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IL20 (interleukin 20)

Identity

Alias (NCBI)IL-20
IL10D
ZCYTO10
HGNC (Hugo) IL20
HGNC Alias symbZCYTO10
IL10D
IL-20
LocusID (NCBI) 50604
Atlas_Id 46098
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 206865809 and ends at 206869223 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IL20   6002
Cards
Entrez_Gene (NCBI)IL20    interleukin 20
AliasesIL-20; IL10D; ZCYTO10
GeneCards (Weizmann)IL20
Ensembl hg19 (Hinxton)ENSG00000162891 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162891 [Gene_View]  ENSG00000162891 [Sequence]  chr1:206865809-206869223 [Contig_View]  IL20 [Vega]
ICGC DataPortalENSG00000162891
TCGA cBioPortalIL20
AceView (NCBI)IL20
Genatlas (Paris)IL20
SOURCE (Princeton)IL20
Genetics Home Reference (NIH)IL20
Genomic and cartography
GoldenPath hg38 (UCSC)IL20  -     chr1:206865809-206869223 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL20  -     1q32.1   [Description]    (hg19-Feb_2009)
GoldenPathIL20 - 1q32.1 [CytoView hg19]  IL20 - 1q32.1 [CytoView hg38]
ImmunoBaseENSG00000162891
genome Data Viewer NCBIIL20 [Mapview hg19]  
OMIM605619   
Gene and transcription
Genbank (Entrez)AF224266 AY358320 AY876922 BC069311 BC069364
RefSeq transcript (Entrez)NM_018724
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL20
Alternative Splicing GalleryENSG00000162891
Gene ExpressionIL20 [ NCBI-GEO ]   IL20 [ EBI - ARRAY_EXPRESS ]   IL20 [ SEEK ]   IL20 [ MEM ]
Gene Expression Viewer (FireBrowse)IL20 [ Firebrowse - Broad ]
GenevisibleExpression of IL20 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50604
GTEX Portal (Tissue expression)IL20
Human Protein AtlasENSG00000162891-IL20 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYY1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYY1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYY1
Splice isoforms : SwissVarQ9NYY1
PhosPhoSitePlusQ9NYY1
Domaine pattern : Prosite (Expaxy)INTERLEUKIN_10 (PS00520)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    IL-10/19/20/22/24/26_fam    IL-10_CS    IL-20   
Domain families : Pfam (Sanger)IL10 (PF00726)   
Domain families : Pfam (NCBI)pfam00726   
Domain families : Smart (EMBL)IL10 (SM00188)  
Conserved Domain (NCBI)IL20
Blocks (Seattle)IL20
PDB (RSDB)4DOH   
PDB Europe4DOH   
PDB (PDBSum)4DOH   
PDB (IMB)4DOH   
Structural Biology KnowledgeBase4DOH   
SCOP (Structural Classification of Proteins)4DOH   
CATH (Classification of proteins structures)4DOH   
SuperfamilyQ9NYY1
Human Protein Atlas [tissue]ENSG00000162891-IL20 [tissue]
Peptide AtlasQ9NYY1
HPRD05728
IPIIPI00000048   IPI00719795   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYY1
IntAct (EBI)Q9NYY1
BioGRIDIL20
STRING (EMBL)IL20
ZODIACIL20
Ontologies - Pathways
QuickGOQ9NYY1
Ontology : AmiGOcytokine activity  extracellular region  extracellular space  cytokine-mediated signaling pathway  positive regulation of tyrosine phosphorylation of STAT protein  interleukin-20 receptor binding  interleukin-22 receptor binding  positive regulation of epidermal cell differentiation  positive regulation of keratinocyte differentiation  positive regulation of osteoclast differentiation  regulation of inflammatory response  
Ontology : EGO-EBIcytokine activity  extracellular region  extracellular space  cytokine-mediated signaling pathway  positive regulation of tyrosine phosphorylation of STAT protein  interleukin-20 receptor binding  interleukin-22 receptor binding  positive regulation of epidermal cell differentiation  positive regulation of keratinocyte differentiation  positive regulation of osteoclast differentiation  regulation of inflammatory response  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway   
NDEx NetworkIL20
Atlas of Cancer Signalling NetworkIL20
Wikipedia pathwaysIL20
Orthology - Evolution
OrthoDB50604
GeneTree (enSembl)ENSG00000162891
Phylogenetic Trees/Animal Genes : TreeFamIL20
HOGENOMQ9NYY1
Homologs : HomoloGeneIL20
Homology/Alignments : Family Browser (UCSC)IL20
Gene fusions - Rearrangements
Fusion : QuiverIL20
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL20 [hg38]
dbVarIL20
ClinVarIL20
MonarchIL20
1000_GenomesIL20 
Exome Variant ServerIL20
GNOMAD BrowserENSG00000162891
Varsome BrowserIL20
Genomic Variants (DGV)IL20 [DGVbeta]
DECIPHERIL20 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL20 
Mutations
ICGC Data PortalIL20 
TCGA Data PortalIL20 
Broad Tumor PortalIL20
OASIS PortalIL20 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL20  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIL20
Mutations and Diseases : HGMDIL20
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL20
DgiDB (Drug Gene Interaction Database)IL20
DoCM (Curated mutations)IL20 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL20 (select a term)
intoGenIL20
Cancer3DIL20(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605619   
Orphanet
DisGeNETIL20
MedgenIL20
Genetic Testing Registry IL20
NextProtQ9NYY1 [Medical]
GENETestsIL20
Target ValidationIL20
Huge Navigator IL20 [HugePedia]
ClinGenIL20
Clinical trials, drugs, therapy
MyCancerGenomeIL20
Protein Interactions : CTD
Pharm GKB GenePA29817
PharosQ9NYY1
Clinical trialIL20
Miscellaneous
canSAR (ICR)IL20 (select the gene name)
HarmonizomeIL20
DataMed IndexIL20
Probes
Litterature
PubMed72 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIL20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 1 18:20:09 CET 2021
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