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IL26 (interleukin 26)

Identity

Alias_symbol (synonym)AK155
IL-26
Other alias
HGNC (Hugo) IL26
LocusID (NCBI) 55801
Atlas_Id 53680
Location 12q15  [Link to chromosome band 12q15]
Location_base_pair Starts at 68201349 and ends at 68225791 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PPM1H (12q14.1) / IL26 (12q15)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(12;12)(q14;q15) PPM1H/IL26


External links

Nomenclature
HGNC (Hugo)IL26   17119
Cards
Entrez_Gene (NCBI)IL26  55801  interleukin 26
AliasesAK155; IL-26
GeneCards (Weizmann)IL26
Ensembl hg19 (Hinxton)ENSG00000111536 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111536 [Gene_View]  ENSG00000111536 [Sequence]  chr12:68201349-68225791 [Contig_View]  IL26 [Vega]
ICGC DataPortalENSG00000111536
TCGA cBioPortalIL26
AceView (NCBI)IL26
Genatlas (Paris)IL26
WikiGenes55801
SOURCE (Princeton)IL26
Genetics Home Reference (NIH)IL26
Genomic and cartography
GoldenPath hg38 (UCSC)IL26  -     chr12:68201349-68225791 -  12q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL26  -     12q15   [Description]    (hg19-Feb_2009)
EnsemblIL26 - 12q15 [CytoView hg19]  IL26 - 12q15 [CytoView hg38]
Mapping of homologs : NCBIIL26 [Mapview hg19]  IL26 [Mapview hg38]
OMIM605679   
Gene and transcription
Genbank (Entrez)AJ251549 BC066270 BC066271
RefSeq transcript (Entrez)NM_018402
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL26
Cluster EST : UnigeneHs.272350 [ NCBI ]
CGAP (NCI)Hs.272350
Alternative Splicing GalleryENSG00000111536
Gene ExpressionIL26 [ NCBI-GEO ]   IL26 [ EBI - ARRAY_EXPRESS ]   IL26 [ SEEK ]   IL26 [ MEM ]
Gene Expression Viewer (FireBrowse)IL26 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55801
GTEX Portal (Tissue expression)IL26
Human Protein AtlasENSG00000111536-IL26 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NPH9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NPH9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NPH9
Splice isoforms : SwissVarQ9NPH9
PhosPhoSitePlusQ9NPH9
Domaine pattern : Prosite (Expaxy)INTERLEUKIN_10 (PS00520)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    IL-10/19/20/22/24/26_fam    IL-10_CS   
Domain families : Pfam (Sanger)IL10 (PF00726)   
Domain families : Pfam (NCBI)pfam00726   
Conserved Domain (NCBI)IL26
DMDM Disease mutations55801
Blocks (Seattle)IL26
SuperfamilyQ9NPH9
Human Protein Atlas [tissue]ENSG00000111536-IL26 [tissue]
Peptide AtlasQ9NPH9
HPRD16140
IPIIPI00020088   
Protein Interaction databases
DIP (DOE-UCLA)Q9NPH9
IntAct (EBI)Q9NPH9
FunCoupENSG00000111536
BioGRIDIL26
STRING (EMBL)IL26
ZODIACIL26
Ontologies - Pathways
QuickGOQ9NPH9
Ontology : AmiGOcytokine activity  extracellular region  extracellular space  cytosol  cell-cell signaling  regulation of signaling receptor activity  cytokine-mediated signaling pathway  positive regulation of stress-activated MAPK cascade  positive regulation of transcription by RNA polymerase II  positive regulation of JAK-STAT cascade  negative regulation of epithelial cell proliferation  positive regulation of cytokine secretion  positive regulation of protein kinase B signaling  positive regulation of ERK1 and ERK2 cascade  
Ontology : EGO-EBIcytokine activity  extracellular region  extracellular space  cytosol  cell-cell signaling  regulation of signaling receptor activity  cytokine-mediated signaling pathway  positive regulation of stress-activated MAPK cascade  positive regulation of transcription by RNA polymerase II  positive regulation of JAK-STAT cascade  negative regulation of epithelial cell proliferation  positive regulation of cytokine secretion  positive regulation of protein kinase B signaling  positive regulation of ERK1 and ERK2 cascade  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway   
NDEx NetworkIL26
Atlas of Cancer Signalling NetworkIL26
Wikipedia pathwaysIL26
Orthology - Evolution
OrthoDB55801
GeneTree (enSembl)ENSG00000111536
Phylogenetic Trees/Animal Genes : TreeFamIL26
HOVERGENQ9NPH9
HOGENOMQ9NPH9
Homologs : HomoloGeneIL26
Homology/Alignments : Family Browser (UCSC)IL26
Gene fusions - Rearrangements
Fusion : MitelmanPPM1H/IL26 [12q14.1/12q15]  [t(12;12)(q14;q15)]  
Fusion : QuiverIL26
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL26 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL26
dbVarIL26
ClinVarIL26
1000_GenomesIL26 
Exome Variant ServerIL26
ExAC (Exome Aggregation Consortium)ENSG00000111536
GNOMAD BrowserENSG00000111536
Varsome BrowserIL26
Genetic variants : HAPMAP55801
Genomic Variants (DGV)IL26 [DGVbeta]
DECIPHERIL26 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL26 
Mutations
ICGC Data PortalIL26 
TCGA Data PortalIL26 
Broad Tumor PortalIL26
OASIS PortalIL26 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL26  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL26
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL26
DgiDB (Drug Gene Interaction Database)IL26
DoCM (Curated mutations)IL26 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL26 (select a term)
intoGenIL26
Cancer3DIL26(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605679   
Orphanet
DisGeNETIL26
MedgenIL26
Genetic Testing Registry IL26
NextProtQ9NPH9 [Medical]
TSGene55801
GENETestsIL26
Target ValidationIL26
Huge Navigator IL26 [HugePedia]
snp3D : Map Gene to Disease55801
BioCentury BCIQIL26
ClinGenIL26
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55801
Chemical/Pharm GKB GenePA29826
Clinical trialIL26
Miscellaneous
canSAR (ICR)IL26 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL26
EVEXIL26
GoPubMedIL26
iHOPIL26
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:13:18 CET 2018

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