Atlas of Genetics and Cytogenetics in Oncology and Haematology

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IL2RB (interleukin 2 receptor, beta)

Identity

Other namesCD122
IL15RB
P70-75
HGNC (Hugo) IL2RB
LocusID (NCBI) 3560
Location 22q12.3
Location_base_pair Starts at 37521880 and ends at 37545962 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IL2RB   6009
Entrez_Gene (NCBI)IL2RB  3560  interleukin 2 receptor, beta
Cards
GeneCards (Weizmann)IL2RB
Ensembl (Hinxton)ENSG00000100385 [Gene_View]  chr22:37521880-37545962 [Contig_View]  IL2RB [Vega]
AceView (NCBI)IL2RB
Genatlas (Paris)IL2RB
SOURCE (Stanford)NM_000878
Genomic and cartography
GoldenPath (UCSC)IL2RB  -  22q12.3   chr22:37521880-37545962 -  22q12.3   [Description]    (hg19-Feb_2009)
EnsemblIL2RB - 22q12.3 [CytoView]
Mapping of homologs : NCBIIL2RB [Mapview]
OMIM146710   
Gene and transcription
Genbank (Entrez)AA834613 AK312860 AW193701 BC025691 CR456506
RefSeq transcript (SRS)NM_000878
RefSeq transcript (Entrez)NM_000878
RefSeq genomic (SRS)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004078112
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004078112
Consensus coding sequences : CCDS (NCBI)IL2RB
Cluster EST : UnigeneHs.474787 [ SRS ] Hs.474787 [ NCBI ]
CGAP (NCI)Hs.474787
Alternative Splicing : Fast-db (Paris)GSHG0020369
Alternative Splicing GalleryENSG00000100385
Gene ExpressionIL2RB [ NCBI-GEO ]   IL2RB [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP14784 (SRS) P14784 (Uniprot)
NextProtP14784
With graphics : InterProP14784
Splice isoforms : SwissVarP14784(Swissvar)
Domaine pattern : Prosite (SRS)FN3 (PS50853)    HEMATOPO_REC_S_F1 (PS01355)   
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    HEMATOPO_REC_S_F1 (PS01355)   
Domains : Interpro (SRS)Fibronectin_type3    Hempt_rcpt_S_F1_CS    Ig-like_fold   
Domains : Interpro (EBI)Fibronectin_type3    Hempt_rcpt_S_F1_CS    Ig-like_fold   
Related proteins : CluSTrP14784
Domain families : Pfam (SRS)
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)FN3 (SM00060)  
DMDM3560
Blocks (Seattle)P14784
PDB (SRS)1ILM    1ILN    2B5I    2ERJ    3QAZ   
PDB (PDBSum)1ILM    1ILN    2B5I    2ERJ    3QAZ   
PDB (IMB)1ILM    1ILN    2B5I    2ERJ    3QAZ   
PDB (RSDB)1ILM    1ILN    2B5I    2ERJ    3QAZ   
Human Protein AtlasENSG00000100385
HPRD00896
IPIIPI00878728   IPI00878405   IPI00878276   IPI00878426   IPI00878872   IPI00916279   
Protein Interaction databases
DIP (DOE-UCLA)P14784
IntAct (EBI)P14784
FunCoupENSG00000100385
REACTOMEIL2RB
Protein Interaction Database3560
BioGRIDIL2RB
InParanoidP14784
Interologous Interaction database P14784
IntegromeDBIL2RB
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)IL2RB
SNP (GeneSNP Utah)IL2RB
SNP : HGBaseIL2RB
Genetic variants : HAPMAPIL2RB
Somatic Mutations in Cancer : COSMICIL2RB 
CONAN: Copy Number AnalysisIL2RB 
Mutations and Diseases : HGMDIL2RB
OMIM146710   
GENETests146710   
Disease Genetic AssociationIL2RB
Huge Navigator IL2RB [HugePedia]  IL2RB [HugeCancerGEM]
Genomic VariantsIL2RB  IL2RB [DGVbeta]
snp3D : Map Gene to Disease3560
General knowledge
Homologs : HomoloGeneIL2RB
Homology/Alignments : Family Browser (UCSC)IL2RB
Phylogenetic Trees/Animal Genes : TreeFamIL2RB
Chemical/Protein Interactions : CTD3560
Chemical/Pharm GKB GenePA29829
Clinical trialIL2RB
Cancer Resource (Charite)ENSG00000100385
Ontology : AmiGOinterleukin-2 receptor activity  interleukin-2 receptor activity  plasma membrane  integral to plasma membrane  protein complex assembly  signal transduction  external side of plasma membrane  virus-host interaction  cytokine-mediated signaling pathway  interleukin-2 binding  interleukin-2-mediated signaling pathway  interleukin-2-mediated signaling pathway  negative regulation of apoptotic process  
Ontology : EGO-EBIinterleukin-2 receptor activity  interleukin-2 receptor activity  plasma membrane  integral to plasma membrane  protein complex assembly  signal transduction  external side of plasma membrane  virus-host interaction  cytokine-mediated signaling pathway  interleukin-2 binding  interleukin-2-mediated signaling pathway  interleukin-2-mediated signaling pathway  negative regulation of apoptotic process  
Pathways : BIOCARTAIL 2 signaling pathway [Genes]    IL-2 Receptor Beta Chain in T cell Activation [Genes]   
Pathways : KEGGCytokine-cytokine receptor interactionJak-STAT signaling pathway
Other databases
Probes
Litterature
PubMed119 Pubmed reference(s) in Entrez
PubGeneIL2RB
iHOPIL2RB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:45:53 CEST 2013
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