Atlas of Genetics and Cytogenetics in Oncology and Haematology

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IL19 (interleukin 19)

Identity

Alias_symbol (synonym)IL-19
MDA1
ZMDA1
IL-10C
NG.1
Other alias
HGNC (Hugo) IL19
LocusID (NCBI) 29949
Atlas_Id 50642
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 206798870 and ends at 206842981 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IL19   5990
Cards
Entrez_Gene (NCBI)IL19  29949  interleukin 19
AliasesIL-10C; MDA1; NG.1; ZMDA1
GeneCards (Weizmann)IL19
Ensembl hg19 (Hinxton)ENSG00000142224 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142224 [Gene_View]  ENSG00000142224 [Sequence]  chr1:206798870-206842981 [Contig_View]  IL19 [Vega]
ICGC DataPortalENSG00000142224
TCGA cBioPortalIL19
AceView (NCBI)IL19
Genatlas (Paris)IL19
WikiGenes29949
SOURCE (Princeton)IL19
Genetics Home Reference (NIH)IL19
Genomic and cartography
GoldenPath hg38 (UCSC)IL19  -     chr1:206798870-206842981 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL19  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblIL19 - 1q32.1 [CytoView hg19]  IL19 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIIL19 [Mapview hg19]  IL19 [Mapview hg38]
OMIM605687   
Gene and transcription
Genbank (Entrez)AF192498 AF453946 AY040367 CA306526 FJ380053
RefSeq transcript (Entrez)NM_013371 NM_153758
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL19
Cluster EST : UnigeneHs.661017 [ NCBI ]
CGAP (NCI)Hs.661017
Alternative Splicing GalleryENSG00000142224
Gene ExpressionIL19 [ NCBI-GEO ]   IL19 [ EBI - ARRAY_EXPRESS ]   IL19 [ SEEK ]   IL19 [ MEM ]
Gene Expression Viewer (FireBrowse)IL19 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29949
GTEX Portal (Tissue expression)IL19
Human Protein AtlasENSG00000142224-IL19 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UHD0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UHD0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UHD0
Splice isoforms : SwissVarQ9UHD0
PhosPhoSitePlusQ9UHD0
Domaine pattern : Prosite (Expaxy)INTERLEUKIN_10 (PS00520)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    IL-10/19/20/22/24/26_fam    IL-10_CS    IL-19   
Domain families : Pfam (Sanger)IL10 (PF00726)   
Domain families : Pfam (NCBI)pfam00726   
Conserved Domain (NCBI)IL19
DMDM Disease mutations29949
Blocks (Seattle)IL19
PDB (SRS)1N1F   
PDB (PDBSum)1N1F   
PDB (IMB)1N1F   
PDB (RSDB)1N1F   
Structural Biology KnowledgeBase1N1F   
SCOP (Structural Classification of Proteins)1N1F   
CATH (Classification of proteins structures)1N1F   
SuperfamilyQ9UHD0
Human Protein Atlas [tissue]ENSG00000142224-IL19 [tissue]
Peptide AtlasQ9UHD0
HPRD05747
IPIIPI00028480   IPI00376786   
Protein Interaction databases
DIP (DOE-UCLA)Q9UHD0
IntAct (EBI)Q9UHD0
FunCoupENSG00000142224
BioGRIDIL19
STRING (EMBL)IL19
ZODIACIL19
Ontologies - Pathways
QuickGOQ9UHD0
Ontology : AmiGOcytokine activity  extracellular region  extracellular region  extracellular space  apoptotic process  immune response  signal transduction  regulation of signaling receptor activity  negative regulation of low-density lipoprotein particle clearance  cytokine-mediated signaling pathway  interleukin-6 biosynthetic process  reactive oxygen species metabolic process  negative regulation of extrinsic apoptotic signaling pathway  positive regulation of intrinsic apoptotic signaling pathway  
Ontology : EGO-EBIcytokine activity  extracellular region  extracellular region  extracellular space  apoptotic process  immune response  signal transduction  regulation of signaling receptor activity  negative regulation of low-density lipoprotein particle clearance  cytokine-mediated signaling pathway  interleukin-6 biosynthetic process  reactive oxygen species metabolic process  negative regulation of extrinsic apoptotic signaling pathway  positive regulation of intrinsic apoptotic signaling pathway  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway   
NDEx NetworkIL19
Atlas of Cancer Signalling NetworkIL19
Wikipedia pathwaysIL19
Orthology - Evolution
OrthoDB29949
GeneTree (enSembl)ENSG00000142224
Phylogenetic Trees/Animal Genes : TreeFamIL19
HOVERGENQ9UHD0
HOGENOMQ9UHD0
Homologs : HomoloGeneIL19
Homology/Alignments : Family Browser (UCSC)IL19
Gene fusions - Rearrangements
Fusion : QuiverIL19
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL19 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL19
dbVarIL19
ClinVarIL19
1000_GenomesIL19 
Exome Variant ServerIL19
ExAC (Exome Aggregation Consortium)ENSG00000142224
GNOMAD BrowserENSG00000142224
Varsome BrowserIL19
Genetic variants : HAPMAP29949
Genomic Variants (DGV)IL19 [DGVbeta]
DECIPHERIL19 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL19 
Mutations
ICGC Data PortalIL19 
TCGA Data PortalIL19 
Broad Tumor PortalIL19
OASIS PortalIL19 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL19  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL19
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL19
DgiDB (Drug Gene Interaction Database)IL19
DoCM (Curated mutations)IL19 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL19 (select a term)
intoGenIL19
Cancer3DIL19(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605687   
Orphanet
DisGeNETIL19
MedgenIL19
Genetic Testing Registry IL19
NextProtQ9UHD0 [Medical]
TSGene29949
GENETestsIL19
Target ValidationIL19
Huge Navigator IL19 [HugePedia]
snp3D : Map Gene to Disease29949
BioCentury BCIQIL19
ClinGenIL19
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29949
Chemical/Pharm GKB GenePA29806
Clinical trialIL19
Miscellaneous
canSAR (ICR)IL19 (select the gene name)
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL19
EVEXIL19
GoPubMedIL19
iHOPIL19
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:13:13 CET 2018
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