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IL1RL2 (interleukin 1 receptor like 2)

Identity

Alias (NCBI)IL-1Rrp2
IL-36R
IL1R-rp2
IL1RRP2
HGNC (Hugo) IL1RL2
HGNC Alias symbIL1R-rp2
IL1RRP2
LocusID (NCBI) 8808
Atlas_Id 64594
Location 2q12.1  [Link to chromosome band 2q12]
Location_base_pair Starts at 102187023 and ends at 102240001 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IL1RL2 (2q12.1) / IL1R2 (2q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)IL1RL2   5999
Cards
Entrez_Gene (NCBI)IL1RL2    interleukin 1 receptor like 2
AliasesIL-1Rrp2; IL-36R; IL1R-rp2; IL1RRP2
GeneCards (Weizmann)IL1RL2
Ensembl hg19 (Hinxton)ENSG00000115598 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115598 [Gene_View]  ENSG00000115598 [Sequence]  chr2:102187023-102240001 [Contig_View]  IL1RL2 [Vega]
ICGC DataPortalENSG00000115598
TCGA cBioPortalIL1RL2
AceView (NCBI)IL1RL2
Genatlas (Paris)IL1RL2
SOURCE (Princeton)IL1RL2
Genetics Home Reference (NIH)IL1RL2
Genomic and cartography
GoldenPath hg38 (UCSC)IL1RL2  -     chr2:102187023-102240001 +  2q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL1RL2  -     2q12.1   [Description]    (hg19-Feb_2009)
GoldenPathIL1RL2 - 2q12.1 [CytoView hg19]  IL1RL2 - 2q12.1 [CytoView hg38]
ImmunoBaseENSG00000115598
Genome Data Viewer NCBIIL1RL2 [Mapview hg19]  
OMIM604512   
Gene and transcription
Genbank (Entrez)AF284434 AK315334 BC107064 CA448166 U49065
RefSeq transcript (Entrez)NM_001351446 NM_001351447 NM_001351448 NM_001351449 NM_001351450 NM_003854
Consensus coding sequences : CCDS (NCBI)IL1RL2
Gene ExpressionIL1RL2 [ NCBI-GEO ]   IL1RL2 [ EBI - ARRAY_EXPRESS ]   IL1RL2 [ SEEK ]   IL1RL2 [ MEM ]
Gene Expression Viewer (FireBrowse)IL1RL2 [ Firebrowse - Broad ]
GenevisibleExpression of IL1RL2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8808
GTEX Portal (Tissue expression)IL1RL2
Human Protein AtlasENSG00000115598-IL1RL2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HB29   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HB29  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HB29
PhosPhoSitePlusQ9HB29
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    TIR (PS50104)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    IL-1_rcpt_fam    IL-1_rcpt_I-typ    IL-1_rcpt_I/II-typ    IL-1RAcP-like_ig    TIR_dom    Toll_tir_struct_dom_sf   
Domain families : Pfam (Sanger)Ig_2 (PF13895)    Ig_6 (PF18452)    TIR (PF01582)   
Domain families : Pfam (NCBI)pfam13895    pfam18452    pfam01582   
Domain families : Smart (EMBL)IG (SM00409)  TIR (SM00255)  
Conserved Domain (NCBI)IL1RL2
PDB (RSDB)6U6U   
PDB Europe6U6U   
PDB (PDBSum)6U6U   
PDB (IMB)6U6U   
Structural Biology KnowledgeBase6U6U   
SCOP (Structural Classification of Proteins)6U6U   
CATH (Classification of proteins structures)6U6U   
SuperfamilyQ9HB29
AlphaFold pdb e-kbQ9HB29   
Human Protein Atlas [tissue]ENSG00000115598-IL1RL2 [tissue]
HPRD05150
Protein Interaction databases
DIP (DOE-UCLA)Q9HB29
IntAct (EBI)Q9HB29
BioGRIDIL1RL2
STRING (EMBL)IL1RL2
ZODIACIL1RL2
Ontologies - Pathways
QuickGOQ9HB29
Ontology : AmiGOinterleukin-1 receptor activity  interleukin-1, type I, activating receptor activity  plasma membrane  integral component of plasma membrane  inflammatory response  cellular defense response  signal transduction  cytokine-mediated signaling pathway  positive regulation of interleukin-6 production  innate immune response  positive regulation of T cell differentiation  NAD(P)+ nucleosidase activity  regulation of inflammatory response  NAD+ nucleotidase, cyclic ADP-ribose generating  interleukin-1-mediated signaling pathway  cellular response to cytokine stimulus  
Ontology : EGO-EBIinterleukin-1 receptor activity  interleukin-1, type I, activating receptor activity  plasma membrane  integral component of plasma membrane  inflammatory response  cellular defense response  signal transduction  cytokine-mediated signaling pathway  positive regulation of interleukin-6 production  innate immune response  positive regulation of T cell differentiation  NAD(P)+ nucleosidase activity  regulation of inflammatory response  NAD+ nucleotidase, cyclic ADP-ribose generating  interleukin-1-mediated signaling pathway  cellular response to cytokine stimulus  
NDEx NetworkIL1RL2
Atlas of Cancer Signalling NetworkIL1RL2
Wikipedia pathwaysIL1RL2
Orthology - Evolution
OrthoDB8808
GeneTree (enSembl)ENSG00000115598
Phylogenetic Trees/Animal Genes : TreeFamIL1RL2
Homologs : HomoloGeneIL1RL2
Homology/Alignments : Family Browser (UCSC)IL1RL2
Gene fusions - Rearrangements
Fusion : QuiverIL1RL2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL1RL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL1RL2
dbVarIL1RL2
ClinVarIL1RL2
MonarchIL1RL2
1000_GenomesIL1RL2 
Exome Variant ServerIL1RL2
GNOMAD BrowserENSG00000115598
Varsome BrowserIL1RL2
ACMGIL1RL2 variants
VarityQ9HB29
Genomic Variants (DGV)IL1RL2 [DGVbeta]
DECIPHERIL1RL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL1RL2 
Mutations
ICGC Data PortalIL1RL2 
TCGA Data PortalIL1RL2 
Broad Tumor PortalIL1RL2
OASIS PortalIL1RL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL1RL2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIL1RL2
Mutations and Diseases : HGMDIL1RL2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaIL1RL2
DgiDB (Drug Gene Interaction Database)IL1RL2
DoCM (Curated mutations)IL1RL2
CIViC (Clinical Interpretations of Variants in Cancer)IL1RL2
Cancer3DIL1RL2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604512   
Orphanet
DisGeNETIL1RL2
MedgenIL1RL2
Genetic Testing Registry IL1RL2
NextProtQ9HB29 [Medical]
GENETestsIL1RL2
Target ValidationIL1RL2
Huge Navigator IL1RL2 [HugePedia]
ClinGenIL1RL2
Clinical trials, drugs, therapy
MyCancerGenomeIL1RL2
Protein Interactions : CTDIL1RL2
Pharm GKB GenePA29815
PharosQ9HB29
Clinical trialIL1RL2
Miscellaneous
canSAR (ICR)IL1RL2
HarmonizomeIL1RL2
DataMed IndexIL1RL2
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIL1RL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:53:42 CEST 2021

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