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IMPAD1 (inositol monophosphatase domain containing 1)

Identity

Alias_symbol (synonym)FLJ20421
IMPA3
gPAPP
Other aliasGPAPP
IMP 3
IMP-3
HGNC (Hugo) IMPAD1
LocusID (NCBI) 54928
Atlas_Id 64611
Location 8q12.1  [Link to chromosome band 8q12]
Location_base_pair Starts at 57870488 and ends at 57906430 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
IMPAD1 (8q12.1) / ZCCHC24 (10q22.3)RPS20 (8q12.1) / IMPAD1 (8q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IMPAD1   26019
Cards
Entrez_Gene (NCBI)IMPAD1  54928  inositol monophosphatase domain containing 1
AliasesGPAPP; IMP; IMP-3; IMPA3
GeneCards (Weizmann)IMPAD1
Ensembl hg19 (Hinxton)ENSG00000104331 [Gene_View]  chr8:57870488-57906430 [Contig_View]  IMPAD1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104331 [Gene_View]  chr8:57870488-57906430 [Contig_View]  IMPAD1 [Vega]
ICGC DataPortalENSG00000104331
TCGA cBioPortalIMPAD1
AceView (NCBI)IMPAD1
Genatlas (Paris)IMPAD1
WikiGenes54928
SOURCE (Princeton)IMPAD1
Genetics Home Reference (NIH)IMPAD1
Genomic and cartography
GoldenPath hg19 (UCSC)IMPAD1  -     chr8:57870488-57906430 -  8q12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)IMPAD1  -     8q12.1   [Description]    (hg38-Dec_2013)
EnsemblIMPAD1 - 8q12.1 [CytoView hg19]  IMPAD1 - 8q12.1 [CytoView hg38]
Mapping of homologs : NCBIIMPAD1 [Mapview hg19]  IMPAD1 [Mapview hg38]
OMIM614010   614078   
Gene and transcription
Genbank (Entrez)AI095394 AK000428 AK090988 AY032885 BC017797
RefSeq transcript (Entrez)NM_017813
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_031926 NT_008183 NW_004929339
Consensus coding sequences : CCDS (NCBI)IMPAD1
Cluster EST : UnigeneHs.438689 [ NCBI ]
CGAP (NCI)Hs.438689
Alternative Splicing GalleryENSG00000104331
Gene ExpressionIMPAD1 [ NCBI-GEO ]   IMPAD1 [ EBI - ARRAY_EXPRESS ]   IMPAD1 [ SEEK ]   IMPAD1 [ MEM ]
Gene Expression Viewer (FireBrowse)IMPAD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54928
GTEX Portal (Tissue expression)IMPAD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NX62   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NX62  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NX62
Splice isoforms : SwissVarQ9NX62
Catalytic activity : Enzyme3.1.3.25 [ Enzyme-Expasy ]   3.1.3.253.1.3.25 [ IntEnz-EBI ]   3.1.3.25 [ BRENDA ]   3.1.3.25 [ KEGG ]   
PhosPhoSitePlusQ9NX62
Domaine pattern : Prosite (Expaxy)IMP_2 (PS00630)   
Domains : Interpro (EBI)Inositol_monophosphatase    Inositol_monophosphatase_CS   
Domain families : Pfam (Sanger)Inositol_P (PF00459)   
Domain families : Pfam (NCBI)pfam00459   
Conserved Domain (NCBI)IMPAD1
DMDM Disease mutations54928
Blocks (Seattle)IMPAD1
SuperfamilyQ9NX62
Human Protein AtlasENSG00000104331
Peptide AtlasQ9NX62
HPRD06531
IPIIPI00787853   IPI00166336   IPI00984534   IPI00979114   
Protein Interaction databases
DIP (DOE-UCLA)Q9NX62
IntAct (EBI)Q9NX62
FunCoupENSG00000104331
BioGRIDIMPAD1
STRING (EMBL)IMPAD1
ZODIACIMPAD1
Ontologies - Pathways
QuickGOQ9NX62
Ontology : AmiGOendochondral ossification  chondrocyte development  Golgi apparatus  inositol biosynthetic process  3'-nucleotidase activity  3'(2'),5'-bisphosphate nucleotidase activity  inositol monophosphate 1-phosphatase activity  post-embryonic development  membrane  integral component of membrane  dephosphorylation  chondroitin sulfate metabolic process  embryonic digit morphogenesis  phosphatidylinositol phosphorylation  metal ion binding  inositol monophosphate 3-phosphatase activity  inositol monophosphate 4-phosphatase activity  
Ontology : EGO-EBIendochondral ossification  chondrocyte development  Golgi apparatus  inositol biosynthetic process  3'-nucleotidase activity  3'(2'),5'-bisphosphate nucleotidase activity  inositol monophosphate 1-phosphatase activity  post-embryonic development  membrane  integral component of membrane  dephosphorylation  chondroitin sulfate metabolic process  embryonic digit morphogenesis  phosphatidylinositol phosphorylation  metal ion binding  inositol monophosphate 3-phosphatase activity  inositol monophosphate 4-phosphatase activity  
Pathways : KEGGInositol phosphate metabolism    Sulfur metabolism    Phosphatidylinositol signaling system   
NDEx NetworkIMPAD1
Atlas of Cancer Signalling NetworkIMPAD1
Wikipedia pathwaysIMPAD1
Orthology - Evolution
OrthoDB54928
GeneTree (enSembl)ENSG00000104331
Phylogenetic Trees/Animal Genes : TreeFamIMPAD1
HOVERGENQ9NX62
HOGENOMQ9NX62
Homologs : HomoloGeneIMPAD1
Homology/Alignments : Family Browser (UCSC)IMPAD1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIMPAD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IMPAD1
dbVarIMPAD1
ClinVarIMPAD1
1000_GenomesIMPAD1 
Exome Variant ServerIMPAD1
ExAC (Exome Aggregation Consortium)IMPAD1 (select the gene name)
Genetic variants : HAPMAP54928
Genomic Variants (DGV)IMPAD1 [DGVbeta]
DECIPHER (Syndromes)8:57870488-57906430  ENSG00000104331
CONAN: Copy Number AnalysisIMPAD1 
Mutations
ICGC Data PortalIMPAD1 
TCGA Data PortalIMPAD1 
Broad Tumor PortalIMPAD1
OASIS PortalIMPAD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIMPAD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIMPAD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IMPAD1
DgiDB (Drug Gene Interaction Database)IMPAD1
DoCM (Curated mutations)IMPAD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IMPAD1 (select a term)
intoGenIMPAD1
Cancer3DIMPAD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614010    614078   
Orphanet20478   
MedgenIMPAD1
Genetic Testing Registry IMPAD1
NextProtQ9NX62 [Medical]
TSGene54928
GENETestsIMPAD1
Huge Navigator IMPAD1 [HugePedia]
snp3D : Map Gene to Disease54928
BioCentury BCIQIMPAD1
ClinGenIMPAD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54928
Chemical/Pharm GKB GenePA142671657
Clinical trialIMPAD1
Miscellaneous
canSAR (ICR)IMPAD1 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIMPAD1
EVEXIMPAD1
GoPubMedIMPAD1
iHOPIMPAD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:08:50 CET 2017

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