00470934   
Protein Interaction databases
DIP (DOE-UCLA)Q14005
IntAct (EBI)Q14005
FunCoupENSG00000172349
BioGRIDIL16
STRING (EMBL)IL16
ZODIACIL16
Ontologies - Pathways
QuickGOQ14005
Ontology : AmiGOcytokine activity  extracellular region  extracellular space  cytosol  cytosol  plasma membrane  transcription, DNA-templated  regulation of transcription, DNA-templated  immune response  viral process  nuclear speck  leukocyte chemotaxis  CD4 receptor binding  induction of positive chemotaxis  regulation of calcium ion transport  
Ontology : EGO-EBIcytokine activity  extracellular region  extracellular space  cytosol  cytosol  plasma membrane  transcription, DNA-templated  regulation of transcription, DNA-templated  immune response  viral process  nuclear speck  leukocyte chemotaxis  CD4 receptor binding  induction of positive chemotaxis  regulation of calcium ion transport  
Pathways : BIOCARTACytokine Network [Genes]   
NDEx NetworkIL16
Atlas of Cancer Signalling NetworkIL16
Wikipedia pathwaysIL16
Orthology - Evolution
OrthoDB3603
GeneTree (enSembl)ENSG00000172349
Phylogenetic Trees/Animal Genes : TreeFamIL16
HOVERGENQ14005
HOGENOMQ14005
Homologs : HomoloGeneIL16
Homology/Alignments : Family Browser (UCSC)IL16
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL16
dbVarIL16
ClinVarIL16
1000_GenomesIL16 
Exome Variant ServerIL16
ExAC (Exome Aggregation Consortium)IL16 (select the gene name)
Genetic variants : HAPMAP3603
Genomic Variants (DGV)IL16 [DGVbeta]
DECIPHERIL16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL16 
Mutations
ICGC Data PortalIL16 
TCGA Data PortalIL16 
Broad Tumor PortalIL16
OASIS PortalIL16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL16
DgiDB (Drug Gene Interaction Database)IL16
DoCM (Curated mutations)IL16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL16 (select a term)
intoGenIL16
Cancer3DIL16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603035   
Orphanet
MedgenIL16
Genetic Testing Registry IL16
NextProtQ14005 [Medical]
TSGene3603
GENETestsIL16
Huge Navigator IL16 [HugePedia]
snp3D : Map Gene to Disease3603
BioCentury BCIQIL16
ClinGenIL16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3603
Chemical/Pharm GKB GenePA29793
Clinical trialIL16
Miscellaneous
canSAR (ICR)IL16 (select the gene name)
Probes
Litterature
PubMed142 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL16
EVEXIL16
GoPubMedIL16
iHOPIL16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:20:17 CEST 2017

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