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IL31RA (interleukin 31 receptor A)

Identity

Alias_symbol (synonym)CRL3
GLM-R
CRL
Glmr
IL-31RA
Other aliasGLMR
GPL
PLCA2
PRO21384
hGLM-R
HGNC (Hugo) IL31RA
LocusID (NCBI) 133396
Atlas_Id 45692
Location 5q11.2  [Link to chromosome band 5q11]
Location_base_pair Starts at 55851379 and ends at 55917337 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IL31RA (5q11.2) / KRCC1 (2p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL31RA   18969
Cards
Entrez_Gene (NCBI)IL31RA  133396  interleukin 31 receptor A
AliasesCRL; CRL3; GLM-R; GLMR; 
GPL; IL-31RA; PLCA2; PRO21384; hGLM-R
GeneCards (Weizmann)IL31RA
Ensembl hg19 (Hinxton)ENSG00000164509 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164509 [Gene_View]  ENSG00000164509 [Sequence]  chr5:55851379-55917337 [Contig_View]  IL31RA [Vega]
ICGC DataPortalENSG00000164509
TCGA cBioPortalIL31RA
AceView (NCBI)IL31RA
Genatlas (Paris)IL31RA
WikiGenes133396
SOURCE (Princeton)IL31RA
Genetics Home Reference (NIH)IL31RA
Genomic and cartography
GoldenPath hg38 (UCSC)IL31RA  -     chr5:55851379-55917337 +  5q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL31RA  -     5q11.2   [Description]    (hg19-Feb_2009)
GoldenPathIL31RA - 5q11.2 [CytoView hg19]  IL31RA - 5q11.2 [CytoView hg38]
ImmunoBaseENSG00000164509
Mapping of homologs : NCBIIL31RA [Mapview hg19]  IL31RA [Mapview hg38]
OMIM609510   613955   
Gene and transcription
Genbank (Entrez)AF106913 AF486620 AK297938 AY358117 AY358740
RefSeq transcript (Entrez)NM_001242636 NM_001242637 NM_001242638 NM_001242639 NM_001297570 NM_001297572 NM_139017
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL31RA
Cluster EST : UnigeneHs.55378 [ NCBI ]
CGAP (NCI)Hs.55378
Alternative Splicing GalleryENSG00000164509
Gene ExpressionIL31RA [ NCBI-GEO ]   IL31RA [ EBI - ARRAY_EXPRESS ]   IL31RA [ SEEK ]   IL31RA [ MEM ]
Gene Expression Viewer (FireBrowse)IL31RA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)133396
GTEX Portal (Tissue expression)IL31RA
Human Protein AtlasENSG00000164509-IL31RA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NI17   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NI17  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NI17
Splice isoforms : SwissVarQ8NI17
PhosPhoSitePlusQ8NI17
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)   
Domains : Interpro (EBI)FN3_dom    FN3_sf    Ig-like_fold    TypeI_recpt_CBD   
Domain families : Pfam (Sanger)fn3 (PF00041)    IL6Ra-bind (PF09240)   
Domain families : Pfam (NCBI)pfam00041    pfam09240   
Domain families : Smart (EMBL)FN3 (SM00060)  
Conserved Domain (NCBI)IL31RA
DMDM Disease mutations133396
Blocks (Seattle)IL31RA
SuperfamilyQ8NI17
Human Protein Atlas [tissue]ENSG00000164509-IL31RA [tissue]
Peptide AtlasQ8NI17
HPRD17145
IPIIPI00478188   IPI00828127   IPI00828071   IPI00827821   IPI00465082   IPI00827666   IPI00827493   IPI00827904   IPI00827852   IPI00827997   IPI00827945   IPI00828090   
Protein Interaction databases
DIP (DOE-UCLA)Q8NI17
IntAct (EBI)Q8NI17
FunCoupENSG00000164509
BioGRIDIL31RA
STRING (EMBL)IL31RA
ZODIACIL31RA
Ontologies - Pathways
QuickGOQ8NI17
