Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IL1RL1 (interleukin 1 receptor like 1)

Identity

Alias_symbol (synonym)ST2
FIT-1
ST2L
ST2V
DER4
T1
IL33R
Other alias
HGNC (Hugo) IL1RL1
LocusID (NCBI) 9173
Atlas_Id 46331
Location 2q12.1  [Link to chromosome band 2q12]
Location_base_pair Starts at 102311502 and ends at 102346100 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL1RL1   5998
Cards
Entrez_Gene (NCBI)IL1RL1  9173  interleukin 1 receptor like 1
AliasesDER4; FIT-1; IL33R; ST2; 
ST2L; ST2V; T1
GeneCards (Weizmann)IL1RL1
Ensembl hg19 (Hinxton)ENSG00000115602 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115602 [Gene_View]  chr2:102311502-102346100 [Contig_View]  IL1RL1 [Vega]
ICGC DataPortalENSG00000115602
TCGA cBioPortalIL1RL1
AceView (NCBI)IL1RL1
Genatlas (Paris)IL1RL1
WikiGenes9173
SOURCE (Princeton)IL1RL1
Genetics Home Reference (NIH)IL1RL1
Genomic and cartography
GoldenPath hg38 (UCSC)IL1RL1  -     chr2:102311502-102346100 +  2q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL1RL1  -     2q12.1   [Description]    (hg19-Feb_2009)
EnsemblIL1RL1 - 2q12.1 [CytoView hg19]  IL1RL1 - 2q12.1 [CytoView hg38]
Mapping of homologs : NCBIIL1RL1 [Mapview hg19]  IL1RL1 [Mapview hg38]
OMIM601203   
Gene and transcription
Genbank (Entrez)AB012701 AB029084 AK291578 AK303389 AL117622
RefSeq transcript (Entrez)NM_001282408 NM_003856 NM_016232 NM_173459
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL1RL1
Cluster EST : UnigeneHs.731651 [ NCBI ]
CGAP (NCI)Hs.731651
Alternative Splicing GalleryENSG00000115602
Gene ExpressionIL1RL1 [ NCBI-GEO ]   IL1RL1 [ EBI - ARRAY_EXPRESS ]   IL1RL1 [ SEEK ]   IL1RL1 [ MEM ]
Gene Expression Viewer (FireBrowse)IL1RL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9173
GTEX Portal (Tissue expression)IL1RL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01638   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ01638  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ01638
Splice isoforms : SwissVarQ01638
PhosPhoSitePlusQ01638
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    TIR (PS50104)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    IL-1_rcpt_fam    IL-1_rcpt_I/II-typ    TIR_dom   
Domain families : Pfam (Sanger)I-set (PF07679)    TIR (PF01582)   
Domain families : Pfam (NCBI)pfam07679    pfam01582   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  TIR (SM00255)  
Conserved Domain (NCBI)IL1RL1
DMDM Disease mutations9173
Blocks (Seattle)IL1RL1
PDB (SRS)4KC3   
PDB (PDBSum)4KC3   
PDB (IMB)4KC3   
PDB (RSDB)4KC3   
Structural Biology KnowledgeBase4KC3   
SCOP (Structural Classification of Proteins)4KC3   
CATH (Classification of proteins structures)4KC3   
SuperfamilyQ01638
Human Protein AtlasENSG00000115602
Peptide AtlasQ01638
HPRD03123
IPIIPI00296161   IPI00218676   IPI00296164   IPI00917734   IPI00916616   
Protein Interaction databases
DIP (DOE-UCLA)Q01638
IntAct (EBI)Q01638
FunCoupENSG00000115602
BioGRIDIL1RL1
STRING (EMBL)IL1RL1
ZODIACIL1RL1
Ontologies - Pathways
QuickGOQ01638
Ontology : AmiGOinterleukin-33 binding  interleukin-33 receptor activity  negative regulation of T-helper 1 type immune response  cytokine receptor activity  interleukin-1 receptor activity  signal transducer activity, downstream of receptor  protein binding  proteinaceous extracellular matrix  plasma membrane  immune response  signal transduction  external side of plasma membrane  integral component of membrane  negative regulation of interferon-gamma production  positive regulation of interleukin-5 production  interleukin-33-mediated signaling pathway  positive regulation of macrophage activation  negative regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of inflammatory response  positive regulation of chemokine secretion  
Ontology : EGO-EBIinterleukin-33 binding  interleukin-33 receptor activity  negative regulation of T-helper 1 type immune response  cytokine receptor activity  interleukin-1 receptor activity  signal transducer activity, downstream of receptor  protein binding  proteinaceous extracellular matrix  plasma membrane  immune response  signal transduction  external side of plasma membrane  integral component of membrane  negative regulation of interferon-gamma production  positive regulation of interleukin-5 production  interleukin-33-mediated signaling pathway  positive regulation of macrophage activation  negative regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of inflammatory response  positive regulation of chemokine secretion  
NDEx NetworkIL1RL1
Atlas of Cancer Signalling NetworkIL1RL1
Wikipedia pathwaysIL1RL1
Orthology - Evolution
OrthoDB9173
GeneTree (enSembl)ENSG00000115602
Phylogenetic Trees/Animal Genes : TreeFamIL1RL1
HOVERGENQ01638
HOGENOMQ01638
Homologs : HomoloGeneIL1RL1
Homology/Alignments : Family Browser (UCSC)IL1RL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL1RL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL1RL1
dbVarIL1RL1
ClinVarIL1RL1
1000_GenomesIL1RL1 
Exome Variant ServerIL1RL1
ExAC (Exome Aggregation Consortium)IL1RL1 (select the gene name)
Genetic variants : HAPMAP9173
Genomic Variants (DGV)IL1RL1 [DGVbeta]
DECIPHERIL1RL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL1RL1 
Mutations
ICGC Data PortalIL1RL1 
TCGA Data PortalIL1RL1 
Broad Tumor PortalIL1RL1
OASIS PortalIL1RL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL1RL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL1RL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL1RL1
DgiDB (Drug Gene Interaction Database)IL1RL1
DoCM (Curated mutations)IL1RL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL1RL1 (select a term)
intoGenIL1RL1
Cancer3DIL1RL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601203   
Orphanet
MedgenIL1RL1
Genetic Testing Registry IL1RL1
NextProtQ01638 [Medical]
TSGene9173
GENETestsIL1RL1
Target ValidationIL1RL1
Huge Navigator IL1RL1 [HugePedia]
snp3D : Map Gene to Disease9173
BioCentury BCIQIL1RL1
ClinGenIL1RL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9173
Chemical/Pharm GKB GenePA29814
Clinical trialIL1RL1
Miscellaneous
canSAR (ICR)IL1RL1 (select the gene name)
Probes
Litterature
PubMed194 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL1ZL1/TD>
EVEXIL1RL1
GoPubMedIL1RL1
iHOPIL1RL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:56:17 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.