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IL22RA2 (interleukin 22 receptor subunit alpha 2)

Identity

Alias_namesinterleukin 22 receptor, alpha 2
Alias_symbol (synonym)CRF2-S1
IL-22BP
Other aliasCRF2-10
CRF2X
IL-22R-alpha-2
IL-22RA2
ZCYTOR16
HGNC (Hugo) IL22RA2
LocusID (NCBI) 116379
Atlas_Id 64597
Location 6q23.3  [Link to chromosome band 6q23]
Location_base_pair Starts at 137143820 and ends at 137173648 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCDC28A (6q24.1) / IL22RA2 (6q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL22RA2   14901
Cards
Entrez_Gene (NCBI)IL22RA2  116379  interleukin 22 receptor subunit alpha 2
AliasesCRF2-10; CRF2-S1; CRF2X; IL-22BP; 
IL-22R-alpha-2; IL-22RA2; ZCYTOR16
GeneCards (Weizmann)IL22RA2
Ensembl hg19 (Hinxton)ENSG00000164485 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164485 [Gene_View]  ENSG00000164485 [Sequence]  chr6:137143820-137173648 [Contig_View]  IL22RA2 [Vega]
ICGC DataPortalENSG00000164485
TCGA cBioPortalIL22RA2
AceView (NCBI)IL22RA2
Genatlas (Paris)IL22RA2
WikiGenes116379
SOURCE (Princeton)IL22RA2
Genetics Home Reference (NIH)IL22RA2
Genomic and cartography
GoldenPath hg38 (UCSC)IL22RA2  -     chr6:137143820-137173648 -  6q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL22RA2  -     6q23.3   [Description]    (hg19-Feb_2009)
EnsemblIL22RA2 - 6q23.3 [CytoView hg19]  IL22RA2 - 6q23.3 [CytoView hg38]
Mapping of homologs : NCBIIL22RA2 [Mapview hg19]  IL22RA2 [Mapview hg38]
OMIM606648   
Gene and transcription
Genbank (Entrez)AI824338 AJ297262 AJ313161 AJ313162 AY040566
RefSeq transcript (Entrez)NM_052962 NM_181309 NM_181310
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL22RA2
Cluster EST : UnigeneHs.126891 [ NCBI ]
CGAP (NCI)Hs.126891
Alternative Splicing GalleryENSG00000164485
Gene ExpressionIL22RA2 [ NCBI-GEO ]   IL22RA2 [ EBI - ARRAY_EXPRESS ]   IL22RA2 [ SEEK ]   IL22RA2 [ MEM ]
Gene Expression Viewer (FireBrowse)IL22RA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116379
GTEX Portal (Tissue expression)IL22RA2
Human Protein AtlasENSG00000164485-IL22RA2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969J5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969J5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969J5
Splice isoforms : SwissVarQ969J5
PhosPhoSitePlusQ969J5
Domains : Interpro (EBI)FN3_dom    Ig-like_fold    Interferon/interleukin_rcp_dom   
Domain families : Pfam (Sanger)Interfer-bind (PF09294)    Tissue_fac (PF01108)   
Domain families : Pfam (NCBI)pfam09294    pfam01108   
Conserved Domain (NCBI)IL22RA2
DMDM Disease mutations116379
Blocks (Seattle)IL22RA2
PDB (SRS)3G9V   
PDB (PDBSum)3G9V   
PDB (IMB)3G9V   
PDB (RSDB)3G9V   
Structural Biology KnowledgeBase3G9V   
SCOP (Structural Classification of Proteins)3G9V   
CATH (Classification of proteins structures)3G9V   
SuperfamilyQ969J5
Human Protein Atlas [tissue]ENSG00000164485-IL22RA2 [tissue]
Peptide AtlasQ969J5
HPRD05973
IPIIPI00056389   IPI00059236   IPI00178012   
Protein Interaction databases
DIP (DOE-UCLA)Q969J5
IntAct (EBI)Q969J5
FunCoupENSG00000164485
BioGRIDIL22RA2
STRING (EMBL)IL22RA2
ZODIACIL22RA2
Ontologies - Pathways
QuickGOQ969J5
Ontology : AmiGOextracellular region  extracellular space  cytosol  plasma membrane  integral component of membrane  cytokine-mediated signaling pathway  interleukin-22 binding  interleukin-22 receptor activity  negative regulation of inflammatory response  
Ontology : EGO-EBIextracellular region  extracellular space  cytosol  plasma membrane  integral component of membrane  cytokine-mediated signaling pathway  interleukin-22 binding  interleukin-22 receptor activity  negative regulation of inflammatory response  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway   
NDEx NetworkIL22RA2
Atlas of Cancer Signalling NetworkIL22RA2
Wikipedia pathwaysIL22RA2
Orthology - Evolution
OrthoDB116379
GeneTree (enSembl)ENSG00000164485
Phylogenetic Trees/Animal Genes : TreeFamIL22RA2
HOVERGENQ969J5
HOGENOMQ969J5
Homologs : HomoloGeneIL22RA2
Homology/Alignments : Family Browser (UCSC)IL22RA2
Gene fusions - Rearrangements
Fusion : QuiverIL22RA2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL22RA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL22RA2
dbVarIL22RA2
ClinVarIL22RA2
1000_GenomesIL22RA2 
Exome Variant ServerIL22RA2
ExAC (Exome Aggregation Consortium)ENSG00000164485
GNOMAD BrowserENSG00000164485
Varsome BrowserIL22RA2
Genetic variants : HAPMAP116379
Genomic Variants (DGV)IL22RA2 [DGVbeta]
DECIPHERIL22RA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL22RA2 
Mutations
ICGC Data PortalIL22RA2 
TCGA Data PortalIL22RA2 
Broad Tumor PortalIL22RA2
OASIS PortalIL22RA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL22RA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL22RA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL22RA2
DgiDB (Drug Gene Interaction Database)IL22RA2
DoCM (Curated mutations)IL22RA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL22RA2 (select a term)
intoGenIL22RA2
Cancer3DIL22RA2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606648   
Orphanet
DisGeNETIL22RA2
MedgenIL22RA2
Genetic Testing Registry IL22RA2
NextProtQ969J5 [Medical]
TSGene116379
GENETestsIL22RA2
Target ValidationIL22RA2
Huge Navigator IL22RA2 [HugePedia]
snp3D : Map Gene to Disease116379
BioCentury BCIQIL22RA2
ClinGenIL22RA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116379
Chemical/Pharm GKB GenePA134983729
Clinical trialIL22RA2
Miscellaneous
canSAR (ICR)IL22RA2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL22RA2
EVEXIL22RA2
GoPubMedIL22RA2
iHOPIL22RA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Jul 30 13:49:55 CEST 2018

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