Atlas of Genetics and Cytogenetics in Oncology and Haematology

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IL24 (interleukin 24)

Identity

Alias_namesST16
Alias_symbol (synonym)mda-7
IL10B
Mob-5
C49A
FISP
IL-24
Other aliasMDA7
MOB5
HGNC (Hugo) IL24
LocusID (NCBI) 11009
Atlas_Id 40956
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 206897443 and ends at 206904139 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IL24   11346
Cards
Entrez_Gene (NCBI)IL24  11009  interleukin 24
AliasesC49A; FISP; IL10B; MDA7; 
MOB5; ST16
GeneCards (Weizmann)IL24
Ensembl hg19 (Hinxton)ENSG00000162892 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162892 [Gene_View]  ENSG00000162892 [Sequence]  chr1:206897443-206904139 [Contig_View]  IL24 [Vega]
ICGC DataPortalENSG00000162892
TCGA cBioPortalIL24
AceView (NCBI)IL24
Genatlas (Paris)IL24
WikiGenes11009
SOURCE (Princeton)IL24
Genetics Home Reference (NIH)IL24
Genomic and cartography
GoldenPath hg38 (UCSC)IL24  -     chr1:206897443-206904139 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL24  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblIL24 - 1q32.1 [CytoView hg19]  IL24 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIIL24 [Mapview hg19]  IL24 [Mapview hg38]
OMIM604136   
Gene and transcription
Genbank (Entrez)AI521306 AW949784 AY237723 AY641440 AY641441
RefSeq transcript (Entrez)NM_001185156 NM_001185157 NM_001185158 NM_006850 NM_181339
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL24
Cluster EST : UnigeneHs.744273 [ NCBI ]
CGAP (NCI)Hs.744273
Alternative Splicing GalleryENSG00000162892
Gene ExpressionIL24 [ NCBI-GEO ]   IL24 [ EBI - ARRAY_EXPRESS ]   IL24 [ SEEK ]   IL24 [ MEM ]
Gene Expression Viewer (FireBrowse)IL24 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11009
GTEX Portal (Tissue expression)IL24
Human Protein AtlasENSG00000162892-IL24 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13007   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13007  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13007
Splice isoforms : SwissVarQ13007
PhosPhoSitePlusQ13007
Domaine pattern : Prosite (Expaxy)INTERLEUKIN_10 (PS00520)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    IL-10_CS    IL-24   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)IL24
DMDM Disease mutations11009
Blocks (Seattle)IL24
SuperfamilyQ13007
Human Protein Atlas [tissue]ENSG00000162892-IL24 [tissue]
Peptide AtlasQ13007
HPRD04995
IPIIPI00011399   IPI00479860   IPI00377240   IPI00658036   IPI00749199   
Protein Interaction databases
DIP (DOE-UCLA)Q13007
IntAct (EBI)Q13007
FunCoupENSG00000162892
BioGRIDIL24
STRING (EMBL)IL24
ZODIACIL24
Ontologies - Pathways
QuickGOQ13007
Ontology : AmiGOcytokine activity  protein binding  extracellular region  extracellular space  apoptotic process  positive regulation of cell proliferation  negative regulation of cell proliferation  regulation of receptor activity  cytokine-mediated signaling pathway  negative regulation of cell migration  wound healing  serine phosphorylation of STAT protein  positive regulation of tyrosine phosphorylation of STAT protein  cellular response to lipopolysaccharide  cellular response to interleukin-4  
Ontology : EGO-EBIcytokine activity  protein binding  extracellular region  extracellular space  apoptotic process  positive regulation of cell proliferation  negative regulation of cell proliferation  regulation of receptor activity  cytokine-mediated signaling pathway  negative regulation of cell migration  wound healing  serine phosphorylation of STAT protein  positive regulation of tyrosine phosphorylation of STAT protein  cellular response to lipopolysaccharide  cellular response to interleukin-4  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway   
NDEx NetworkIL24
Atlas of Cancer Signalling NetworkIL24
Wikipedia pathwaysIL24
Orthology - Evolution
OrthoDB11009
GeneTree (enSembl)ENSG00000162892
Phylogenetic Trees/Animal Genes : TreeFamIL24
HOVERGENQ13007
HOGENOMQ13007
Homologs : HomoloGeneIL24
Homology/Alignments : Family Browser (UCSC)IL24
Gene fusions - Rearrangements
Fusion : QuiverIL24
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL24 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL24
dbVarIL24
ClinVarIL24
1000_GenomesIL24 
Exome Variant ServerIL24
ExAC (Exome Aggregation Consortium)ENSG00000162892
GNOMAD BrowserENSG00000162892
Genetic variants : HAPMAP11009
Genomic Variants (DGV)IL24 [DGVbeta]
DECIPHERIL24 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL24 
Mutations
ICGC Data PortalIL24 
TCGA Data PortalIL24 
Broad Tumor PortalIL24
OASIS PortalIL24 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL24  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL24
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL24
DgiDB (Drug Gene Interaction Database)IL24
DoCM (Curated mutations)IL24 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL24 (select a term)
intoGenIL24
Cancer3DIL24(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604136   
Orphanet
DisGeNETIL24
MedgenIL24
Genetic Testing Registry IL24
NextProtQ13007 [Medical]
TSGene11009
GENETestsIL24
Target ValidationIL24
Huge Navigator IL24 [HugePedia]
snp3D : Map Gene to Disease11009
BioCentury BCIQIL24
ClinGenIL24
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11009
Chemical/Pharm GKB GenePA29825
Clinical trialIL24
Miscellaneous
canSAR (ICR)IL24 (select the gene name)
Probes
Litterature
PubMed138 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL24
EVEXIL24
GoPubMedIL24
iHOPIL24
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:30:47 CEST 2018
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