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IL17D (interleukin 17D)

Identity

Alias_symbol (synonym)IL-22
IL-27
IL-17D
IL27
FLJ30846
Other alias
HGNC (Hugo) IL17D
LocusID (NCBI) 53342
Atlas_Id 52608
Location 13q12.11  [Link to chromosome band 13q12]
Location_base_pair Starts at 20703343 and ends at 20723098 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IL17D (13q12.11) / IFT88 (13q12.11)IL17D 13q12.11 / IFT88 13q12.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(13;13)(q12;q12) IL17D/IFT88

External links

Nomenclature
HGNC (Hugo)IL17D   5984
Cards
Entrez_Gene (NCBI)IL17D  53342  interleukin 17D
AliasesIL-17D
GeneCards (Weizmann)IL17D
Ensembl hg19 (Hinxton)ENSG00000172458 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172458 [Gene_View]  chr13:20703343-20723098 [Contig_View]  IL17D [Vega]
ICGC DataPortalENSG00000172458
TCGA cBioPortalIL17D
AceView (NCBI)IL17D
Genatlas (Paris)IL17D
WikiGenes53342
SOURCE (Princeton)IL17D
Genetics Home Reference (NIH)IL17D
Genomic and cartography
GoldenPath hg38 (UCSC)IL17D  -     chr13:20703343-20723098 +  13q12.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL17D  -     13q12.11   [Description]    (hg19-Feb_2009)
EnsemblIL17D - 13q12.11 [CytoView hg19]  IL17D - 13q12.11 [CytoView hg38]
Mapping of homologs : NCBIIL17D [Mapview hg19]  IL17D [Mapview hg38]
OMIM607587   
Gene and transcription
Genbank (Entrez)AF458062 AF479775 AK123964 AY078238 AY359113
RefSeq transcript (Entrez)NM_138284
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL17D
Cluster EST : UnigeneHs.655142 [ NCBI ]
CGAP (NCI)Hs.655142
Alternative Splicing GalleryENSG00000172458
Gene ExpressionIL17D [ NCBI-GEO ]   IL17D [ EBI - ARRAY_EXPRESS ]   IL17D [ SEEK ]   IL17D [ MEM ]
Gene Expression Viewer (FireBrowse)IL17D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53342
GTEX Portal (Tissue expression)IL17D
Human Protein AtlasENSG00000172458-IL17D [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TAD2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TAD2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TAD2
Splice isoforms : SwissVarQ8TAD2
PhosPhoSitePlusQ8TAD2
Domains : Interpro (EBI)Cystine-knot_cytokine    IL-17_chr    IL-17_fam   
Domain families : Pfam (Sanger)IL17 (PF06083)   
Domain families : Pfam (NCBI)pfam06083   
Conserved Domain (NCBI)IL17D
DMDM Disease mutations53342
Blocks (Seattle)IL17D
SuperfamilyQ8TAD2
Human Protein Atlas [tissue]ENSG00000172458-IL17D [tissue]
Peptide AtlasQ8TAD2
HPRD16251
IPIIPI00152038   
Protein Interaction databases
DIP (DOE-UCLA)Q8TAD2
IntAct (EBI)Q8TAD2
FunCoupENSG00000172458
BioGRIDIL17D
STRING (EMBL)IL17D
ZODIACIL17D
Ontologies - Pathways
QuickGOQ8TAD2
Ontology : AmiGOcytokine activity  extracellular space  inflammatory response  regulation of receptor activity  positive regulation of granulocyte macrophage colony-stimulating factor production  positive regulation of interleukin-6 production  positive regulation of interleukin-8 production  protein homodimerization activity  receptor ligand activity  positive regulation of cytokine production involved in inflammatory response  negative regulation of hemopoiesis  
Ontology : EGO-EBIcytokine activity  extracellular space  inflammatory response  regulation of receptor activity  positive regulation of granulocyte macrophage colony-stimulating factor production  positive regulation of interleukin-6 production  positive regulation of interleukin-8 production  protein homodimerization activity  receptor ligand activity  positive regulation of cytokine production involved in inflammatory response  negative regulation of hemopoiesis  
NDEx NetworkIL17D
Atlas of Cancer Signalling NetworkIL17D
Wikipedia pathwaysIL17D
Orthology - Evolution
OrthoDB53342
GeneTree (enSembl)ENSG00000172458
Phylogenetic Trees/Animal Genes : TreeFamIL17D
HOVERGENQ8TAD2
HOGENOMQ8TAD2
Homologs : HomoloGeneIL17D
Homology/Alignments : Family Browser (UCSC)IL17D
Gene fusions - Rearrangements
Fusion : MitelmanIL17D/IFT88 [13q12.11/13q12.11]  
Fusion: TCGA_MDACCIL17D 13q12.11 IFT88 13q12.11 SKCM
Fusion PortalIL17D 13q12.11 IFT88 13q12.11 SKCM
Fusion : QuiverIL17D
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL17D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL17D
dbVarIL17D
ClinVarIL17D
1000_GenomesIL17D 
Exome Variant ServerIL17D
ExAC (Exome Aggregation Consortium)ENSG00000172458
GNOMAD BrowserENSG00000172458
Genetic variants : HAPMAP53342
Genomic Variants (DGV)IL17D [DGVbeta]
DECIPHERIL17D [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL17D 
Mutations
ICGC Data PortalIL17D 
TCGA Data PortalIL17D 
Broad Tumor PortalIL17D
OASIS PortalIL17D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL17D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL17D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL17D
DgiDB (Drug Gene Interaction Database)IL17D
DoCM (Curated mutations)IL17D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL17D (select a term)
intoGenIL17D
Cancer3DIL17D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607587   
Orphanet
DisGeNETIL17D
MedgenIL17D
Genetic Testing Registry IL17D
NextProtQ8TAD2 [Medical]
TSGene53342
GENETestsIL17D
Target ValidationIL17D
Huge Navigator IL17D [HugePedia]
snp3D : Map Gene to Disease53342
BioCentury BCIQIL17D
ClinGenIL17D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD53342
Chemical/Pharm GKB GenePA29798
Clinical trialIL17D
Miscellaneous
canSAR (ICR)IL17D (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL17D
EVEXIL17D
GoPubMedIL17D
iHOPIL17D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jun 18 19:25:42 CEST 2018
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