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IL9 (interleukin 9)

Identity

Alias (NCBI)HP40
IL-9
P40
HGNC (Hugo) IL9
HGNC Alias symbIL-9
HP40
P40
HGNC Alias namep40 T-cell and mast cell growth factor
 T-cell growth factor p40
 p40 cytokine
 homolog of mouse T cell and mast cell growth factor 40
LocusID (NCBI) 3578
Atlas_Id 40968
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 135892246 and ends at 135895841 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HBS1L (6q23.3)::IL9 (5q31.1)HBS1L 6q23.3::IL9 5q31.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)IL9   6029
Cards
Entrez_Gene (NCBI)IL9    interleukin 9
AliasesHP40; IL-9; P40
GeneCards (Weizmann)IL9
Ensembl hg19 (Hinxton)ENSG00000145839 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145839 [Gene_View]  ENSG00000145839 [Sequence]  chr5:135892246-135895841 [Contig_View]  IL9 [Vega]
ICGC DataPortalENSG00000145839
TCGA cBioPortalIL9
AceView (NCBI)IL9
Genatlas (Paris)IL9
SOURCE (Princeton)IL9
Genetics Home Reference (NIH)IL9
Genomic and cartography
GoldenPath hg38 (UCSC)IL9  -     chr5:135892246-135895841 -  5q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IL9  -     5q31.1   [Description]    (hg19-Feb_2009)
GoldenPathIL9 - 5q31.1 [CytoView hg19]  IL9 - 5q31.1 [CytoView hg38]
ImmunoBaseENSG00000145839
Genome Data Viewer NCBIIL9 [Mapview hg19]  
OMIM146931   
Gene and transcription
Genbank (Entrez)BC066283 BC066284 BC066285 BC066286 BC066287
RefSeq transcript (Entrez)NM_000590
Consensus coding sequences : CCDS (NCBI)IL9
Gene ExpressionIL9 [ NCBI-GEO ]   IL9 [ EBI - ARRAY_EXPRESS ]   IL9 [ SEEK ]   IL9 [ MEM ]
Gene Expression Viewer (FireBrowse)IL9 [ Firebrowse - Broad ]
GenevisibleExpression of IL9 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3578
GTEX Portal (Tissue expression)IL9
Human Protein AtlasENSG00000145839-IL9 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15248   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15248  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15248
PhosPhoSitePlusP15248
Domaine pattern : Prosite (Expaxy)INTERLEUKIN_7_9 (PS00255)   
Domains : Interpro (EBI)IL-7/IL-9_CS    IL-9   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)IL9
SuperfamilyP15248
AlphaFold pdb e-kbP15248   
Human Protein Atlas [tissue]ENSG00000145839-IL9 [tissue]
HPRD00910
Protein Interaction databases
DIP (DOE-UCLA)P15248
IntAct (EBI)P15248
BioGRIDIL9
STRING (EMBL)IL9
ZODIACIL9
Ontologies - Pathways
QuickGOP15248
Ontology : AmiGOcytokine activity  interleukin-9 receptor binding  extracellular region  extracellular space  inflammatory response  signal transduction  growth factor activity  positive regulation of cell population proliferation  immunoglobulin mediated immune response  B cell differentiation  positive regulation of cell growth  positive regulation of interleukin-5 production  B cell proliferation  regulation of receptor signaling pathway via JAK-STAT  regulation of peptidyl-tyrosine phosphorylation  negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway  
Ontology : EGO-EBIcytokine activity  interleukin-9 receptor binding  extracellular region  extracellular space  inflammatory response  signal transduction  growth factor activity  positive regulation of cell population proliferation  immunoglobulin mediated immune response  B cell differentiation  positive regulation of cell growth  positive regulation of interleukin-5 production  B cell proliferation  regulation of receptor signaling pathway via JAK-STAT  regulation of peptidyl-tyrosine phosphorylation  negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway  
Pathways : BIOCARTABIOCARTA_CYTOKINEPATHWAY    BIOCARTA_ERYTHPATHWAY    BIOCARTA_STEMPATHWAY   
Pathways : KEGGKEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION    KEGG_JAK_STAT_SIGNALING    KEGG_ASTHMA   
NDEx NetworkIL9
Atlas of Cancer Signalling NetworkIL9
Wikipedia pathwaysIL9
Orthology - Evolution
OrthoDB3578
GeneTree (enSembl)ENSG00000145839
Phylogenetic Trees/Animal Genes : TreeFamIL9
Homologs : HomoloGeneIL9
Homology/Alignments : Family Browser (UCSC)IL9
Gene fusions - Rearrangements
Fusion : MitelmanHBS1L::IL9 [6q23.3/5q31.1]  
Fusion : QuiverIL9
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIL9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IL9
dbVarIL9
ClinVarIL9
MonarchIL9
1000_GenomesIL9 
Exome Variant ServerIL9
GNOMAD BrowserENSG00000145839
Varsome BrowserIL9
ACMGIL9 variants
VarityP15248
Genomic Variants (DGV)IL9 [DGVbeta]
DECIPHERIL9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIL9 
Mutations
ICGC Data PortalIL9 
TCGA Data PortalIL9 
Broad Tumor PortalIL9
OASIS PortalIL9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIL9  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIL9
Mutations and Diseases : HGMDIL9
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaIL9
DgiDB (Drug Gene Interaction Database)IL9
DoCM (Curated mutations)IL9
CIViC (Clinical Interpretations of Variants in Cancer)IL9
Cancer3DIL9
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM146931   
Orphanet
DisGeNETIL9
MedgenIL9
Genetic Testing Registry IL9
NextProtP15248 [Medical]
GENETestsIL9
Target ValidationIL9
Huge Navigator IL9 [HugePedia]
ClinGenIL9
Clinical trials, drugs, therapy
MyCancerGenomeIL9
Protein Interactions : CTDIL9
Pharm GKB GenePA29845
PharosP15248
Clinical trialIL9
Miscellaneous
canSAR (ICR)IL9
HarmonizomeIL9
ARCHS4IL9
DataMed IndexIL9
Probes
Litterature
PubMed179 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIL9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:38:35 CET 2022

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