Atlas of Genetics and Cytogenetics in Oncology and Haematology


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IL2RB (interleukin 2 receptor, beta)

Identity

Other namesCD122
IL15RB
P70-75
HGNC (Hugo) IL2RB
LocusID (NCBI) 3560
Location 22q12.3
Location_base_pair Starts at 37521880 and ends at 37545962 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IL2RB   6009
Cards
Entrez_Gene (NCBI)IL2RB  3560  interleukin 2 receptor, beta
GeneCards (Weizmann)IL2RB
Ensembl (Hinxton)ENSG00000100385 [Gene_View]  chr22:37521880-37545962 [Contig_View]  IL2RB [Vega]
ICGC DataPortalENSG00000100385
AceView (NCBI)IL2RB
Genatlas (Paris)IL2RB
WikiGenes3560
SOURCE (Princeton)NM_000878
Genomic and cartography
GoldenPath (UCSC)IL2RB  -  22q12.3   chr22:37521880-37545962 -  22q12.3   [Description]    (hg19-Feb_2009)
EnsemblIL2RB - 22q12.3 [CytoView]
Mapping of homologs : NCBIIL2RB [Mapview]
OMIM146710   
Gene and transcription
Genbank (Entrez)AA834613 AK312860 AW193701 BC025691 CR456506
RefSeq transcript (Entrez)NM_000878
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004929430
Consensus coding sequences : CCDS (NCBI)IL2RB
Cluster EST : UnigeneHs.474787 [ NCBI ]
CGAP (NCI)Hs.474787
Alternative Splicing : Fast-db (Paris)GSHG0020369
Alternative Splicing GalleryENSG00000100385
Gene ExpressionIL2RB [ NCBI-GEO ]     IL2RB [ SEEK ]   IL2RB [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP14784 (Uniprot)
NextProtP14784  [Medical]
With graphics : InterProP14784
Splice isoforms : SwissVarP14784 (Swissvar)
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    HEMATOPO_REC_S_F1 (PS01355)   
Domains : Interpro (EBI)Fibronectin_type3    Hempt_rcpt_S_F1_CS    Ig-like_fold   
Related proteins : CluSTrP14784
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)FN3 (SM00060)  
DMDM Disease mutations3560
Blocks (Seattle)P14784
PDB (SRS)1ILM    1ILN    2B5I    2ERJ    3QAZ    4GS7   
PDB (PDBSum)1ILM    1ILN    2B5I    2ERJ    3QAZ    4GS7   
PDB (IMB)1ILM    1ILN    2B5I    2ERJ    3QAZ    4GS7   
PDB (RSDB)1ILM    1ILN    2B5I    2ERJ    3QAZ    4GS7   
Human Protein AtlasENSG00000100385
Peptide AtlasP14784
HPRD00896
IPIIPI00878728   IPI00878405   IPI00878276   IPI00878426   IPI00878872   IPI00916279   
Protein Interaction databases
DIP (DOE-UCLA)P14784
IntAct (EBI)P14784
FunCoupENSG00000100385
BioGRIDIL2RB
IntegromeDBIL2RB
STRING (EMBL)IL2RB
Ontologies - Pathways
QuickGOP14784
Ontology : AmiGOinterleukin-2 receptor activity  interleukin-2 receptor activity  plasma membrane  integral component of plasma membrane  protein complex assembly  signal transduction  external side of plasma membrane  membrane  viral process  cytokine-mediated signaling pathway  interleukin-2 binding  interleukin-2-mediated signaling pathway  interleukin-2-mediated signaling pathway  negative regulation of apoptotic process  
Ontology : EGO-EBIinterleukin-2 receptor activity  interleukin-2 receptor activity  plasma membrane  integral component of plasma membrane  protein complex assembly  signal transduction  external side of plasma membrane  membrane  viral process  cytokine-mediated signaling pathway  interleukin-2 binding  interleukin-2-mediated signaling pathway  interleukin-2-mediated signaling pathway  negative regulation of apoptotic process  
Pathways : BIOCARTAIL 2 signaling pathway [Genes]    IL-2 Receptor Beta Chain in T cell Activation [Genes]   
Pathways : KEGGCytokine-cytokine receptor interaction    Endocytosis    PI3K-Akt signaling pathway    Jak-STAT signaling pathway    Measles    HTLV-I infection    Transcriptional misregulation in cancer   
Protein Interaction DatabaseIL2RB
Wikipedia pathwaysIL2RB
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)IL2RB
SNP (GeneSNP Utah)IL2RB
SNP : HGBaseIL2RB
Genetic variants : HAPMAPIL2RB
1000_GenomesIL2RB 
ICGC programENSG00000100385 
CONAN: Copy Number AnalysisIL2RB 
Somatic Mutations in Cancer : COSMICIL2RB 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)22:37521880-37545962
Mutations and Diseases : HGMDIL2RB
OMIM146710   
MedgenIL2RB
GENETestsIL2RB
Disease Genetic AssociationIL2RB
Huge Navigator IL2RB [HugePedia]  IL2RB [HugeCancerGEM]
Genomic VariantsIL2RB  IL2RB [DGVbeta]
Exome VariantIL2RB
dbVarIL2RB
ClinVarIL2RB
snp3D : Map Gene to Disease3560
General knowledge
Homologs : HomoloGeneIL2RB
Homology/Alignments : Family Browser (UCSC)IL2RB
Phylogenetic Trees/Animal Genes : TreeFamIL2RB
Chemical/Protein Interactions : CTD3560
Chemical/Pharm GKB GenePA29829
Clinical trialIL2RB
Cancer Resource (Charite)ENSG00000100385
Other databases
Probes
Litterature
PubMed129 Pubmed reference(s) in Entrez
CoreMineIL2RB
GoPubMedIL2RB
iHOPIL2RB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:33:56 CET 2014

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