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ILF3 (interleukin enhancer binding factor 3)

Identity

Alias_namesinterleukin enhancer binding factor 3, 90kD
interleukin enhancer binding factor 3, 90kDa
Alias_symbol (synonym)NF90
MPHOSPH4
MPP4
DRBP76
NFAR-1
Other aliasCBTF
DRBF
MMP4
NF-AT-90
NF110
NF110b
NF90a
NF90b
NFAR
NFAR2
TCP110
TCP80
HGNC (Hugo) ILF3
LocusID (NCBI) 3609
Atlas_Id 52550
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 10764937 and ends at 10796443 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
C17orf80 (17q25.1) / ILF3 (19p13.2)DNM2 (19p13.2) / ILF3 (19p13.2)ILF3 (19p13.2) / C17orf80 (17q25.1)
ILF3 (19p13.2) / C3 (19p13.3)ILF3 (19p13.2) / ILF3 (19p13.2)ILF3 (19p13.2) / TOP2A (17q21.2)
LIMCH1 (4p13) / ILF3 (19p13.2)SENP1 (12q13.11) / ILF3 (19p13.2)SERPING1 (11q12.1) / ILF3 (19p13.2)
TPI1 (12p13.31) / ILF3 (19p13.2)ZNF708 (19p12) / ILF3 (19p13.2)DNM2 19p13.2 / ILF3 19p13.2
ILF3 19p13.2 / C3 19p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ILF3   6038
Cards
Entrez_Gene (NCBI)ILF3  3609  interleukin enhancer binding factor 3
AliasesCBTF; DRBF; DRBP76; MMP4; 
MPHOSPH4; MPP4; NF-AT-90; NF110; NF110b; NF90; NF90a; NF90b; NFAR; NFAR-1; NFAR2; TCP110; TCP80
GeneCards (Weizmann)ILF3
Ensembl hg19 (Hinxton)ENSG00000129351 [Gene_View]  chr19:10764937-10796443 [Contig_View]  ILF3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000129351 [Gene_View]  chr19:10764937-10796443 [Contig_View]  ILF3 [Vega]
ICGC DataPortalENSG00000129351
TCGA cBioPortalILF3
AceView (NCBI)ILF3
Genatlas (Paris)ILF3
WikiGenes3609
SOURCE (Princeton)ILF3
Genetics Home Reference (NIH)ILF3
Genomic and cartography
GoldenPath hg19 (UCSC)ILF3  -     chr19:10764937-10796443 +  19p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ILF3  -     19p13.2   [Description]    (hg38-Dec_2013)
EnsemblILF3 - 19p13.2 [CytoView hg19]  ILF3 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIILF3 [Mapview hg19]  ILF3 [Mapview hg38]
OMIM603182   
Gene and transcription
Genbank (Entrez)AB209062 AF007140 AF141870 AF147209 AF167569
RefSeq transcript (Entrez)NM_001137673 NM_004516 NM_012218 NM_017620 NM_153464
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_029220 NT_011295 NW_004929414
Consensus coding sequences : CCDS (NCBI)ILF3
Cluster EST : UnigeneHs.465885 [ NCBI ]
CGAP (NCI)Hs.465885
Alternative Splicing GalleryENSG00000129351
Gene ExpressionILF3 [ NCBI-GEO ]   ILF3 [ EBI - ARRAY_EXPRESS ]   ILF3 [ SEEK ]   ILF3 [ MEM ]
Gene Expression Viewer (FireBrowse)ILF3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3609
GTEX Portal (Tissue expression)ILF3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12906   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12906  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12906
Splice isoforms : SwissVarQ12906
PhosPhoSitePlusQ12906
Domaine pattern : Prosite (Expaxy)DS_RBD (PS50137)    DZF (PS51703)   
Domains : Interpro (EBI)dsRBD_dom    DZF_dom   
Domain families : Pfam (Sanger)dsrm (PF00035)    DZF (PF07528)   
Domain families : Pfam (NCBI)pfam00035    pfam07528   
Domain families : Smart (EMBL)DSRM (SM00358)  DZF (SM00572)  
Conserved Domain (NCBI)ILF3
DMDM Disease mutations3609
Blocks (Seattle)ILF3
PDB (SRS)2L33    3P1X   
PDB (PDBSum)2L33    3P1X   
PDB (IMB)2L33    3P1X   
PDB (RSDB)2L33    3P1X   
Structural Biology KnowledgeBase2L33    3P1X   
SCOP (Structural Classification of Proteins)2L33    3P1X   
