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IL36B (interleukin 36, beta)

Identity

Alias_namesIL1F8
interleukin 1 family, member 8 (eta)
Alias_symbol (synonym)FIL1
IL-1H2
IL-1F8
FILI-(ETA)
IL1-ETA
IL1H2
MGC126880
MGC126882
Other aliasFIL1-(ETA)
FIL1H
HGNC (Hugo) IL36B
LocusID (NCBI) 27177
Atlas_Id 64601
Location 2q13  [Link to chromosome band 2q13]
Location_base_pair Starts at 113779668 and ends at 113810444 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL36B   15564
Cards
Entrez_Gene (NCBI)IL36B  27177  interleukin 36, beta
AliasesFIL1; FIL1-(ETA); FIL1H; FILI-(ETA); 
IL-1F8; IL-1H2; IL1-ETA; IL1F8; IL1H2
GeneCards (Weizmann)IL36B
Ensembl hg19 (Hinxton)ENSG00000136696 [Gene_View]  chr2:113779668-113810444 [Contig_View]  IL36B [Vega]
Ensembl hg38 (Hinxton)ENSG00000136696 [Gene_View]  chr2:113779668-113810444 [Contig_View]  IL36B [Vega]
ICGC DataPortalENSG00000136696
TCGA cBioPortalIL36B
AceView (NCBI)IL36B
Genatlas (Paris)IL36B
WikiGenes27177
SOURCE (Princeton)IL36B
Genetics Home Reference (NIH)IL36B
Genomic and cartography
GoldenPath hg19 (UCSC)IL36B  -     chr2:113779668-113810444 -  2q13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)IL36B  -     2q13   [Description]    (hg38-Dec_2013)
EnsemblIL36B - 2q13 [CytoView hg19]  IL36B - 2q13 [CytoView hg38]
Mapping of homologs : NCBIIL36B [Mapview hg19]  IL36B [Mapview hg38]
OMIM605508   
Gene and transcription
Genbank (Entrez)AF200494 AF201833 BC101831 BC101833 CA441070
RefSeq transcript (Entrez)NM_014438 NM_173178
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929304
Consensus coding sequences : CCDS (NCBI)IL36B
Cluster EST : UnigeneHs.278909 [ NCBI ]
CGAP (NCI)Hs.278909
Alternative Splicing GalleryENSG00000136696
Gene ExpressionIL36B [ NCBI-GEO ]   IL36B [ EBI - ARRAY_EXPRESS ]   IL36B [ SEEK ]   IL36B [ MEM ]
Gene Expression Viewer (FireBrowse)IL36B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27177
GTEX Portal (Tissue expression)IL36B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZH7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZH7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZH7
Splice isoforms : SwissVarQ9NZH7
PhosPhoSitePlusQ9NZH7
Domains : Interpro (EBI)Cytokine_IL1-like    IL-36_beta   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)IL36B
DMDM Disease mutations27177
Blocks (Seattle)IL36B
SuperfamilyQ9NZH7
Human Protein AtlasENSG00000136696
Peptide AtlasQ9NZH7
HPRD05694
IPIIPI00005404   IPI00218473   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZH7
IntAct (EBI)Q9NZH7
FunCoupENSG00000136696
BioGRIDIL36B
STRING (EMBL)IL36B
ZODIACIL36B
Ontologies - Pathways
QuickGOQ9NZH7
Ontology : AmiGOcytokine activity  interleukin-1 receptor binding  extracellular region  extracellular space  inflammatory response  immune response  cytokine-mediated signaling pathway  positive regulation of interleukin-6 production  innate immune response  positive regulation of T cell differentiation  
Ontology : EGO-EBIcytokine activity  interleukin-1 receptor binding  extracellular region  extracellular space  inflammatory response  immune response  cytokine-mediated signaling pathway  positive regulation of interleukin-6 production  innate immune response  positive regulation of T cell differentiation  
NDEx NetworkIL36B
Atlas of Cancer Signalling NetworkIL36B
Wikipedia pathwaysIL36B
Orthology - Evolution
OrthoDB27177
GeneTree (enSembl)ENSG00000136696
Phylogenetic Trees/Animal Genes : TreeFamIL36B
HOVERGENQ9NZH7
HOGENOMQ9NZH7
Homologs : HomoloGeneIL36B
Homology/Alignments : Family Browser (UCSC)IL36B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL36B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL36B
dbVarIL36B
ClinVarIL36B
1000_GenomesIL36B 
Exome Variant ServerIL36B
ExAC (Exome Aggregation Consortium)IL36B (select the gene name)
Genetic variants : HAPMAP27177
Genomic Variants (DGV)IL36B [DGVbeta]
DECIPHER (Syndromes)2:113779668-113810444  ENSG00000136696
CONAN: Copy Number AnalysisIL36B 
Mutations
ICGC Data PortalIL36B 
TCGA Data PortalIL36B 
Broad Tumor PortalIL36B
OASIS PortalIL36B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL36B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL36B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL36B
DgiDB (Drug Gene Interaction Database)IL36B
DoCM (Curated mutations)IL36B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL36B (select a term)
intoGenIL36B
Cancer3DIL36B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605508   
Orphanet
MedgenIL36B
Genetic Testing Registry IL36B
NextProtQ9NZH7 [Medical]
TSGene27177
GENETestsIL36B
Huge Navigator IL36B [HugePedia]
snp3D : Map Gene to Disease27177
BioCentury BCIQIL36B
ClinGenIL36B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27177
Chemical/Pharm GKB GenePA38391
Clinical trialIL36B
Miscellaneous
canSAR (ICR)IL36B (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL36B
EVEXIL36B
GoPubMedIL36B
iHOPIL36B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:08:48 CET 2017

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