Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IMPA1 (inositol monophosphatase 1)

Identity

Alias_namesIMPA
inositol(myo)-1(or 4)-monophosphatase 1
Other aliasIMP
MRT59
HGNC (Hugo) IMPA1
LocusID (NCBI) 3612
Atlas_Id 40971
Location 8q21.13  [Link to chromosome band 8q21]
Location_base_pair Starts at 81656916 and ends at 81686354 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ZNF704 (8q21.13) / IMPA1 (8q21.13)ZNF704 8q21.13 / IMPA1 8q21.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IMPA1   6050
Cards
Entrez_Gene (NCBI)IMPA1  3612  inositol monophosphatase 1
AliasesIMP; IMPA; MRT59
GeneCards (Weizmann)IMPA1
Ensembl hg19 (Hinxton)ENSG00000133731 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133731 [Gene_View]  chr8:81656916-81686354 [Contig_View]  IMPA1 [Vega]
ICGC DataPortalENSG00000133731
TCGA cBioPortalIMPA1
AceView (NCBI)IMPA1
Genatlas (Paris)IMPA1
WikiGenes3612
SOURCE (Princeton)IMPA1
Genetics Home Reference (NIH)IMPA1
Genomic and cartography
GoldenPath hg38 (UCSC)IMPA1  -     chr8:81656916-81686354 -  8q21.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IMPA1  -     8q21.13   [Description]    (hg19-Feb_2009)
EnsemblIMPA1 - 8q21.13 [CytoView hg19]  IMPA1 - 8q21.13 [CytoView hg38]
Mapping of homologs : NCBIIMPA1 [Mapview hg19]  IMPA1 [Mapview hg38]
OMIM602064   617323   
Gene and transcription
Genbank (Entrez)AF042729 AI921211 AK297078 AK300750 AK312823
RefSeq transcript (Entrez)NM_001144878 NM_001144879 NM_005536
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IMPA1
Cluster EST : UnigeneHs.656694 [ NCBI ]
CGAP (NCI)Hs.656694
Alternative Splicing GalleryENSG00000133731
Gene ExpressionIMPA1 [ NCBI-GEO ]   IMPA1 [ EBI - ARRAY_EXPRESS ]   IMPA1 [ SEEK ]   IMPA1 [ MEM ]
Gene Expression Viewer (FireBrowse)IMPA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3612
GTEX Portal (Tissue expression)IMPA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP29218   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP29218  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP29218
Splice isoforms : SwissVarP29218
PhosPhoSitePlusP29218
Domaine pattern : Prosite (Expaxy)IMP_1 (PS00629)    IMP_2 (PS00630)   
Domains : Interpro (EBI)IMPase    Inositol_monoP_metal-BS    Inositol_monoPase_Li-sen    Inositol_monophosphatase-like    Inositol_monophosphatase_CS   
Domain families : Pfam (Sanger)Inositol_P (PF00459)   
Domain families : Pfam (NCBI)pfam00459   
Conserved Domain (NCBI)IMPA1
DMDM Disease mutations3612
Blocks (Seattle)IMPA1
PDB (SRS)1AWB    1IMA    1IMB    1IMC    1IMD    1IME    1IMF    2HHM    4AS4   
PDB (PDBSum)1AWB    1IMA    1IMB    1IMC    1IMD    1IME    1IMF    2HHM    4AS4   
PDB (IMB)1AWB    1IMA    1IMB    1IMC    1IMD    1IME    1IMF    2HHM    4AS4   
PDB (RSDB)1AWB    1IMA    1IMB    1IMC    1IMD    1IME    1IMF    2HHM    4AS4   
Structural Biology KnowledgeBase1AWB    1IMA    1IMB    1IMC    1IMD    1IME    1IMF    2HHM    4AS4   
SCOP (Structural Classification of Proteins)1AWB    1IMA    1IMB    1IMC    1IMD    1IME    1IMF    2HHM    4AS4   
CATH (Classification of proteins structures)1AWB    1IMA    1IMB    1IMC    1IMD    1IME    1IMF    2HHM    4AS4   
SuperfamilyP29218
Human Protein AtlasENSG00000133731
Peptide AtlasP29218
HPRD03641
IPIIPI00020906   IPI00791997   IPI00921428   IPI00974217   IPI00974011   IPI00790217   IPI00976418   IPI00974167   IPI00978875   IPI00974104   IPI01013995   
Protein Interaction databases
DIP (DOE-UCLA)P29218
IntAct (EBI)P29218
FunCoupENSG00000133731
BioGRIDIMPA1
STRING (EMBL)IMPA1
ZODIACIMPA1
Ontologies - Pathways
