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IL27 (interleukin 27)

Identity

Alias_namesIL30
interleukin 30
Alias_symbol (synonym)IL-27
p28
IL27p28
IL-27A
IL27A
MGC71873
Other alias
HGNC (Hugo) IL27
LocusID (NCBI) 246778
Atlas_Id 46464
Location 16p12.1  [Link to chromosome band 16p12]
Location_base_pair Starts at 28499362 and ends at 28506834 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL27   19157
Cards
Entrez_Gene (NCBI)IL27  246778  interleukin 27
AliasesIL-27; IL-27A; IL27A; IL27p28; 
IL30; p28
GeneCards (Weizmann)IL27
Ensembl hg19 (Hinxton)ENSG00000197272 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197272 [Gene_View]  chr16:28499362-28506834 [Contig_View]  IL27 [Vega]
ICGC DataPortalENSG00000197272
TCGA cBioPortalIL27
AceView (NCBI)IL27
Genatlas (Paris)IL27
WikiGenes246778
SOURCE (Princeton)IL27
Genetics Home Reference (NIH)IL27
Genomic and cartography
GoldenPath hg38 (UCSC)IL27  -     chr16:28499362-28506834 -  16p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL27  -     16p12.1   [Description]    (hg19-Feb_2009)
EnsemblIL27 - 16p12.1 [CytoView hg19]  IL27 - 16p12.1 [CytoView hg38]
Mapping of homologs : NCBIIL27 [Mapview hg19]  IL27 [Mapview hg38]
OMIM608273   
Gene and transcription
Genbank (Entrez)AY099296 BC062422 HQ447563
RefSeq transcript (Entrez)NM_145659
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL27
Cluster EST : UnigeneHs.528111 [ NCBI ]
CGAP (NCI)Hs.528111
Alternative Splicing GalleryENSG00000197272
Gene ExpressionIL27 [ NCBI-GEO ]   IL27 [ EBI - ARRAY_EXPRESS ]   IL27 [ SEEK ]   IL27 [ MEM ]
Gene Expression Viewer (FireBrowse)IL27 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)246778
GTEX Portal (Tissue expression)IL27
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NEV9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NEV9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NEV9
Splice isoforms : SwissVarQ8NEV9
PhosPhoSitePlusQ8NEV9
Domains : Interpro (EBI)IL-27_alpha   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)IL27
DMDM Disease mutations246778
Blocks (Seattle)IL27
SuperfamilyQ8NEV9
Human Protein AtlasENSG00000197272
Peptide AtlasQ8NEV9
HPRD16307
IPIIPI00302598   
Protein Interaction databases
DIP (DOE-UCLA)Q8NEV9
IntAct (EBI)Q8NEV9
FunCoupENSG00000197272
BioGRIDIL27
STRING (EMBL)IL27
ZODIACIL27
Ontologies - Pathways
QuickGOQ8NEV9
Ontology : AmiGOpositive regulation of defense response to virus by host  receptor binding  cytokine activity  extracellular region  extracellular space  extracellular space  inflammatory response  response to bacterium  regulation of T cell proliferation  regulation of T cell proliferation  positive regulation of interferon-gamma biosynthetic process  innate immune response  interleukin-27 receptor binding  interleukin-27 receptor binding  regulation of T-helper 1 cell differentiation  
Ontology : EGO-EBIpositive regulation of defense response to virus by host  receptor binding  cytokine activity  extracellular region  extracellular space  extracellular space  inflammatory response  response to bacterium  regulation of T cell proliferation  regulation of T cell proliferation  positive regulation of interferon-gamma biosynthetic process  innate immune response  interleukin-27 receptor binding  interleukin-27 receptor binding  regulation of T-helper 1 cell differentiation  
NDEx NetworkIL27
Atlas of Cancer Signalling NetworkIL27
Wikipedia pathwaysIL27
Orthology - Evolution
OrthoDB246778
GeneTree (enSembl)ENSG00000197272
Phylogenetic Trees/Animal Genes : TreeFamIL27
HOVERGENQ8NEV9
HOGENOMQ8NEV9
Homologs : HomoloGeneIL27
Homology/Alignments : Family Browser (UCSC)IL27
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL27 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL27
dbVarIL27
ClinVarIL27
1000_GenomesIL27 
Exome Variant ServerIL27
ExAC (Exome Aggregation Consortium)IL27 (select the gene name)
Genetic variants : HAPMAP246778
Genomic Variants (DGV)IL27 [DGVbeta]
DECIPHERIL27 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL27 
Mutations
ICGC Data PortalIL27 
TCGA Data PortalIL27 
Broad Tumor PortalIL27
OASIS PortalIL27 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL27  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL27
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL27
DgiDB (Drug Gene Interaction Database)IL27
DoCM (Curated mutations)IL27 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL27 (select a term)
intoGenIL27
Cancer3DIL27(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608273   
Orphanet
MedgenIL27
Genetic Testing Registry IL27
NextProtQ8NEV9 [Medical]
TSGene246778
GENETestsIL27
Target ValidationIL27
Huge Navigator IL27 [HugePedia]
snp3D : Map Gene to Disease246778
BioCentury BCIQIL27
ClinGenIL27
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD246778
Chemical/Pharm GKB GenePA134870478
Clinical trialIL27
Miscellaneous
canSAR (ICR)IL27 (select the gene name)
Probes
Litterature
PubMed181 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL27
EVEXIL27
GoPubMedIL27
iHOPIL27
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:56:18 CEST 2017

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