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IL18BP (interleukin 18 binding protein)

Identity

Alias_symbol (synonym)IL18BPa
Other alias
HGNC (Hugo) IL18BP
LocusID (NCBI) 10068
Atlas_Id 51571
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 71998912 and ends at 72002528 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL18BP   5987
Cards
Entrez_Gene (NCBI)IL18BP  10068  interleukin 18 binding protein
AliasesIL18BPa
GeneCards (Weizmann)IL18BP
Ensembl hg19 (Hinxton)ENSG00000137496 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137496 [Gene_View]  chr11:71998912-72002528 [Contig_View]  IL18BP [Vega]
ICGC DataPortalENSG00000137496
TCGA cBioPortalIL18BP
AceView (NCBI)IL18BP
Genatlas (Paris)IL18BP
WikiGenes10068
SOURCE (Princeton)IL18BP
Genetics Home Reference (NIH)IL18BP
Genomic and cartography
GoldenPath hg38 (UCSC)IL18BP  -     chr11:71998912-72002528 +  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL18BP  -     11q13.4   [Description]    (hg19-Feb_2009)
EnsemblIL18BP - 11q13.4 [CytoView hg19]  IL18BP - 11q13.4 [CytoView hg38]
Mapping of homologs : NCBIIL18BP [Mapview hg19]  IL18BP [Mapview hg38]
OMIM604113   
Gene and transcription
Genbank (Entrez)AB019504 AF086560 AF110799 AF110800 AF110801
RefSeq transcript (Entrez)NM_001039659 NM_001039660 NM_001145055 NM_001145057 NM_005699 NM_173042 NM_173043 NM_173044
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL18BP
Cluster EST : UnigeneHs.591967 [ NCBI ]
CGAP (NCI)Hs.591967
Alternative Splicing GalleryENSG00000137496
Gene ExpressionIL18BP [ NCBI-GEO ]   IL18BP [ EBI - ARRAY_EXPRESS ]   IL18BP [ SEEK ]   IL18BP [ MEM ]
Gene Expression Viewer (FireBrowse)IL18BP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10068
GTEX Portal (Tissue expression)IL18BP
Human Protein AtlasENSG00000137496-IL18BP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95998   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95998  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95998
Splice isoforms : SwissVarO95998
PhosPhoSitePlusO95998
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)IL18BP
DMDM Disease mutations10068
Blocks (Seattle)IL18BP
SuperfamilyO95998
Human Protein Atlas [tissue]ENSG00000137496-IL18BP [tissue]
Peptide AtlasO95998
HPRD04984
IPIIPI00873924   IPI00304305   IPI00848010   IPI00980560   
Protein Interaction databases
DIP (DOE-UCLA)O95998
IntAct (EBI)O95998
FunCoupENSG00000137496
BioGRIDIL18BP
STRING (EMBL)IL18BP
ZODIACIL18BP
Ontologies - Pathways
QuickGOO95998
Ontology : AmiGOextracellular region  extracellular space  response to lipopolysaccharide  interleukin-18 binding  T-helper 1 type immune response  receptor antagonist activity  extracellular exosome  cellular response to hydrogen peroxide  cellular response to tumor necrosis factor  extracellular negative regulation of signal transduction  
Ontology : EGO-EBIextracellular region  extracellular space  response to lipopolysaccharide  interleukin-18 binding  T-helper 1 type immune response  receptor antagonist activity  extracellular exosome  cellular response to hydrogen peroxide  cellular response to tumor necrosis factor  extracellular negative regulation of signal transduction  
NDEx NetworkIL18BP
Atlas of Cancer Signalling NetworkIL18BP
Wikipedia pathwaysIL18BP
Orthology - Evolution
OrthoDB10068
GeneTree (enSembl)ENSG00000137496
Phylogenetic Trees/Animal Genes : TreeFamIL18BP
HOVERGENO95998
HOGENOMO95998
Homologs : HomoloGeneIL18BP
Homology/Alignments : Family Browser (UCSC)IL18BP
Gene fusions - Rearrangements
Tumor Fusion PortalIL18BP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL18BP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL18BP
dbVarIL18BP
ClinVarIL18BP
1000_GenomesIL18BP 
Exome Variant ServerIL18BP
ExAC (Exome Aggregation Consortium)ENSG00000137496
GNOMAD BrowserENSG00000137496
Genetic variants : HAPMAP10068
Genomic Variants (DGV)IL18BP [DGVbeta]
DECIPHERIL18BP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL18BP 
Mutations
ICGC Data PortalIL18BP 
TCGA Data PortalIL18BP 
Broad Tumor PortalIL18BP
OASIS PortalIL18BP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL18BP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL18BP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL18BP
DgiDB (Drug Gene Interaction Database)IL18BP
DoCM (Curated mutations)IL18BP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL18BP (select a term)
intoGenIL18BP
Cancer3DIL18BP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604113   
Orphanet
DisGeNETIL18BP
MedgenIL18BP
Genetic Testing Registry IL18BP
NextProtO95998 [Medical]
TSGene10068
GENETestsIL18BP
Target ValidationIL18BP
Huge Navigator IL18BP [HugePedia]
snp3D : Map Gene to Disease10068
BioCentury BCIQIL18BP
ClinGenIL18BP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10068
Chemical/Pharm GKB GenePA29803
Clinical trialIL18BP
Miscellaneous
canSAR (ICR)IL18BP (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL18BP
EVEXIL18BP
GoPubMedIL18BP
iHOPIL18BP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:17:39 CET 2017

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