QuickGOP29218
Ontology : AmiGOmagnesium ion binding  protein binding  cytoplasm  cytosol  inositol metabolic process  inositol biosynthetic process  phosphatidylinositol biosynthetic process  phosphate-containing compound metabolic process  signal transduction  inositol monophosphate 1-phosphatase activity  inositol monophosphate 1-phosphatase activity  inositol monophosphate 1-phosphatase activity  manganese ion binding  lithium ion binding  identical protein binding  protein homodimerization activity  inositol phosphate metabolic process  phosphatidylinositol phosphorylation  inositol phosphate dephosphorylation  inositol monophosphate 3-phosphatase activity  inositol monophosphate 4-phosphatase activity  inositol monophosphate phosphatase activity  extracellular exosome  
Ontology : EGO-EBImagnesium ion binding  protein binding  cytoplasm  cytosol  inositol metabolic process  inositol biosynthetic process  phosphatidylinositol biosynthetic process  phosphate-containing compound metabolic process  signal transduction  inositol monophosphate 1-phosphatase activity  inositol monophosphate 1-phosphatase activity  inositol monophosphate 1-phosphatase activity  manganese ion binding  lithium ion binding  identical protein binding  protein homodimerization activity  inositol phosphate metabolic process  phosphatidylinositol phosphorylation  inositol phosphate dephosphorylation  inositol monophosphate 3-phosphatase activity  inositol monophosphate 4-phosphatase activity  inositol monophosphate phosphatase activity  extracellular exosome  
Pathways : KEGGInositol phosphate metabolism    Phosphatidylinositol signaling system   
NDEx NetworkIMPA1
Atlas of Cancer Signalling NetworkIMPA1
Wikipedia pathwaysIMPA1
Orthology - Evolution
OrthoDB3612
GeneTree (enSembl)ENSG00000133731
Phylogenetic Trees/Animal Genes : TreeFamIMPA1
HOVERGENP29218
HOGENOMP29218
Homologs : HomoloGeneIMPA1
Homology/Alignments : Family Browser (UCSC)IMPA1
Gene fusions - Rearrangements
Fusion : MitelmanZNF704/IMPA1 [8q21.13/8q21.13]  [t(8;8)(q21;q21)]  
Fusion: TCGAZNF704 8q21.13 IMPA1 8q21.13 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIMPA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IMPA1
dbVarIMPA1
ClinVarIMPA1
1000_GenomesIMPA1 
Exome Variant ServerIMPA1
ExAC (Exome Aggregation Consortium)IMPA1 (select the gene name)
Genetic variants : HAPMAP3612
Genomic Variants (DGV)IMPA1 [DGVbeta]
DECIPHERIMPA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIMPA1 
Mutations
ICGC Data PortalIMPA1 
TCGA Data PortalIMPA1 
Broad Tumor PortalIMPA1
OASIS PortalIMPA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIMPA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIMPA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IMPA1
DgiDB (Drug Gene Interaction Database)IMPA1
DoCM (Curated mutations)IMPA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IMPA1 (select a term)
intoGenIMPA1
Cancer3DIMPA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602064    617323   
Orphanet
MedgenIMPA1
Genetic Testing Registry IMPA1
NextProtP29218 [Medical]
TSGene3612
GENETestsIMPA1
Target ValidationIMPA1
Huge Navigator IMPA1 [HugePedia]
snp3D : Map Gene to Disease3612
BioCentury BCIQIMPA1
ClinGenIMPA1 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3612
Chemical/Pharm GKB GenePA29860
Clinical trialIMPA1
Miscellaneous
canSAR (ICR)IMPA1 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIMPA1
EVEXIMPA1
GoPubMedIMPA1
iHOPIMPA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:04:02 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.