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IL37 (interleukin 37)

Identity

Alias_namesIL1F7
interleukin 1 family
Alias_symbol (synonym)FIL1
FIL1Z
FIL1(ZETA)
IL-1H4
IL-1RP1
IL-1F7
Other aliasIL-1H
IL-37
IL1H4
IL1RP1
HGNC (Hugo) IL37
LocusID (NCBI) 27178
Atlas_Id 52265
Location 2q14.1  [Link to chromosome band 2q14]
Location_base_pair Starts at 112912971 and ends at 112918881 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL37   15563
Cards
Entrez_Gene (NCBI)IL37  27178  interleukin 37
AliasesFIL1; FIL1(ZETA); FIL1Z; IL-1F7; 
IL-1H; IL-1H4; IL-1RP1; IL-37; IL1F7; IL1H4; IL1RP1
GeneCards (Weizmann)IL37
Ensembl hg19 (Hinxton)ENSG00000125571 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125571 [Gene_View]  chr2:112912971-112918881 [Contig_View]  IL37 [Vega]
ICGC DataPortalENSG00000125571
TCGA cBioPortalIL37
AceView (NCBI)IL37
Genatlas (Paris)IL37
WikiGenes27178
SOURCE (Princeton)IL37
Genetics Home Reference (NIH)IL37
Genomic and cartography
GoldenPath hg38 (UCSC)IL37  -     chr2:112912971-112918881 +  2q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL37  -     2q14.1   [Description]    (hg19-Feb_2009)
EnsemblIL37 - 2q14.1 [CytoView hg19]  IL37 - 2q14.1 [CytoView hg38]
Mapping of homologs : NCBIIL37 [Mapview hg19]  IL37 [Mapview hg38]
OMIM605510   
Gene and transcription
Genbank (Entrez)AB451333 AB451478 AF167368 AF200496 AF201832
RefSeq transcript (Entrez)NM_014439 NM_173202 NM_173203 NM_173204 NM_173205
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IL37
Cluster EST : UnigeneHs.166371 [ NCBI ]
CGAP (NCI)Hs.166371
Alternative Splicing GalleryENSG00000125571
Gene ExpressionIL37 [ NCBI-GEO ]   IL37 [ EBI - ARRAY_EXPRESS ]   IL37 [ SEEK ]   IL37 [ MEM ]
Gene Expression Viewer (FireBrowse)IL37 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27178
GTEX Portal (Tissue expression)IL37
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZH6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZH6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZH6
Splice isoforms : SwissVarQ9NZH6
PhosPhoSitePlusQ9NZH6
Domains : Interpro (EBI)IL-1_fam    IL-1RA/IL-36    IL-37    IL1/FGF   
Domain families : Pfam (Sanger)IL1 (PF00340)   
Domain families : Pfam (NCBI)pfam00340   
Conserved Domain (NCBI)IL37
DMDM Disease mutations27178
Blocks (Seattle)IL37
SuperfamilyQ9NZH6
Human Protein AtlasENSG00000125571
Peptide AtlasQ9NZH6
HPRD05695
IPIIPI00218391   IPI00218392   IPI00218393   IPI00218394   IPI00016741   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZH6
IntAct (EBI)Q9NZH6
FunCoupENSG00000125571
BioGRIDIL37
STRING (EMBL)IL37
ZODIACIL37
Ontologies - Pathways
QuickGOQ9NZH6
Ontology : AmiGOcytokine activity  interleukin-1 receptor binding  interleukin-1 receptor binding  extracellular region  extracellular region  extracellular space  nucleoplasm  cytosol  inflammatory response  immune response  cytokine-mediated signaling pathway  intracellular membrane-bounded organelle  
Ontology : EGO-EBIcytokine activity  interleukin-1 receptor binding  interleukin-1 receptor binding  extracellular region  extracellular region  extracellular space  nucleoplasm  cytosol  inflammatory response  immune response  cytokine-mediated signaling pathway  intracellular membrane-bounded organelle  
NDEx NetworkIL37
Atlas of Cancer Signalling NetworkIL37
Wikipedia pathwaysIL37
Orthology - Evolution
OrthoDB27178
GeneTree (enSembl)ENSG00000125571
Phylogenetic Trees/Animal Genes : TreeFamIL37
HOVERGENQ9NZH6
HOGENOMQ9NZH6
Homologs : HomoloGeneIL37
Homology/Alignments : Family Browser (UCSC)IL37
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL37 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL37
dbVarIL37
ClinVarIL37
1000_GenomesIL37 
Exome Variant ServerIL37
ExAC (Exome Aggregation Consortium)IL37 (select the gene name)
Genetic variants : HAPMAP27178
Genomic Variants (DGV)IL37 [DGVbeta]
DECIPHERIL37 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL37 
Mutations
ICGC Data PortalIL37 
TCGA Data PortalIL37 
Broad Tumor PortalIL37
OASIS PortalIL37 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL37  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL37
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IL37
DgiDB (Drug Gene Interaction Database)IL37
DoCM (Curated mutations)IL37 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL37 (select a term)
intoGenIL37
Cancer3DIL37(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605510   
Orphanet
MedgenIL37
Genetic Testing Registry IL37
NextProtQ9NZH6 [Medical]
TSGene27178
GENETestsIL37
Huge Navigator IL37 [HugePedia]
snp3D : Map Gene to Disease27178
BioCentury BCIQIL37
ClinGenIL37
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27178
Chemical/Pharm GKB GenePA38390
Clinical trialIL37
Miscellaneous
canSAR (ICR)IL37 (select the gene name)
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL37
EVEXIL37
GoPubMedIL37
iHOPIL37
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:20:25 CEST 2017

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