Atlas of Genetics and Cytogenetics in Oncology and Haematology


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IL4I1 (interleukin 4 induced 1)

Identity

Alias (NCBI)FIG1
LAAO
LAO
hIL4I1
HGNC (Hugo) IL4I1
HGNC Alias symbFIG1
LocusID (NCBI) 259307
Atlas_Id 43872
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 49889656 and ends at 49929504 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IL4I1 (19q13.33) / CSTB (21q22.3)IL4I1 (19q13.33) / IL4I1 (19q13.33)IL4I1 (19q13.33) / KCNQ2 (20q13.33)
IL4I1 (19q13.33) / KCTD2 (17q25.1)IL4I1 (19q13.33) / TUBB6 (18p11.21)LOC100507412 (-) / IL4I1 (19q13.33)
TOR1AIP2 (1q25.2) / IL4I1 (19q13.33)IL4I1 19q13.33 / KCNQ2 20q13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)IL4I1   19094
Cards
Entrez_Gene (NCBI)IL4I1    interleukin 4 induced 1
AliasesFIG1; LAAO; LAO; hIL4I1
GeneCards (Weizmann)IL4I1
Ensembl hg19 (Hinxton)ENSG00000104951 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104951 [Gene_View]  ENSG00000104951 [Sequence]  chr19:49889656-49929504 [Contig_View]  IL4I1 [Vega]
ICGC DataPortalENSG00000104951
TCGA cBioPortalIL4I1
AceView (NCBI)IL4I1
Genatlas (Paris)IL4I1
SOURCE (Princeton)IL4I1
Genetics Home Reference (NIH)IL4I1
Genomic and cartography
GoldenPath hg38 (UCSC)IL4I1  -     chr19:49889656-49929504 -  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL4I1  -     19q13.33   [Description]    (hg19-Feb_2009)
GoldenPathIL4I1 - 19q13.33 [CytoView hg19]  IL4I1 - 19q13.33 [CytoView hg38]
ImmunoBaseENSG00000104951
Genome Data Viewer NCBIIL4I1 [Mapview hg19]  
OMIM609742   
Gene and transcription
Genbank (Entrez)AF293462 AJ880386 AJ880387 AJ880388 AJ880389
RefSeq transcript (Entrez)NM_001258017 NM_001258018 NM_001385639 NM_152899 NM_172374
Consensus coding sequences : CCDS (NCBI)IL4I1
Gene ExpressionIL4I1 [ NCBI-GEO ]   IL4I1 [ EBI - ARRAY_EXPRESS ]   IL4I1 [ SEEK ]   IL4I1 [ MEM ]
Gene Expression Viewer (FireBrowse)IL4I1 [ Firebrowse - Broad ]
GenevisibleExpression of IL4I1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)259307
GTEX Portal (Tissue expression)IL4I1
Human Protein AtlasENSG00000104951-IL4I1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96RQ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96RQ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96RQ9
PhosPhoSitePlusQ96RQ9
Domains : Interpro (EBI)Amino_oxidase    FAD/NAD-bd_sf    Flavin_amine_oxidase   
Domain families : Pfam (Sanger)Amino_oxidase (PF01593)   
Domain families : Pfam (NCBI)pfam01593   
Conserved Domain (NCBI)IL4I1
PDB (RSDB)2I8H   
PDB Europe2I8H   
PDB (PDBSum)2I8H   
PDB (IMB)2I8H   
Structural Biology KnowledgeBase2I8H   
SCOP (Structural Classification of Proteins)2I8H   
CATH (Classification of proteins structures)2I8H   
SuperfamilyQ96RQ9
AlphaFold pdb e-kbQ96RQ9   
Human Protein Atlas [tissue]ENSG00000104951-IL4I1 [tissue]
HPRD17146
Protein Interaction databases
DIP (DOE-UCLA)Q96RQ9
IntAct (EBI)Q96RQ9
BioGRIDIL4I1
STRING (EMBL)IL4I1
ZODIACIL4I1
Ontologies - Pathways
QuickGOQ96RQ9
Ontology : AmiGOacrosomal vesicle  L-amino-acid oxidase activity  L-amino-acid oxidase activity  immunological synapse  adaptive immune response  regulation of adaptive immune response  negative regulation of T cell mediated immune response to tumor cell  protein binding  extracellular region  extracellular region  lysosome  L-phenylalanine metabolic process  L-phenylalanine catabolic process  tryptophan catabolic process  tyrosine catabolic process  cellular amino acid catabolic process  oxidoreductase activity  tryptophan catabolic process to indole-3-acetate  negative regulation of T cell proliferation  regulation of B cell differentiation  positive regulation of regulatory T cell differentiation  positive regulation of transcription by RNA polymerase II  polyamine oxidase activity  negative regulation of T cell activation  sperm midpiece  L-phenylalaine oxidase activity  
