Atlas of Genetics and Cytogenetics in Oncology and Haematology


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IL33 (interleukin 33)

Identity

Alias_namesC9orf26
chromosome 9 open reading frame 26 (NF-HEV)
Alias_symbol (synonym)DVS27
DKFZp586H0523
NF-HEV
IL1F11
Other aliasNFEHEV
HGNC (Hugo) IL33
LocusID (NCBI) 90865
Atlas_Id 50672
Location 9p24.1  [Link to chromosome band 9p24]
Location_base_pair Starts at 6215786 and ends at 6257983 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL33   16028
Cards
Entrez_Gene (NCBI)IL33  90865  interleukin 33
AliasesC9orf26; DVS27; IL1F11; NF-HEV; 
NFEHEV
GeneCards (Weizmann)IL33
Ensembl hg19 (Hinxton)ENSG00000137033 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137033 [Gene_View]  chr9:6215786-6257983 [Contig_View]  IL33 [Vega]
ICGC DataPortalENSG00000137033
TCGA cBioPortalIL33
AceView (NCBI)IL33
Genatlas (Paris)IL33
WikiGenes90865
SOURCE (Princeton)IL33
Genetics Home Reference (NIH)IL33
Genomic and cartography
GoldenPath hg38 (UCSC)IL33  -     chr9:6215786-6257983 +  9p24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL33  -     9p24.1   [Description]    (hg19-Feb_2009)
EnsemblIL33 - 9p24.1 [CytoView hg19]  IL33 - 9p24.1 [CytoView hg38]
Mapping of homologs : NCBIIL33 [Mapview hg19]  IL33 [Mapview hg38]
OMIM608678   
Gene and transcription
Genbank (Entrez)AB024518 AI610794 AK295908 AK303943 AK313414
RefSeq transcript (Entrez)NM_001199640 NM_001199641 NM_001314044 NM_001314045 NM_001314046 NM_001314047 NM_001314048 NM_033439
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL33
Cluster EST : UnigeneHs.731660 [ NCBI ]
CGAP (NCI)Hs.731660
Alternative Splicing GalleryENSG00000137033
Gene ExpressionIL33 [ NCBI-GEO ]   IL33 [ EBI - ARRAY_EXPRESS ]   IL33 [ SEEK ]   IL33 [ MEM ]
Gene Expression Viewer (FireBrowse)IL33 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90865
GTEX Portal (Tissue expression)IL33
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95760   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95760  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95760
Splice isoforms : SwissVarO95760
PhosPhoSitePlusO95760
Domains : Interpro (EBI)IL-33   
Domain families : Pfam (Sanger)IL33 (PF15095)   
Domain families : Pfam (NCBI)pfam15095   
Conserved Domain (NCBI)IL33
DMDM Disease mutations90865
Blocks (Seattle)IL33
PDB (SRS)2KLL    4KC3   
PDB (PDBSum)2KLL    4KC3   
PDB (IMB)2KLL    4KC3   
PDB (RSDB)2KLL    4KC3   
Structural Biology KnowledgeBase2KLL    4KC3   
SCOP (Structural Classification of Proteins)2KLL    4KC3   
CATH (Classification of proteins structures)2KLL    4KC3   
SuperfamilyO95760
Human Protein AtlasENSG00000137033
Peptide AtlasO95760
HPRD12275
IPIIPI00027628   IPI00908682   IPI00909430   
Protein Interaction databases
DIP (DOE-UCLA)O95760
IntAct (EBI)O95760
FunCoupENSG00000137033
BioGRIDIL33
STRING (EMBL)IL33
ZODIACIL33
Ontologies - Pathways
QuickGOO95760
Ontology : AmiGOmicroglial cell activation involved in immune response  negative regulation of leukocyte migration  negative regulation of T-helper 1 type immune response  positive regulation of type 2 immune response  cytokine activity  protein binding  extracellular region  extracellular space  nucleoplasm  nucleoplasm  chromosome  cytosol  transcription, DNA-templated  protein deubiquitination  transport vesicle  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  negative regulation of interferon-gamma production  positive regulation of interleukin-13 production  positive regulation of interleukin-4 production  positive regulation of interleukin-5 production  positive regulation of interleukin-6 production  type 2 immune response  positive regulation of macrophage activation  positive regulation of transcription from RNA polymerase II promoter  positive regulation of inflammatory response  positive regulation of inflammatory response  positive regulation of immunoglobulin secretion  negative regulation of immunoglobulin secretion  defense response to virus  microglial cell proliferation  positive regulation of chemokine secretion  extrinsic apoptotic signaling pathway  
Ontology : EGO-EBImicroglial cell activation involved in immune response  negative regulation of leukocyte migration  negative regulation of T-helper 1 type immune response  positive regulation of type 2 immune response  cytokine activity  protein binding  extracellular region  extracellular space  nucleoplasm  nucleoplasm  chromosome  cytosol  transcription, DNA-templated  protein deubiquitination  transport vesicle  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  negative regulation of interferon-gamma production  positive regulation of interleukin-13 production  positive regulation of interleukin-4 production  positive regulation of interleukin-5 production  positive regulation of interleukin-6 production  type 2 immune response  positive regulation of macrophage activation  positive regulation of transcription from RNA polymerase II promoter  positive regulation of inflammatory response  positive regulation of inflammatory response  positive regulation of immunoglobulin secretion  negative regulation of immunoglobulin secretion  defense response to virus  microglial cell proliferation  positive regulation of chemokine secretion&nBsp;&~bóp;extrinsic apoptotic signaling pathway  
Pathways : KEGGCytosolic DNA-sensing pathway    Influenza A   
NDEx NetworkIL33
Atlas of Cancer Signalling NetworkIL33
Wikipedia pathwaysIL33
Orthology - Evolution
OrthoDB90865
GeneTree (enSembl)ENSG00000137033
Phylogenetic Trees/Animal Genes : TreeFamIL33
HOVERGENO95760
HOGENOMO95760
Homologs : HomoloGeneIL33
Homology/Alignments : Family Browser (UCSC)IL33
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL33
dbVarIL33
ClinVarIL33
1000_GenomesIL33 
Exome Variant ServerIL33
ExAC (Exome Aggregation Consortium)IL33 (select the gene name)
Genetic variants : HAPMAP90865
Genomic Variants (DGV)IL33 [DGVbeta]
DECIPHERIL33 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL33 
Mutations
ICGC Data PortalIL33 
TCGA Data PortalIL33 
Broad Tumor PortalIL33
OASIS PortalIL33 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL33  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL33
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL33
DgiDB (Drug Gene Interaction Database)IL33
DoCM (Curated mutations)IL33 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL33 (select a term)
intoGenIL33
Cancer3DIL33(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608678   
Orphanet
MedgenIL33
Genetic Testing Registry IL33
NextProtO95760 [Medical]
TSGene90865
GENETestsIL33
Target ValidationIL33
Huge Navigator IL33 [HugePedia]
snp3D : Map Gene to Disease90865
BioCentury BCIQIL33
ClinGenIL33
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90865
Chemical/Pharm GKB GenePA162392005
Clinical trialIL33
Miscellaneous
canSAR (ICR)IL33 (select the gene name)
Probes
Litterature
PubMed314 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL33
EVEXIL33
GoPubMedIL33
iHOPIL33
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 25 19:13:13 CEST 2017

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