Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IL17RA (interleukin 17 receptor A)

Identity

Alias_namesIL17R
interleukin 17 receptor
Alias_symbol (synonym)hIL-17R
IL-17RA
CDw217
CD217
Other aliasCANDF5
IMD51
HGNC (Hugo) IL17RA
LocusID (NCBI) 23765
Atlas_Id 53729
Location 22q11.1  [Link to chromosome band 22q11]
Location_base_pair Starts at 17084959 and ends at 17115694 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CECR7 (22q11.1) / IL17RA (22q11.1)IL17RA (22q11.1) / IL17RA (22q11.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL17RA   5985
LRG (Locus Reference Genomic)LRG_355
Cards
Entrez_Gene (NCBI)IL17RA  23765  interleukin 17 receptor A
AliasesCANDF5; CD217; CDw217; IL-17RA; 
IL17R; IMD51; hIL-17R
GeneCards (Weizmann)IL17RA
Ensembl hg19 (Hinxton)ENSG00000177663 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177663 [Gene_View]  chr22:17084959-17115694 [Contig_View]  IL17RA [Vega]
ICGC DataPortalENSG00000177663
TCGA cBioPortalIL17RA
AceView (NCBI)IL17RA
Genatlas (Paris)IL17RA
WikiGenes23765
SOURCE (Princeton)IL17RA
Genetics Home Reference (NIH)IL17RA
Genomic and cartography
GoldenPath hg38 (UCSC)IL17RA  -     chr22:17084959-17115694 +  22q11.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL17RA  -     22q11.1   [Description]    (hg19-Feb_2009)
EnsemblIL17RA - 22q11.1 [CytoView hg19]  IL17RA - 22q11.1 [CytoView hg38]
Mapping of homologs : NCBIIL17RA [Mapview hg19]  IL17RA [Mapview hg38]
OMIM605461   613953   
Gene and transcription
Genbank (Entrez)AF021799 AK056836 AK093772 BC011624 BC012071
RefSeq transcript (Entrez)NM_001289905 NM_014339
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL17RA
Cluster EST : UnigeneHs.48353 [ NCBI ]
CGAP (NCI)Hs.48353
Alternative Splicing GalleryENSG00000177663
Gene ExpressionIL17RA [ NCBI-GEO ]   IL17RA [ EBI - ARRAY_EXPRESS ]   IL17RA [ SEEK ]   IL17RA [ MEM ]
Gene Expression Viewer (FireBrowse)IL17RA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23765
GTEX Portal (Tissue expression)IL17RA
Human Protein AtlasENSG00000177663-IL17RA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96F46   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96F46  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96F46
Splice isoforms : SwissVarQ96F46
PhosPhoSitePlusQ96F46
Domaine pattern : Prosite (Expaxy)SEFIR (PS51534)   
Domains : Interpro (EBI)IL17R_fnIII_D1    SEFIR_dom   
Domain families : Pfam (Sanger)IL17R_fnIII_D1 (PF16556)    SEFIR (PF08357)   
Domain families : Pfam (NCBI)pfam16556    pfam08357   
Conserved Domain (NCBI)IL17RA
DMDM Disease mutations23765
Blocks (Seattle)IL17RA
PDB (SRS)3JVF    4HSA    4NUX   
PDB (PDBSum)3JVF    4HSA    4NUX   
PDB (IMB)3JVF    4HSA    4NUX   
PDB (RSDB)3JVF    4HSA    4NUX   
Structural Biology KnowledgeBase3JVF    4HSA    4NUX   
SCOP (Structural Classification of Proteins)3JVF    4HSA    4NUX   
CATH (Classification of proteins structures)3JVF    4HSA    4NUX   
SuperfamilyQ96F46
Human Protein Atlas [tissue]ENSG00000177663-IL17RA [tissue]
Peptide AtlasQ96F46
HPRD10399
IPIIPI00304993   IPI00853217   
Protein Interaction databases
DIP (DOE-UCLA)Q96F46
IntAct (EBI)Q96F46
FunCoupENSG00000177663
BioGRIDIL17RA
STRING (EMBL)IL17RA
ZODIACIL17RA
Ontologies - Pathways
QuickGOQ96F46
Ontology : AmiGOreceptor binding  protein binding  extracellular region  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  cytokine-mediated signaling pathway  interleukin-17 receptor activity  interleukin-17 receptor activity  positive regulation of interleukin-23 production  defense response to fungus  granulocyte chemotaxis  fibroblast activation  positive regulation of cytokine production involved in inflammatory response  positive regulation of interleukin-5 secretion  positive regulation of interleukin-13 secretion  
Ontology : EGO-EBIreceptor binding  protein binding  extracellular region  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  cytokine-mediated signaling pathway  interleukin-17 receptor activity  interleukin-17 receptor activity  positive regulation of interleukin-23 production  defense response to fungus  granulocyte chemotaxis  fibroblast activation  positive regulation of cytokine production involved in inflammatory response  positive regulation of interleukin-5 secretion  positive regulation of interleukin-13 secretion  
Pathways : KEGGCytokine-cytokine receptor interaction   
NDEx NetworkIL17RA
Atlas of Cancer Signalling NetworkIL17RA
Wikipedia pathwaysIL17RA
Orthology - Evolution
OrthoDB23765
GeneTree (enSembl)ENSG00000177663
Phylogenetic Trees/Animal Genes : TreeFamIL17RA
HOVERGENQ96F46
HOGENOMQ96F46
Homologs : HomoloGeneIL17RA
Homology/Alignments : Family Browser (UCSC)IL17RA
Gene fusions - Rearrangements
Tumor Fusion PortalIL17RA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL17RA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL17RA
dbVarIL17RA
ClinVarIL17RA
1000_GenomesIL17RA 
Exome Variant ServerIL17RA
ExAC (Exome Aggregation Consortium)ENSG00000177663
GNOMAD BrowserENSG00000177663
Genetic variants : HAPMAP23765
Genomic Variants (DGV)IL17RA [DGVbeta]
DECIPHERIL17RA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL17RA 
Mutations
ICGC Data PortalIL17RA 
TCGA Data PortalIL17RA 
Broad Tumor PortalIL17RA
OASIS PortalIL17RA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL17RA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL17RA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch IL17RA
DgiDB (Drug Gene Interaction Database)IL17RA
DoCM (Curated mutations)IL17RA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL17RA (select a term)
intoGenIL17RA
Cancer3DIL17RA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605461    613953   
Orphanet432   
DisGeNETIL17RA
MedgenIL17RA
Genetic Testing Registry IL17RA
NextProtQ96F46 [Medical]
TSGene23765
GENETestsIL17RA
Target ValidationIL17RA
Huge Navigator IL17RA [HugePedia]
snp3D : Map Gene to Disease23765
BioCentury BCIQIL17RA
ClinGenIL17RA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23765
Chemical/Pharm GKB GenePA29801
Clinical trialIL17RA
Miscellaneous
canSAR (ICR)IL17RA (select the gene name)
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL17RA
EVEXIL17RA
GoPubMedIL17RA
iHOPIL17RA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:17:38 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.