Ontology : EGO-EBIacrosomal vesicle  L-amino-acid oxidase activity  L-amino-acid oxidase activity  immunological synapse  adaptive immune response  regulation of adaptive immune response  negative regulation of T cell mediated immune response to tumor cell  protein binding  extracellular region  extracellular region  lysosome  L-phenylalanine metabolic process  L-phenylalanine catabolic process  tryptophan catabolic process  tyrosine catabolic process  cellular amino acid catabolic process  oxidoreductase activity  tryptophan catabolic process to indole-3-acetate  negative regulation of T cell proliferation  regulation of B cell differentiation  positive regulation of regulatory T cell differentiation  positive regulation of transcription by RNA polymerase II  polyamine oxidase activity  negative regulation of T cell activation  sperm midpiece  L-phenylalaine oxidase activity  
Pathways : KEGGAlanine, aspartate and glutamate metabolism    Cysteine and methionine metabolism    Valine, leucine and isoleucine degradation    Tyrosine metabolism    Phenylalanine metabolism    Tryptophan metabolism    Phenylalanine, tyrosine and tryptophan biosynthesis   
NDEx NetworkIL4I1
Atlas of Cancer Signalling NetworkIL4I1
Wikipedia pathwaysIL4I1
Orthology - Evolution
OrthoDB259307
GeneTree (enSembl)ENSG00000104951
Phylogenetic Trees/Animal Genes : TreeFamIL4I1
Homologs : HomoloGeneIL4I1
Homology/Alignments : Family Browser (UCSC)IL4I1
Gene fusions - Rearrangements
Fusion : MitelmanIL4I1/KCNQ2 [19q13.33/20q13.33]  
Fusion : QuiverIL4I1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL4I1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL4I1
dbVarIL4I1
ClinVarIL4I1
MonarchIL4I1
1000_GenomesIL4I1 
Exome Variant ServerIL4I1
GNOMAD BrowserENSG00000104951
Varsome BrowserIL4I1
ACMGIL4I1 variants
VarityQ96RQ9
Genomic Variants (DGV)IL4I1 [DGVbeta]
DECIPHERIL4I1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL4I1 
Mutations
ICGC Data PortalIL4I1 
TCGA Data PortalIL4I1 
Broad Tumor PortalIL4I1
OASIS PortalIL4I1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL4I1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIL4I1
Mutations and Diseases : HGMDIL4I1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaIL4I1
DgiDB (Drug Gene Interaction Database)IL4I1
DoCM (Curated mutations)IL4I1
CIViC (Clinical Interpretations of Variants in Cancer)IL4I1
Cancer3DIL4I1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609742   
Orphanet
DisGeNETIL4I1
MedgenIL4I1
Genetic Testing Registry IL4I1
NextProtQ96RQ9 [Medical]
GENETestsIL4I1
Target ValidationIL4I1
Huge Navigator IL4I1 [HugePedia]
ClinGenIL4I1
Clinical trials, drugs, therapy
MyCancerGenomeIL4I1
Protein Interactions : CTDIL4I1
Pharm GKB GenePA38795
PharosQ96RQ9
Clinical trialIL4I1
Miscellaneous
canSAR (ICR)IL4I1
HarmonizomeIL4I1
DataMed IndexIL4I1
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIL4I1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:13:52 CEST 2021

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