Atlas of Genetics and Cytogenetics in Oncology and Haematology

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IL1RL1 (interleukin 1 receptor like 1)

Identity

Alias (NCBI)DER4
FIT-1
IL33R
ST2
ST2L
ST2V
T1
HGNC (Hugo) IL1RL1
HGNC Alias symbST2
FIT-1
ST2L
ST2V
DER4
T1
IL33R
HGNC Alias namehomolog of mouse growth stimulation-expressed
LocusID (NCBI) 9173
Atlas_Id 46331
Location 2q12.1  [Link to chromosome band 2q12]
Location_base_pair Starts at 102311563 and ends at 102352037 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IL1RL1   5998
Cards
Entrez_Gene (NCBI)IL1RL1    interleukin 1 receptor like 1
AliasesDER4; FIT-1; IL33R; ST2; 
ST2L; ST2V; T1
GeneCards (Weizmann)IL1RL1
Ensembl hg19 (Hinxton)ENSG00000115602 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115602 [Gene_View]  ENSG00000115602 [Sequence]  chr2:102311563-102352037 [Contig_View]  IL1RL1 [Vega]
ICGC DataPortalENSG00000115602
TCGA cBioPortalIL1RL1
AceView (NCBI)IL1RL1
Genatlas (Paris)IL1RL1
SOURCE (Princeton)IL1RL1
Genetics Home Reference (NIH)IL1RL1
Genomic and cartography
GoldenPath hg38 (UCSC)IL1RL1  -     chr2:102311563-102352037 +  2q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL1RL1  -     2q12.1   [Description]    (hg19-Feb_2009)
GoldenPathIL1RL1 - 2q12.1 [CytoView hg19]  IL1RL1 - 2q12.1 [CytoView hg38]
ImmunoBaseENSG00000115602
genome Data Viewer NCBIIL1RL1 [Mapview hg19]  
OMIM601203   
Gene and transcription
Genbank (Entrez)AB012701 AB029084 AK291578 AK303389 AL117622
RefSeq transcript (Entrez)NM_001282408 NM_003856 NM_016232 NM_173459
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL1RL1
Alternative Splicing GalleryENSG00000115602
Gene ExpressionIL1RL1 [ NCBI-GEO ]   IL1RL1 [ EBI - ARRAY_EXPRESS ]   IL1RL1 [ SEEK ]   IL1RL1 [ MEM ]
Gene Expression Viewer (FireBrowse)IL1RL1 [ Firebrowse - Broad ]
GenevisibleExpression of IL1RL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9173
GTEX Portal (Tissue expression)IL1RL1
Human Protein AtlasENSG00000115602-IL1RL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01638   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ01638  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ01638
Splice isoforms : SwissVarQ01638
PhosPhoSitePlusQ01638
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    TIR (PS50104)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    IL-1_rcpt_fam    IL-1_rcpt_I/II-typ    TIR_dom    Toll_tir_struct_dom_sf   
Domain families : Pfam (Sanger)I-set (PF07679)    TIR (PF01582)   
Domain families : Pfam (NCBI)pfam07679    pfam01582   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  TIR (SM00255)  
Conserved Domain (NCBI)IL1RL1
Blocks (Seattle)IL1RL1
PDB (RSDB)4KC3   
PDB Europe4KC3   
PDB (PDBSum)4KC3   
PDB (IMB)4KC3   
Structural Biology KnowledgeBase4KC3   
SCOP (Structural Classification of Proteins)4KC3   
CATH (Classification of proteins structures)4KC3   
SuperfamilyQ01638
Human Protein Atlas [tissue]ENSG00000115602-IL1RL1 [tissue]
Peptide AtlasQ01638
HPRD03123
IPIIPI00296161   IPI00218676   IPI00296164   IPI00917734   IPI00916616   
Protein Interaction databases
DIP (DOE-UCLA)Q01638
IntAct (EBI)Q01638
BioGRIDIL1RL1
STRING (EMBL)IL1RL1
ZODIACIL1RL1
Ontologies - Pathways
QuickGOQ01638
Ontology : AmiGOinterleukin-33 binding  interleukin-33 receptor activity  negative regulation of T-helper 1 type immune response  cytokine receptor activity  interleukin-1 receptor activity  protein binding  extracellular region  cytosol  plasma membrane  plasma membrane  focal adhesion  immune response  signal transduction  external side of plasma membrane  integral component of membrane  negative regulation of interferon-gamma production  positive regulation of interleukin-5 production  interleukin-33-mediated signaling pathway  positive regulation of macrophage activation  NAD(P)+ nucleosidase activity  positive regulation of inflammatory response  NAD+ nucleotidase, cyclic ADP-ribose generating  positive regulation of chemokine secretion  
Ontology : EGO-EBIinterleukin-33 binding  interleukin-33 receptor activity  negative regulation of T-helper 1 type immune response  cytokine receptor activity  interleukin-1 receptor activity  protein binding  extracellular region  cytosol  plasma membrane  plasma membrane  focal adhesion  immune response  signal transduction  external side of plasma membrane  integral component of membrane  negative regulation of interferon-gamma production  positive regulation of interleukin-5 production  interleukin-33-mediated signaling pathway  positive regulation of macrophage activation  NAD(P)+ nucleosidase activity  positive regulation of inflammatory response  NAD+ nucleotidase, cyclic ADP-ribose generating  positive regulation of chemokine secretion  
NDEx NetworkIL1RL1
Atlas of Cancer Signalling NetworkIL1RL1
Wikipedia pathwaysIL1RL1
Orthology - Evolution
OrthoDB9173
GeneTree (enSembl)ENSG00000115602
Phylogenetic Trees/Animal Genes : TreeFamIL1RL1
HOGENOMQ01638
Homologs : HomoloGeneIL1RL1
Homology/Alignments : Family Browser (UCSC)IL1RL1
Gene fusions - Rearrangements
Fusion : QuiverIL1RL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL1RL1 [hg38]
dbVarIL1RL1
ClinVarIL1RL1
MonarchIL1RL1
1000_GenomesIL1RL1 
Exome Variant ServerIL1RL1
GNOMAD BrowserENSG00000115602
Varsome BrowserIL1RL1
Genomic Variants (DGV)IL1RL1 [DGVbeta]
DECIPHERIL1RL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL1RL1 
Mutations
ICGC Data PortalIL1RL1 
TCGA Data PortalIL1RL1 
Broad Tumor PortalIL1RL1
OASIS PortalIL1RL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL1RL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIL1RL1
Mutations and Diseases : HGMDIL1RL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL1RL1
DgiDB (Drug Gene Interaction Database)IL1RL1
DoCM (Curated mutations)IL1RL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL1RL1 (select a term)
intoGenIL1RL1
Cancer3DIL1RL1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601203   
Orphanet
DisGeNETIL1RL1
MedgenIL1RL1
Genetic Testing Registry IL1RL1
NextProtQ01638 [Medical]
GENETestsIL1RL1
Target ValidationIL1RL1
Huge Navigator IL1RL1 [HugePedia]
ClinGenIL1RL1
Clinical trials, drugs, therapy
MyCancerGenomeIL1RL1
Protein Interactions : CTD
Pharm GKB GenePA29814
PharosQ01638
Clinical trialIL1RL1
Miscellaneous
canSAR (ICR)IL1RL1 (select the gene name)
HarmonizomeIL1RL1
DataMed IndexIL1RL1
Probes
Litterature
PubMed240 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIL1RL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:20:09 CET 2021
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