CATH (Classification of proteins structures)2L33    3P1X   
SuperfamilyQ12906
Human Protein AtlasENSG00000129351
Peptide AtlasQ12906
HPRD04420
IPIIPI00298788   IPI00298789   IPI00414335   IPI01018179   IPI00219330   IPI00556173   IPI00556364   IPI00386121   IPI00418313   
Protein Interaction databases
DIP (DOE-UCLA)Q12906
IntAct (EBI)Q12906
FunCoupENSG00000129351
BioGRIDILF3
STRING (EMBL)ILF3
ZODIACILF3
Ontologies - Pathways
QuickGOQ12906
Ontology : AmiGODNA binding  RNA binding  double-stranded RNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleolus  cytoplasm  mitochondrion  transcription, DNA-templated  protein phosphorylation  membrane  negative regulation of translation  intracellular ribonucleoprotein complex  poly(A) RNA binding  negative regulation of viral genome replication  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  defense response to virus  
Ontology : EGO-EBIDNA binding  RNA binding  double-stranded RNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleolus  cytoplasm  mitochondrion  transcription, DNA-templated  protein phosphorylation  membrane  negative regulation of translation  intracellular ribonucleoprotein complex  poly(A) RNA binding  negative regulation of viral genome replication  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  defense response to virus  
NDEx NetworkILF3
Atlas of Cancer Signalling NetworkILF3
Wikipedia pathwaysILF3
Orthology - Evolution
OrthoDB3609
GeneTree (enSembl)ENSG00000129351
Phylogenetic Trees/Animal Genes : TreeFamILF3
HOVERGENQ12906
HOGENOMQ12906
Homologs : HomoloGeneILF3
Homology/Alignments : Family Browser (UCSC)ILF3
Gene fusions - Rearrangements
Fusion : MitelmanDNM2/ILF3 [19p13.2/19p13.2]  [t(19;19)(p13;p13)]  
Fusion : MitelmanILF3/C3 [19p13.2/19p13.3]  [t(19;19)(p13;p13)]  
Fusion: TCGADNM2 19p13.2 ILF3 19p13.2 BRCA
Fusion: TCGAILF3 19p13.2 C3 19p13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerILF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ILF3
dbVarILF3
ClinVarILF3
1000_GenomesILF3 
Exome Variant ServerILF3
ExAC (Exome Aggregation Consortium)ILF3 (select the gene name)
Genetic variants : HAPMAP3609
Genomic Variants (DGV)ILF3 [DGVbeta]
DECIPHER (Syndromes)19:10764937-10796443  ENSG00000129351
CONAN: Copy Number AnalysisILF3 
Mutations
ICGC Data PortalILF3 
TCGA Data PortalILF3 
Broad Tumor PortalILF3
OASIS PortalILF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICILF3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDILF3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ILF3
DgiDB (Drug Gene Interaction Database)ILF3
DoCM (Curated mutations)ILF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ILF3 (select a term)
intoGenILF3
Cancer3DILF3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603182   
Orphanet
MedgenILF3
Genetic Testing Registry ILF3
NextProtQ12906 [Medical]
TSGene3609
GENETestsILF3
Huge Navigator ILF3 [HugePedia]
snp3D : Map Gene to Disease3609
BioCentury BCIQILF3
ClinGenILF3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3609
Chemical/Pharm GKB GenePA29853
Clinical trialILF3
Miscellaneous
canSAR (ICR)ILF3 (select the gene name)
Probes
Litterature
PubMed154 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineILF3
EVEXILF3
GoPubMedILF3
iHOPILF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:10:47 CET 2017

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