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IL36RN (interleukin 36 receptor antagonist)

Identity

Other aliasFIL1
FIL1(DELTA)
FIL1D
IL-36Ra
IL1F5
IL1HY1
IL1L1
IL1RP3
IL36RA
PSORP
PSORS14
HGNC (Hugo) IL36RN
LocusID (NCBI) 26525
Atlas_Id 56638
Location 2q14.1  [Link to chromosome band 2q14]
Location_base_pair Starts at 113059108 and ends at 113064743 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL36RN   15561
Cards
Entrez_Gene (NCBI)IL36RN  26525  interleukin 36 receptor antagonist
AliasesFIL1; FIL1(DELTA); FIL1D; IL-36Ra; 
IL1F5; IL1HY1; IL1L1; IL1RP3; IL36RA; PSORP; PSORS14
GeneCards (Weizmann)IL36RN
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:113059108-113064743 [Contig_View]  IL36RN [Vega]
TCGA cBioPortalIL36RN
AceView (NCBI)IL36RN
Genatlas (Paris)IL36RN
WikiGenes26525
SOURCE (Princeton)IL36RN
Genetics Home Reference (NIH)IL36RN
Genomic and cartography
GoldenPath hg38 (UCSC)IL36RN  -     chr2:113059108-113064743 +  2q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL36RN  -     2q14.1   [Description]    (hg19-Feb_2009)
EnsemblIL36RN - 2q14.1 [CytoView hg19]  IL36RN - 2q14.1 [CytoView hg38]
Mapping of homologs : NCBIIL36RN [Mapview hg19]  IL36RN [Mapview hg38]
OMIM605507   614204   
Gene and transcription
Genbank (Entrez)AF186094 AF201830 AF230377 AJ242737 AJ242738
RefSeq transcript (Entrez)NM_012275 NM_173170
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL36RN
Cluster EST : UnigeneHs.516301 [ NCBI ]
CGAP (NCI)Hs.516301
Gene ExpressionIL36RN [ NCBI-GEO ]   IL36RN [ EBI - ARRAY_EXPRESS ]   IL36RN [ SEEK ]   IL36RN [ MEM ]
Gene Expression Viewer (FireBrowse)IL36RN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26525
GTEX Portal (Tissue expression)IL36RN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBH0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBH0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBH0
Splice isoforms : SwissVarQ9UBH0
PhosPhoSitePlusQ9UBH0
Domaine pattern : Prosite (Expaxy)INTERLEUKIN_1 (PS00253)   
Domains : Interpro (EBI)IL-1_CS    IL-1_fam    IL-1RA/IL-36    IL-36RA    IL1/FGF   
Domain families : Pfam (Sanger)IL1 (PF00340)   
Domain families : Pfam (NCBI)pfam00340   
Conserved Domain (NCBI)IL36RN
DMDM Disease mutations26525
Blocks (Seattle)IL36RN
PDB (SRS)4P0J    4P0K    4P0L   
PDB (PDBSum)4P0J    4P0K    4P0L   
PDB (IMB)4P0J    4P0K    4P0L   
PDB (RSDB)4P0J    4P0K    4P0L   
Structural Biology KnowledgeBase4P0J    4P0K    4P0L   
SCOP (Structural Classification of Proteins)4P0J    4P0K    4P0L   
CATH (Classification of proteins structures)4P0J    4P0K    4P0L   
SuperfamilyQ9UBH0
Peptide AtlasQ9UBH0
IPIIPI00017500   IPI00917919   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBH0
IntAct (EBI)Q9UBH0
BioGRIDIL36RN
STRING (EMBL)IL36RN
ZODIACIL36RN
Ontologies - Pathways
QuickGOQ9UBH0
Ontology : AmiGOnegative regulation of cytokine-mediated signaling pathway  cytokine activity  interleukin-1 receptor binding  interleukin-1 receptor antagonist activity  protein binding  extracellular space  inflammatory response  antifungal humoral response  negative regulation of interleukin-17 production  negative regulation of interleukin-6 production  innate immune response  negative regulation of interferon-gamma secretion  
Ontology : EGO-EBInegative regulation of cytokine-mediated signaling pathway  cytokine activity  interleukin-1 receptor binding  interleukin-1 receptor antagonist activity  protein binding  extracellular space  inflammatory response  antifungal humoral response  negative regulation of interleukin-17 production  negative regulation of interleukin-6 production  innate immune response  negative regulation of interferon-gamma secretion  
NDEx NetworkIL36RN
Atlas of Cancer Signalling NetworkIL36RN
Wikipedia pathwaysIL36RN
Orthology - Evolution
OrthoDB26525
Phylogenetic Trees/Animal Genes : TreeFamIL36RN
HOVERGENQ9UBH0
HOGENOMQ9UBH0
Homologs : HomoloGeneIL36RN
Homology/Alignments : Family Browser (UCSC)IL36RN
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL36RN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL36RN
dbVarIL36RN
ClinVarIL36RN
1000_GenomesIL36RN 
Exome Variant ServerIL36RN
ExAC (Exome Aggregation Consortium)IL36RN (select the gene name)
Genetic variants : HAPMAP26525
Genomic Variants (DGV)IL36RN [DGVbeta]
DECIPHERIL36RN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL36RN 
Mutations
ICGC Data PortalIL36RN 
TCGA Data PortalIL36RN 
Broad Tumor PortalIL36RN
OASIS PortalIL36RN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL36RN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL36RN
BioMutasearch IL36RN
DgiDB (Drug Gene Interaction Database)IL36RN
DoCM (Curated mutations)IL36RN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL36RN (select a term)
intoGenIL36RN
Cancer3DIL36RN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605507    614204   
Orphanet
MedgenIL36RN
Genetic Testing Registry IL36RN
NextProtQ9UBH0 [Medical]
TSGene26525
GENETestsIL36RN
Target ValidationIL36RN
Huge Navigator IL36RN [HugePedia]
snp3D : Map Gene to Disease26525
BioCentury BCIQIL36RN
ClinGenIL36RN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26525
Chemical/Pharm GKB GenePA38388
Clinical trialIL36RN
Miscellaneous
canSAR (ICR)IL36RN (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL36RN
EVEXIL36RN
GoPubMedIL36RN
iHOPIL36RN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:38:27 CEST 2017

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