Ontology : AmiGOMAPK cascade  glandular epithelial cell differentiation  acute inflammatory response to antigenic stimulus  transcription coactivator activity  cytokine receptor activity  cytokine receptor activity  plasma membrane  defense response  transmembrane receptor protein tyrosine kinase signaling pathway  JAK-STAT cascade  positive regulation of cell proliferation  external side of plasma membrane  integral component of membrane  cytokine-mediated signaling pathway  protein kinase binding  cytokine binding  cytokine binding  cell junction  monocyte differentiation  macrophage differentiation  axon  T-helper 2 cell cytokine production  positive regulation of tyrosine phosphorylation of STAT protein  positive regulation of tyrosine phosphorylation of STAT protein  homeostatic process  presynaptic membrane  negative regulation of macrophage activation  negative regulation of apoptotic process  receptor complex  positive regulation of transcription, DNA-templated  defense response to other organism  
Ontology : EGO-EBIMAPK cascade  glandular epithelial cell differentiation  acute inflammatory response to antigenic stimulus  transcription coactivator activity  cytokine receptor activity  cytokine receptor activity  plasma membrane  defense response  transmembrane receptor protein tyrosine kinase signaling pathway  JAK-STAT cascade  positive regulation of cell proliferation  external side of plasma membrane  integral component of membrane  cytokine-mediated signaling pathway  protein kinase binding  cytokine binding  cytokine binding  cell junction  monocyte differentiation  macrophage differentiation  axon  T-helper 2 cell cytokine production  positive regulation of tyrosine phosphorylation of STAT protein  positive regulation of tyrosine phosphorylation of STAT protein  homeostatic process  presynaptic membrane  negative regulation of macrophage activation  negative regulation of apoptotic process  receptor complex  positive regulation of transcription, DNA-templated  defense response to other organism  
NDEx NetworkIL31RA
Atlas of Cancer Signalling NetworkIL31RA
Wikipedia pathwaysIL31RA
Orthology - Evolution
OrthoDB133396
GeneTree (enSembl)ENSG00000164509
Phylogenetic Trees/Animal Genes : TreeFamIL31RA
HOGENOMQ8NI17
Homologs : HomoloGeneIL31RA
Homology/Alignments : Family Browser (UCSC)IL31RA
Gene fusions - Rearrangements
Fusion : QuiverIL31RA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL31RA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL31RA
dbVarIL31RA
ClinVarIL31RA
1000_GenomesIL31RA 
Exome Variant ServerIL31RA
ExAC (Exome Aggregation Consortium)ENSG00000164509
GNOMAD BrowserENSG00000164509
Varsome BrowserIL31RA
Genetic variants : HAPMAP133396
Genomic Variants (DGV)IL31RA [DGVbeta]
DECIPHERIL31RA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL31RA 
Mutations
ICGC Data PortalIL31RA 
TCGA Data PortalIL31RA 
Broad Tumor PortalIL31RA
OASIS PortalIL31RA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL31RA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL31RA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL31RA
DgiDB (Drug Gene Interaction Database)IL31RA
DoCM (Curated mutations)IL31RA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL31RA (select a term)
intoGenIL31RA
Cancer3DIL31RA(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609510    613955   
Orphanet22120   
DisGeNETIL31RA
MedgenIL31RA
Genetic Testing Registry IL31RA
NextProtQ8NI17 [Medical]
TSGene133396
GENETestsIL31RA
Target ValidationIL31RA
Huge Navigator IL31RA [HugePedia]
snp3D : Map Gene to Disease133396
BioCentury BCIQIL31RA
ClinGenIL31RA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD133396
Chemical/Pharm GKB GenePA134952624
Clinical trialIL31RA
Miscellaneous
canSAR (ICR)IL31RA (select the gene name)
DataMed IndexIL31RA
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL31RA
EVEXIL31RA
GoPubMedIL31RA
iHOPIL31RA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri Jun 7 18:05:10 CEST 2019

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