Atlas of Genetics and Cytogenetics in Oncology and Haematology


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IL4I1 (interleukin 4 induced 1)

Identity

Alias_symbol (synonym)FIG1
Other aliasLAAO
LAO
HGNC (Hugo) IL4I1
LocusID (NCBI) 259307
Atlas_Id 43872
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 50392913 and ends at 50432796 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
IL4I1 (19q13.33) / CSTB (21q22.3)IL4I1 (19q13.33) / IL4I1 (19q13.33)IL4I1 (19q13.33) / KCNQ2 (20q13.33)
IL4I1 (19q13.33) / KCTD2 (17q25.1)IL4I1 (19q13.33) / TUBB6 (18p11.21)LOC100507412 (-) / IL4I1 (19q13.33)
TOR1AIP2 (1q25.2) / IL4I1 (19q13.33)IL4I1 19q13.33 / KCNQ2 20q13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IL4I1   19094
Cards
Entrez_Gene (NCBI)IL4I1  259307  interleukin 4 induced 1
AliasesFIG1; LAAO; LAO
GeneCards (Weizmann)IL4I1
Ensembl hg19 (Hinxton)ENSG00000104951 [Gene_View]  chr19:50392913-50432796 [Contig_View]  IL4I1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104951 [Gene_View]  chr19:50392913-50432796 [Contig_View]  IL4I1 [Vega]
ICGC DataPortalENSG00000104951
TCGA cBioPortalIL4I1
AceView (NCBI)IL4I1
Genatlas (Paris)IL4I1
WikiGenes259307
SOURCE (Princeton)IL4I1
Genetics Home Reference (NIH)IL4I1
Genomic and cartography
GoldenPath hg19 (UCSC)IL4I1  -     chr19:50392913-50432796 -  19q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)IL4I1  -     19q13.33   [Description]    (hg38-Dec_2013)
EnsemblIL4I1 - 19q13.33 [CytoView hg19]  IL4I1 - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBIIL4I1 [Mapview hg19]  IL4I1 [Mapview hg38]
OMIM609742   
Gene and transcription
Genbank (Entrez)AF293462 AJ880386 AJ880387 AJ880388 AJ880389
RefSeq transcript (Entrez)NM_001258017 NM_001258018 NM_152899 NM_172374
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_021170 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)IL4I1
Cluster EST : UnigeneHs.741750 [ NCBI ]
CGAP (NCI)Hs.741750
Alternative Splicing GalleryENSG00000104951
Gene ExpressionIL4I1 [ NCBI-GEO ]   IL4I1 [ EBI - ARRAY_EXPRESS ]   IL4I1 [ SEEK ]   IL4I1 [ MEM ]
Gene Expression Viewer (FireBrowse)IL4I1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)259307
GTEX Portal (Tissue expression)IL4I1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96RQ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96RQ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96RQ9
Splice isoforms : SwissVarQ96RQ9
Catalytic activity : Enzyme1.4.3.2 [ Enzyme-Expasy ]   1.4.3.21.4.3.2 [ IntEnz-EBI ]   1.4.3.2 [ BRENDA ]   1.4.3.2 [ KEGG ]   
PhosPhoSitePlusQ96RQ9
Domains : Interpro (EBI)Amino_oxidase    FAD/NAD-binding_dom    Flavin_amine_oxidase   
Domain families : Pfam (Sanger)Amino_oxidase (PF01593)   
Domain families : Pfam (NCBI)pfam01593   
Conserved Domain (NCBI)IL4I1
DMDM Disease mutations259307
Blocks (Seattle)IL4I1
PDB (SRS)2I8H   
PDB (PDBSum)2I8H   
PDB (IMB)2I8H   
PDB (RSDB)2I8H   
Structural Biology KnowledgeBase2I8H   
SCOP (Structural Classification of Proteins)2I8H   
CATH (Classification of proteins structures)2I8H   
SuperfamilyQ96RQ9
Human Protein AtlasENSG00000104951
Peptide AtlasQ96RQ9
HPRD17146
IPIIPI00045464   IPI00414928   
Protein Interaction databases
DIP (DOE-UCLA)Q96RQ9
IntAct (EBI)Q96RQ9
FunCoupENSG00000104951
BioGRIDIL4I1
STRING (EMBL)IL4I1
ZODIACIL4I1
Ontologies - Pathways
QuickGOQ96RQ9
Ontology : AmiGOL-amino-acid oxidase activity  extracellular region  lysosome  L-phenylalanine catabolic process  oxidation-reduction process  
Ontology : EGO-EBIL-amino-acid oxidase activity  extracellular region  lysosome  L-phenylalanine catabolic process  oxidation-reduction process  
Pathways : KEGGAlanine, aspartate and glutamate metabolism    Cysteine and methionine metabolism    Valine, leucine and isoleucine degradation    Tyrosine metabolism    Phenylalanine metabolism    Tryptophan metabolism    Phenylalanine, tyrosine and tryptophan biosynthesis   
NDEx NetworkIL4I1
Atlas of Cancer Signalling NetworkIL4I1
Wikipedia pathwaysIL4I1
Orthology - Evolution
OrthoDB259307
GeneTree (enSembl)ENSG00000104951
Phylogenetic Trees/Animal Genes : TreeFamIL4I1
HOVERGENQ96RQ9
HOGENOMQ96RQ9
Homologs : HomoloGeneIL4I1
Homology/Alignments : Family Browser (UCSC)IL4I1
Gene fusions - Rearrangements
Fusion : MitelmanIL4I1/KCNQ2 [19q13.33/20q13.33]  
Fusion: TCGAIL4I1 19q13.33 KCNQ2 20q13.33 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL4I1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL4I1
dbVarIL4I1
ClinVarIL4I1
1000_GenomesIL4I1 
Exome Variant ServerIL4I1
ExAC (Exome Aggregation Consortium)IL4I1 (select the gene name)
Genetic variants : HAPMAP259307
Genomic Variants (DGV)IL4I1 [DGVbeta]
DECIPHER (Syndromes)19:50392913-50432796  ENSG00000104951
CONAN: Copy Number AnalysisIL4I1 
Mutations
ICGC Data PortalIL4I1 
TCGA Data PortalIL4I1 
Broad Tumor PortalIL4I1
OASIS PortalIL4I1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL4I1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIL4I1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch IL4I1
DgiDB (Drug Gene Interaction Database)IL4I1
DoCM (Curated mutations)IL4I1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IL4I1 (select a term)
intoGenIL4I1
Cancer3DIL4I1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609742   
Orphanet
MedgenIL4I1
Genetic Testing Registry IL4I1
NextProtQ96RQ9 [Medical]
TSGene259307
GENETestsIL4I1
Huge Navigator IL4I1 [HugePedia]
snp3D : Map Gene to Disease259307
BioCentury BCIQIL4I1
ClinGenIL4I1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD259307
Chemical/Pharm GKB GenePA38795
Clinical trialIL4I1
Miscellaneous
canSAR (ICR)IL4I1 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIL4I1
EVEXIL4I1
GoPubMedIL4I1
iHOPIL4I1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:10:45 CET 2017

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